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Full-Text Articles in Women's Health
Safety And Efficacy Of Bioidentical Hormone Therapy In Menopause: A Literature Review, Kathryn Akre
Safety And Efficacy Of Bioidentical Hormone Therapy In Menopause: A Literature Review, Kathryn Akre
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Vasomotor symptoms (VMS) experienced during menopause can negatively impact a woman’s quality of life, productivity, sleep, and mood. Systemic hormone therapy (HT) is the most effective treatment for moderate to severe VMS, however safety concerns raised by the 2002 Women’s Health Initiative (WHI) trial have led to a decrease in overall HT use and a growing demand for custom-compounded bioidentical HT. Misconceptions regarding the superior safety and efficacy of custom-compounded hormones and lack of clinician expertise in menopause management contribute to ongoing uncertainty and low uptake of United States (U.S.) Food and Drug Administration (FDA) approved bioidentical HT products. This …