Public Health Commons^™

A Comparative Analysis Of Hiv/Aids In France And The United States: Historical Context And Preventative Actions, Rebecca A. Liebsack

Honors Theses

The HIV/AIDS pandemic is the result of transmission of a zoonotic disease known as simian immunodeficiency virus. The pandemic has had profound social and economic consequences and continues to be present today. France and the United States’ response to the discovery of HIV will be compared and the impact that HIV/AIDS had on their countries and future responses. They had rather similar responses, however, the United States had a slower initial response compared to France. Both had similar takeaways such as aiming at improving prevention and utilizing tactics developed during the start of the pandemic like frequent testing and vaccines.

Building Up A Genomic Surveillance Platform For Sars-Cov-2 In The Middle Of A Pandemic: A True North-South Collaboration, Waqasuddin Khan, Furqan Kabir, Samiah Kanwar, Fatima Aziz, Sahrish Muneer, Adil Kalam, Mehdia Ali, Nadia Ansari, Fyezah Jehan, Muhammad Imran Nisar

Department of Paediatrics and Child Health

Next-generation sequencing technology has revolutionised pathogen surveillance over the last two decades. However, the benefits are not equitably distributed, with developing countries lagging far behind in acquiring the required technology and analytical capacity. Recent declines in the cost associated with sequencing-equipment and running consumables have created an opportunity for broader adoption. During the COVID-19 pandemic, rapid diagnostics development and DNA sequencing revolutionised the ability to diagnose and sequence SARS-CoV-2 rapidly. Socioeconomic inequalities substantially impact the ability to sequence SARS-CoV-2 strains and undermine a developing country's pandemic preparedness. Low- and middle-income countries face additional challenges in establishing, maintaining and expanding genomic …

Pandemic Response Officers: Integration Between Medical, Public Health, And Higher Education Systems To Expedite Prevention And Response., Anne C Jones, Genevive R Meredith, Donna Leong, Sabine Jamal, Rachel Buckwalter, John D Clarke, Marin Clarkberg, Allan Bishop, Frank Cantone, Claire Espey, Frank Kruppa, Mary George Opperman, Gary A Koretzky

Rowan-Virtua School of Osteopathic Medicine Faculty Scholarship

CONTEXT: Research and policy studies alike have enumerated population and community health benefits of system integration between medical, public health, and social entities. The emergence of the COVID-19 pandemic revealed the necessity of a well-trained and adequately staffed public health and medical workforce in order to process SARS-CoV-2 cases and prevent subsequent transmission. Higher education systems, in particular, represented defined populations of exposure and transmission. Opportunities existed for collaboration and task sharing between institutions of higher education and local public health departments to limit spread and impacts.

PROGRAM: This article describes the Pandemic Response Officer (PRO) program at Cornell University, …

A Phase 1a/1b Clinical Trial Design To Assess Safety, Acceptability, Pharmacokinetics And Tolerability Of Intranasal Q-Griffithsin For Covid-19 Prophylaxis, Henry W. Nabeta, Maryam Zahin, Joshua L. Fuqua, Elizabeth D. Cash, Ingrid Leth, Michael Strauss, Jeanne Novak, Lin Wang, Angela Siegwald, Rachel A. Sheppard, Shesh N. Rai, Lisa C. Rohan, Sharon Hillier, Gerald W. Dryden, Kevin L. Potts, Kenneth E. Palmer

The University of Louisville Journal of Respiratory Infections

Background: The COVID-19 pandemic remains an ongoing threat to global public health. Q-Griffithsin (Q-GRFT) is a lectin that has demonstrated potent broad-spectrum inhibitory activity in preclinical studies in models of Nipah virus and the beta coronaviruses SARS-CoV, MERS-CoV, and SARS-CoV-2.

Methods: Here, we propose a clinical trial design to test the safety, pharmacokinetics (PK), and tolerability of intranasally administered Q-GRFT for the prevention of SARS-CoV-2 infection as a prophylaxis strategy. The initial Phase 1a study will assess the safety and PK of a single dose of intranasally administered Q-GRFT. If found safe, the safety, PK, and tolerability of multiple doses …

Navigating Post-Covid A Guide For Young Adults Recovering From Mild To Moderate Cases Of Covid-19, Chesley Ferris

Muskie School Capstones and Dissertations

COVID-19 is a new strain of the Human Coronavirus. There are many types of Human Coronavirus, with COVID-19, or the Coronavirus Disease, being discovered in December 2019. COVID-19 is classified as a mild to severe upper respiratory illness. It can affect people differently, with some being asymptomatic, or having no symptoms, and others having mild, to moderate or severe symptoms. Symptoms can also present differently in each person. One person may not have the same symptoms as another.The virus is easily transmittable, meaning it can travel from person to person quickly and easily. This is why it is important to …

Impact Of Covid-19 On Ohio's National Parks Visitation, Ryan Grzeschik

Williams Honors College, Honors Research Projects

The COVID-19 pandemic has fundamentally changed the way in which society operates in order to get the novel disease under control. Businesses throughout the United States have had to close or reduce provided services, stay at home orders have secluded many people, and social distancing limits contact between others so many are turning to the parks system to cope with these changes. This study aims to find how the visitation of national parks in Ohio have been affected through the first six months of the pandemic. Visitation statistics were compared from March to August of 2020 to those same months …

Zika Virus: Infectious Process And Public Health Response, Morgan Homan, Julia Dickman, Jenna Deininger, Austin Hopkins, Olivia Henton, Steven N. Leonard

Pharmacy and Wellness Review

The Zika virus has become a growing concern as a global pandemic. Since being identified in Uganda in 1947, the virus has spread around the world, recently emerging in South America with a great impact on Brazil. As of 2016, Zika has made its appearance in the United States and is now actively being transmitted in Florida. The virus is a mosquito-vectored flavivirus primarily transmitted by the Aedes mosquito which infects a human through biting. Transmission through sexual intercourse is also possible as well as transmission from a pregnant woman to her fetus. This latter form of transmission presents the …

Guinea-Bissau: Hiv/Aids, Matt Macarthur

Global Public Health

This public health brief investigates the concern of HIV/AIDS in Guinea-Bissau. Guinea-Bissau is a low-income country run by a semi-presidential government. The government has been very unstable since its formation. A variety of internal conflicts have limited the effectiveness of the government. As a result, there is little money to provide proper treatment for individuals with HIV/AIDS. It is important to get tested for this condition as soon as symptoms occur, but due to limited resources that is not always possible. Guinea-Bissau has a very high fertility rate compared to other countries worldwide, this allows for a high mother-to-child transmission …

Somalia: Rift Valley Fever, Alyson Meeks

Global Public Health

This walks readers through the basic demographics of Somalia, a country located in the horn of Africa. After learning about the government in Somalia and the problems that the people of the country face, this focuses on the problem of Rift Valley Fever. Rift Valley Fever is a virus that year after year strikes Somalia and surrounding countries. Weather patterns seem to help predict when Rift Valley Fever will be at the highest risk for an outbreak. This outlines the steps the current government and people are trying to take to help prevent outbreaks of RVF. But the solutions currently …

Vanuatu: Malaria, Cody Wheeler

Global Public Health

Vanuatu is a small archipelago near Australia with a population of over 280,000. This nation consists of almost all native Vanuatuans, who live in rural areas. This young nation, only 40 years of independence, has many issues ranging from infantile mortality to an underdeveloped infrastructure, water and sanitation issues. This brief’s focus is the endemic of malaria, specifically the Plasmodium falciparum and P. vivax strains of the disease. The nation is attempting to manage the issue through implementation of screening and better testing for malaria. The use of insecticide treated nets (ITNs) is also prevalent, but in some areas the …

Tanzania: Hiv/Aids, Francis Faasen

Global Public Health

Tanzania has a lot of issues going on in the community, but HIV/AIDS is the number one issue they are facing. Over 5% of their population has the HIV/Aids virus. There are many interventions that have been tried in Tanzania. In the last year there have been over 50,000 new cases of HIV/Aids in Tanzania. The goal is to main those numbers go down dramatically in the coming years. The two most common interventions are trying to educate this subject at a young age and provide condoms to the population. They tried giving condoms out to the people of Tanzania …

Mozambique: Hiv/Aids, Camila Davila

Global Public Health

Mozambique is a country located in Southeastern Africa near the Mozambique Channel and the Indian Ocean. The president of this nation is Filipe Jacinto Nyusi. The total population is 26, 573, 706 which is composed of mostly 99.68% Africans and other minorities. Its national language is Portuguese although most of the population speaks Emarkhuwa. Most of the population is Catholic and a few others include Muslims and Zionist Christians. Mozambique faces several challenges with malaria, poverty, malnutrition, HIV/AIDS, and illicit drugs. HIV/AIDS is a common health problem that targets the immune system and is transmitted through bodily fluids such as …

Trinidad & Tobago : Hiv Epidemic, Madison Caldwell

Global Public Health

Trinidad and Tobago are twin islands located in the Caribbean off the coast of Venezuela. In the recent years since about 1990, citizens of this country have been greatly affected by the HIV epidemic. HIV stands for human immunodeficiency virus and is spread through infected seman, blood, or vaginal fluids usually through sexual intercourse. As this virus continues to progress in the body, it will eventually turn into AIDS, which stands for acquired immunodeficiency syndrome. Once HIV progresses to AIDS, the outcome is ultimately fatal, hence why there is a dire need to promote awareness and methods of intervention to …

Evaluating The Effectivesness Of Information Sources Regarding Hiv Among Gold Miners In Quảng Nam, Noah Landesberg

Independent Study Project (ISP) Collection

Young migrant males in strenuous manual labor environments represent a high-­‐risk population for the transmission of HIV/AIDS. In Vietnam, gold miners are representative of this high-­‐risk population. Phước Sơn district, Quảng Nam province is home to much of Vietnam’s mining activity and has a comparatively high rate of HIV. Previous studies have been done on HIV/AIDS prevalence in Quảng Nam as well as related knowledge and practices. This analysis of a 2014 questionnaire examines the effects of varying information sources on HIV/AIDS knowledge. The sample of workers was mostly male and between 25 and 49 years old. Migrants made up …

Dengue And Aedes Aegypti: A Public Health Problem Along The United States-Mexico Border (Lecture Number 1 - A Series Of Dengue Lectures), Frank Cortez Flores

Frank Cortez Flores

My primary public health interest is the reemerging arboviral infections (e.g., dengue) that are increasing in incidence, expanding into new geographic areas, affecting new populations, and are threatening to increase in the near future, especially following a natural disaster (e.g., hurricanes). The goal of the dengue lecture series is to promote the recognition of dengue and dengue hemorrhagic fever and improve the understanding of factors involved in prevention, surveillance and control of the Aedes aegypti mosquito, the principal mosquito vector of dengue virus. The purpose of these lectures is to accelerate learning and development of an effective dengue prevention and …

Dengue Fever - A Public Health Problem Along The Texas-Mexico Border, Frank Cortez Flores

Frank Cortez Flores

My primary public health interest is the reemerging arboviral infections (e.g., dengue) that are increasing in incidence, expanding into new geographic areas, affecting new populations, and are threatening to increase in the near future, especially following a natural disaster (e.g., hurricanes). The goal of the dengue lecture series is to promote the recognition of dengue and dengue hemorrhagic fever and improve the understanding of factors involved in prevention, surveillance and control of the Aedes aegypti mosquito, the principal mosquito vector of dengue virus. The purpose of these lectures is to accelerate learning and development of an effective dengue prevention and …