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HIV

2014

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Articles 1 - 30 of 33

Full-Text Articles in Public Health

Generational Inversions: 'Working' For Social Reproduction Amid Hiv In Swaziland, Casey Golomski Dec 2014

Generational Inversions: 'Working' For Social Reproduction Amid Hiv In Swaziland, Casey Golomski

Anthropology

How do people envision social reproduction when regular modes of generational succession and continuity are disrupted in the context of HIV/AIDS? How and where can scholars identify local ideas for restoring intergenerational practices of obligation and dependency that produce mutuality rather than conflict across age groups? Expanding from studies of HIV/AIDS and religion in Africa, this article pushes for an analytic engagement with ritual as a space and mode of action to both situate local concerns about and practices for restoring dynamics of social reproduction. It describes how the enduring HIV/AIDS epidemic in Swaziland contoured age patterns of mortality where …


Strengthening Hiv Knowledge And Awareness Among Undergraduate Students At Historically Black Colleges And Universities, Ashley Murray, Monica J. Huang, Felicia Hardnett, Madeline Y. Sutton Nov 2014

Strengthening Hiv Knowledge And Awareness Among Undergraduate Students At Historically Black Colleges And Universities, Ashley Murray, Monica J. Huang, Felicia Hardnett, Madeline Y. Sutton

Journal of Health Disparities Research and Practice

Objective: We describe baseline HIV knowledge among students at historically black colleges and universities (HBCUs) to inform and strengthen HIV education efforts at HBCUs.

Methods: We surveyed 1,230 African American HBCU students from 24 HBCUs; 1,051 responses (85.4 %) were analyzable.

Results: Although general HIV knowledge was high among respondents (95% of students correctly responded that having sex without a condom constituted unsafe sex), knowledge deficits were noted (only 25% of students reported that multiple sex partners is a form of unsafe sex, while 25% of students reported that withdrawal of the penis before ejaculation reduced HIV …


Navigating Life With Hiv: The Lived Experiences Of Youth Living With Hiv, Tamara M M Landry Nov 2014

Navigating Life With Hiv: The Lived Experiences Of Youth Living With Hiv, Tamara M M Landry

Electronic Thesis and Dissertation Repository

Youth and young adults living with HIV, between the ages of 15 and 29 represent one-quarter of the new infection rates in Canada, but little is known about the safer sex practices, HIV disclosure processes and coping mechanisms used by this important but often neglected group to manage the every day realities of living with HIV. The primary objectives of this study were to gather qualitative data about the lived experiences of Canadian youth who are living with HIV and enhance our understanding of their experiences of becoming HIV-positive, navigating issues related to safer sex and HIV disclosure, and managing …


Not On My Street: Exploration Of Culture, Meaning And Perceptions Of Hiv Risk Among Middle Class African American Women, Corliss D. Heath Nov 2014

Not On My Street: Exploration Of Culture, Meaning And Perceptions Of Hiv Risk Among Middle Class African American Women, Corliss D. Heath

USF Tampa Graduate Theses and Dissertations

Black women remain at a higher risk for HIV infection than women of any other ethnic group. Of all new infections reported among U.S. women in 2010, 64% occurred in African Americans compared to 18% Whites and 15% Hispanic/Latina women (CDC 2013a; CDC 2014b). While the literature on HIV risk among African American women is extensive, it mostly focuses on low income, low education subgroups of women or those involved in high risk behaviors such as drug use. Very little has been done to understand the risk for HIV among college educated, middle class women who do not fit into …


The Influence Of Gene Environment Interaction On The Risk Of Cognitive Impairment: Reducing Sexual Risk Behaviors And Alcohol Use In Hiv-Infected Adults, Karina Villalba Phd Nov 2014

The Influence Of Gene Environment Interaction On The Risk Of Cognitive Impairment: Reducing Sexual Risk Behaviors And Alcohol Use In Hiv-Infected Adults, Karina Villalba Phd

FIU Electronic Theses and Dissertations

Memory deficits and executive dysfunction are highly prevalent among HIV-infected adults. These conditions can affect their quality of life, antiretroviral adherence, and HIV risk behaviors. Several factors have been suggested including the role of genetics in relation to HIV disease progression. This dissertation aimed to determine whether genetic differences in HIV-infected individuals were correlated with impaired memory, cognitive flexibility and executive function and whether cognitive decline moderated alcohol use and sexual transmission risk behaviors among HIV-infected alcohol abusers participating in an NIH-funded clinical trial comparing the efficacy of the adapted Holistic Health Recovery Program (HHRP-A) intervention to a Health Promotion …


Psychological Fears Among Low-Paid Female Sex Workers In Southwest China And Their Implications For Hiv Prevention, Shan Qiao Ph.D., Xiaoming Li Ph.D., Chen Zhang, Yuejiao Zhou, Zhiyong Shen, Zhenzhu Tang, Bonita Stanton Oct 2014

Psychological Fears Among Low-Paid Female Sex Workers In Southwest China And Their Implications For Hiv Prevention, Shan Qiao Ph.D., Xiaoming Li Ph.D., Chen Zhang, Yuejiao Zhou, Zhiyong Shen, Zhenzhu Tang, Bonita Stanton

Faculty Publications

Commercial sex plays a critical role in rapidly increasing heterosexual transmission of HIV in China. Low-paid female sex workers (FSWs) are especially vulnerable to HIV/AIDS. Because of the illegality and stigma associated with sex work, FSWs may constantly live with fears in their daily life. Based on cross-sectional study of 794 low-paid FSWs in China we described their psychological fears related to commercial sex and examined the associations between fears and HIV-related behaviors. Fear of HIV infection was significantly associated with consistent use of condoms with clients. However, fear of breaching sex worker identity significantly prevented the FSWs from consistently …


Who Guidance Grounded In A Comprehensive Approach To Sexual And Reproductive Health And Human Rights: Topical Pre-Exposure Prophylaxis, Manjula Lusti-Narasimhan, Rajat Khosla, Rachel Baggaley, Marleen Temmerman, Elizabeth Mcgrory, Tim Farley Sep 2014

Who Guidance Grounded In A Comprehensive Approach To Sexual And Reproductive Health And Human Rights: Topical Pre-Exposure Prophylaxis, Manjula Lusti-Narasimhan, Rajat Khosla, Rachel Baggaley, Marleen Temmerman, Elizabeth Mcgrory, Tim Farley

Obstetrics and Gynaecology, East Africa

Introduction: Two new microbicide products based on topical (vaginal) application of antiretroviral drugs – 1% tenofovir gel and the dapivirine ring – are currently in late-stage clinical testing, and results on their safety and effectiveness are expected to become available in early 2015. WHO guidelines on the use of topical pre-exposure prophylaxis (topical PrEP) are important in order to ensure that these new prevention products are optimally used.

Discussion: Given that these new topical PrEP products are designed to be woman initiated and will likely be delivered in reproductive health settings, it is important to ensure that the …


Women’S Hiv Prevention Study (Whips): A Proposal To Pilot Test An Hiv Intervention For Older African American Women Living With Hiv, Charsey Cherry Aug 2014

Women’S Hiv Prevention Study (Whips): A Proposal To Pilot Test An Hiv Intervention For Older African American Women Living With Hiv, Charsey Cherry

Theses and Dissertations

Despite improvements in treatments over the past 30 years, HIV /AIDS continues to be a major public health threat, particularly among sub-populations such as African American women. Midlife and older adults (those aged 40 years and over) are fast becoming a growing concern for HIV/AIDS infections, particularly older African American women. There has been limited research targeting midlife and older African American women living with HIV that aimed to reduce their transmission of HIV and promote them becoming prevention advocates. In response to this gap in the literature, a culturally tailored intervention guided by the IMB Model of behavior change …


Intimacy Uncertainty And Identity In Gay Male Couples Dealing With A Serodiscordant Hiv Status, Scott Allen Eldredge Aug 2014

Intimacy Uncertainty And Identity In Gay Male Couples Dealing With A Serodiscordant Hiv Status, Scott Allen Eldredge

Doctoral Dissertations

When individuals are diagnosed with a chronic illness, their lives instantly change. Daily routines are interrupted and attendance to the symptoms and side effects of illness and medication becomes a daily chore. However, the patient is not the only one that feels the disruptive effects of illness and the partner of the chronically ill patient must also contend with the daily effects of an illness that they themselves do not have. In the case of HIV, the infectious nature of the disease, along with the stigma associated with the disease, serve to be additional sources of stress in an already-stressful …


“Work What You Got”: Political Participation And Hiv-Positive Black Women’S Work To Restore Themselves And Their Communities, Monica L. Melton Aug 2014

“Work What You Got”: Political Participation And Hiv-Positive Black Women’S Work To Restore Themselves And Their Communities, Monica L. Melton

Journal of Interdisciplinary Feminist Thought

Black women’s rates of HIV/AIDS infection have skyrocketed in comparison to other racial and ethnic groups over the past thirty years. Despite these rates, HIV-positive Black women’s perspectives are rarely sought regarding best practices to eradicate and interrupt HIV/AIDS among African American women, even though historically Black women have often proved phenomenal agents of social change. HIV-positive Black women’s activism has been understudied and input from the community in crisis has rarely been deemed as valuable to public health officials in HIV/AIDS prevention and interventions. Through the narratives of thirty HIV-positive Floridian Black women, I present HIV-positive Black women’s political …


The Impact Of Alcohol On Hiv Prevention And Treatment For South Africans In Primary Healthcare, Michelle Schneider, Matthew Chersich, Marleen Temmerman, Olivier Degomme, Charles D. Parry Aug 2014

The Impact Of Alcohol On Hiv Prevention And Treatment For South Africans In Primary Healthcare, Michelle Schneider, Matthew Chersich, Marleen Temmerman, Olivier Degomme, Charles D. Parry

Obstetrics and Gynaecology, East Africa

Background: Antiretroviral treatment (ART) has substantially reduced morbidity and mortality for HIV patients. In South Africa, with the largest ART programme globally, attention is needed not only on the further expansion of ART coverage, but also on factors which undermine its effectiveness, such as alcohol use.

Objective: Given the decentralised approach of nurse-initiated and -sustained ART in the South African primary health sector, it is important to document key aspects of alcohol use to be conveyed to HIV-positive individuals and those at risk for HIV.

Method: This study comprised a narrative review of relevant literature.

Results: Alcohol acts through both …


Hiv-Positive Parents, Hiv-Positive Children, And Hiv-Negative Children’S Perspectives On Disclosure Of A Parent’S And Child’S Illness In Kenya, Grace Gachanja, Gary J. Burkholder Jr, Aimee Ferraro Jul 2014

Hiv-Positive Parents, Hiv-Positive Children, And Hiv-Negative Children’S Perspectives On Disclosure Of A Parent’S And Child’S Illness In Kenya, Grace Gachanja, Gary J. Burkholder Jr, Aimee Ferraro

Walden Faculty and Staff Publications

HIV disclosure from parent to child is complex and challenging to HIV-positive parents and healthcare professionals. The purpose of the study was to understand the lived experiences of HIV-positive parents and their children during the disclosure process in Kenya. Sixteen HIV-positive parents, seven HIV-positive children, and five HIV-negative children completed semistructured, in-depth interviews. Data were analyzed using the Van Kaam method; NVivo 8 software was used to assist data analysis. We present data on the process of disclosure based on how participants recommended full disclosure be approached to HIV-positive and negative children. Participants recommended disclosure as a process starting at …


Social Actors Fight The Rising Tide Of Hiv In U.S. Southern Poor, Courtenay Sprague, Sara E. Simon Jul 2014

Social Actors Fight The Rising Tide Of Hiv In U.S. Southern Poor, Courtenay Sprague, Sara E. Simon

Center for Peace, Democracy and Development Publications

The greatest number of persons living with HIV in the United States are now living in the South, and they face poorer health outcomes and increased AIDS-related deaths as compared to the rest of the country. The southern United States has a disproportionate share of low-income individuals, with many lacking access to health care and health insurance. Health facilities are also comparatively fewer and more difficult to reach than in other areas of the United States. The impacts of this already poor health infrastructure on low-income people living with HIV in the South can be life-threatening.

This policy brief summarizes …


The Revolving Door Pattern Of Jail Incarceration And Homelessness And Its Influence On Mortality And Morbidity Among New York City Adults, Sungwoo Lim Jun 2014

The Revolving Door Pattern Of Jail Incarceration And Homelessness And Its Influence On Mortality And Morbidity Among New York City Adults, Sungwoo Lim

Dissertations, Theses, and Capstone Projects

Objectives

The purpose of this dissertation study was to identify timing and sequencing of jail incarceration and homelessness by utilizing sequence analysis and to test whether a particular trajectory contributes to mortality risk and discontinuity of HIV care.

Methods

The main data source was an existing matched dataset, constructed using administrative data from the New York City (NYC) Departments of Health and Mental Hygiene, Correction, and Homeless Services. The study cohort consisted of 15,620 NYC adults with recent histories of both jail incarceration and homelessness. Monthly experiences of jail incarceration, homelessness, and community-dwelling in 2001-03 were summarized into trajectory groups …


Hiv Vaccine Acceptability Among High-Risk Drug Users In Appalachia: A Cross-Sectional Study, April M. Young, Ralph J. Diclemente, Daniel S. Halgin, Claire E. Sterk, Jennifer R. Havens May 2014

Hiv Vaccine Acceptability Among High-Risk Drug Users In Appalachia: A Cross-Sectional Study, April M. Young, Ralph J. Diclemente, Daniel S. Halgin, Claire E. Sterk, Jennifer R. Havens

Epidemiology and Environmental Health Faculty Publications

BACKGROUND: A vaccine could substantially impact the HIV epidemic, but inadequate uptake is a serious concern. Unfortunately, people who use drugs, particularly those residing in rural communities, have been underrepresented in previous research on HIV vaccine acceptability. This study examined HIV vaccine acceptability among high-risk drug users in a rural community in the United States.

METHODS: Interviewer-administered questionnaires included questions about risk behavior and attitudes toward HIV vaccination from 433 HIV-negative drug users (76% with history of injection) enrolled in a cohort study in Central Appalachia. HIV vaccine acceptability was measured on a 4-point Likert scale. Generalized linear mixed models …


Hiv And Sti Risk For Young Blacks In High Prevalence Areas: Implications For Health Equity In Communities Hosting Historically Black Colleges And Universities (Hbcus), Tanya Telfair Leblanc, Madeline Y. Sutton, Peter Thomas, Wayne A. Duffus May 2014

Hiv And Sti Risk For Young Blacks In High Prevalence Areas: Implications For Health Equity In Communities Hosting Historically Black Colleges And Universities (Hbcus), Tanya Telfair Leblanc, Madeline Y. Sutton, Peter Thomas, Wayne A. Duffus

Journal of Health Disparities Research and Practice

Background

Every year, thousands of young, black, high school graduates who are seeking higher education, attend one of the 105 historically black colleges and universities (HBCUs) located primarily in the south and east. The objective of the research was to examine the geographic proximity of HBCUs to areas of high HIV and STI disease burden among college age people to assess infectivity of potential sex partners in the areas surrounding HBCUs.

Methods

We examined the 14 states reporting the greatest HIV diagnoses burden among persons age 20-24 years old and STI burden among persons age 15 to 24 years old …


Social Determinants Of Late Presentation To Hiv Care, Connie Leeper, Michael Mugavero, James Willig, Eric Chamot, Shatomi Kerbawy, Anne Zinski May 2014

Social Determinants Of Late Presentation To Hiv Care, Connie Leeper, Michael Mugavero, James Willig, Eric Chamot, Shatomi Kerbawy, Anne Zinski

Journal of Health Disparities Research and Practice

Background: In recent years, increased attention has shifted toward evaluating social determinants of health, and understanding how community, environment, and system factors affect health outcomes. HIV policies and guidelines emphasize the importance of earlier HIV diagnosis and presentation for care. This study evaluated the role of individual and community-level factors in late presentation to HIV care.

Methods: HIV-infected patients newly initiating outpatient HIV medical care at an academic medical center between 2005-2010 were included. Patients' self-reported addresses at their first clinic visit were geocoded using geographic information systems software to the appropriate United States census block group. Using …


To Test Or Not To Test: Barriers And Solutions To Testing African American College Students For Hiv At A Historically Black College/University, Naomi M. Hall-Byers, Jennifer Peterson, Malynnda Johnson May 2014

To Test Or Not To Test: Barriers And Solutions To Testing African American College Students For Hiv At A Historically Black College/University, Naomi M. Hall-Byers, Jennifer Peterson, Malynnda Johnson

Journal of Health Disparities Research and Practice

Young African Americans are disproportionately affected by sexually transmitted infections, including HIV. The purpose was to identify reasons that African American college students at a historically Black college/university (HBCU) identified as barriers to HIV testing, and how these barriers can be removed. Fifty-seven heterosexual-identified undergraduate students (ages 18-25) attending an HBCU in the southeastern US participated in the study. Latent content analytic techniques were used to code the transcripts for themes and categories, and representative quotations were used in the findings. Qualitative data indicates three main themes used to avoid testing and three themes to encourage testing. Students were forthcoming …


Understanding Hiv Care Delays In The Us South And The Role Of The Social-Level In Hiv Care Engagement/Retention: A Qualitative Study, Courtenay Sprague, Sara E. Simon Apr 2014

Understanding Hiv Care Delays In The Us South And The Role Of The Social-Level In Hiv Care Engagement/Retention: A Qualitative Study, Courtenay Sprague, Sara E. Simon

Center for Peace, Democracy and Development Publications

Introduction: In a significant geographical shift in the distribution of HIV infection, the US South - comprising 17 states - now has the greatest number of adults and adolescents with HIV (PLHIV) in the nation. More than 60% of PLHIV are not in HIV care in Alabama and Mississippi, contrasted with a national figure of 25%. Poorer HIV outcomes raise concerns about HIV-related inequities for southern PLHIV, which warrant further study. This qualitative study sought to understand experiences of low-income PLHIV on the AIDS Drug Assistance Program in engagement and retention in continuous HIV care in two sites in Alabama. …


Development Of A Community-Managed Hiv Case Management Program In Zomba Malawi, Sharon K. Christman Feb 2014

Development Of A Community-Managed Hiv Case Management Program In Zomba Malawi, Sharon K. Christman

Nursing Faculty Presentations

No abstract provided.


Health Policy & Management News, Georgia Southern University Jan 2014

Health Policy & Management News, Georgia Southern University

Health Policy & Management Department News (2011-2018)

  • Rates of Chlamydia, Gonorrhea, and Genital Herpes
  • QI to Improve HIV Reporting


The Sustainable Action Against Hiv And Aids In Communities (Sahacom): Impacts On Health And Quality Of Life Of People Living With Hiv In Cambodia, Siyan Yi, Pheak Chhoun, Samantha Brant, Kelley Kita, Samedy Suong, Kouland Thin, Sovannary Tuot Jan 2014

The Sustainable Action Against Hiv And Aids In Communities (Sahacom): Impacts On Health And Quality Of Life Of People Living With Hiv In Cambodia, Siyan Yi, Pheak Chhoun, Samantha Brant, Kelley Kita, Samedy Suong, Kouland Thin, Sovannary Tuot


This study evaluated the impacts of the Sustainable Action against HIV and AIDS in Communities (SAHACOM) Project on health and quality of life of people living with HIV (PLHIV). Outcome indicators from baseline documentation (2010) were compared to those obtained at midterm (2012) and end line (2014). Results showed that HIV prevalence among pregnant women aged 15–24 attending antenatal care decreased from 0.5% at baseline to 0.3% at midterm and end line. Proportion of PLHIV who were on antiretroviral therapy (ART) 12 months after the initiation of the treatment increased from 85% at baseline and midterm to 89.5% at end …


Tapestry Of Hope: Inspiration & Victory In The Face Of Adversity, Anna Bossert, Amy Surti Jan 2014

Tapestry Of Hope: Inspiration & Victory In The Face Of Adversity, Anna Bossert, Amy Surti

Bridging the Gaps Posters 2014

No abstract provided.


Bartram Healthy Lifestyles Initiative, James Barrett, James Seternus Jan 2014

Bartram Healthy Lifestyles Initiative, James Barrett, James Seternus

Bridging the Gaps Posters 2014

No abstract provided.


Social Determinants Affecting The Mental Health Of Hiv Infected Latino Men Who Have Sex With Men Living On The U.S. - Mexican Border, Oscar Beltran Jan 2014

Social Determinants Affecting The Mental Health Of Hiv Infected Latino Men Who Have Sex With Men Living On The U.S. - Mexican Border, Oscar Beltran

Open Access Theses & Dissertations

The HIV/AIDS global pandemic is more than three decades old, and although the continual advancement of antiretroviral therapies have successfully decreased the mortality rates of people living with HIV/AIDS (PLWHA), little has been done to improve their mental health status and positive inclusion in society (eliminating discrimination and stigma). This is especially true with the Latino PLWHA living in the U.S.-Mexico border area.

This paper presents data from a qualitative study focused on exploring the mental health issues of a subsample of 40 Latino men who have sex with men (MSM) living with HIV/AIDS on the U.S.-Mexico Border. This subsample …


Neighborhood Factors That Contribute To Alcohol Use And Loneliness In Hiv Positive Patients, Erica Kiernan, Eugene Dunne, Barbara Curbow, William Latimer Jan 2014

Neighborhood Factors That Contribute To Alcohol Use And Loneliness In Hiv Positive Patients, Erica Kiernan, Eugene Dunne, Barbara Curbow, William Latimer

Public Health Collection

Background: Neighborhood factors contribute to substance abuse and increased health risk behavior. Alcohol use has adverse consequences as it may interfere with antiretroviral medication adherence. In addition, studies have shown that those who are HIV positive have decreased social network size, limited social support, and social isolation as well as decreased treatment adherence. It is hypothesized that participants with high neighborhood density of alcohol outlets combined with increased feelings of loneliness will be more likely to drink.

Methods: Participants included 85 patients from an HIV treatment clinic in Jacksonville. Interviewer-administered measures included the Alcohol Use Disorders Identification Test …


Patient And System Level Factors As Predictors Of Adherence To Antiretroviral Therapy Appointment Schedules In Cambodia, Gary T. Daigle Jan 2014

Patient And System Level Factors As Predictors Of Adherence To Antiretroviral Therapy Appointment Schedules In Cambodia, Gary T. Daigle

All ETDs from UAB

PATIENT AND SYSTEM LEVEL FACTORS AS PREDICTORS OF ADHERENCE TO ANTIRETROVIRAL THERAPY APPOINTMENT SCHEDULES IN CAMBODIA GARY T. DAIGLE EPIDEMIOLOGY / INTERNATIONAL HEALTH ABSTRACT On-time attendance at clinical appointments by patients on antiretroviral therapy (ART) is essential to the prevention of medication interruptions, viral rebound, drug resistance, and long term mortality. An observational study conducted in 2010, Enablers and Adherence to Antiretroviral Therapy in Cambodia, sought to identify factors that predict on-time clinical appointment attendance by patients on ART. These factors were classified as either ART patient level factors (e.g. demographic, clinical) or patient care and support system level factors …


“I’M Just Like Everyone Else, I Just Happen To Be Hiv Positive”: Challenges Faced By Young Urban Black Women As They Strive To Achieve Normative Life Goals, M N. Mabachi, J K. Dariotis, J Anderson, S Finocchario-Kessler Jan 2014

“I’M Just Like Everyone Else, I Just Happen To Be Hiv Positive”: Challenges Faced By Young Urban Black Women As They Strive To Achieve Normative Life Goals, M N. Mabachi, J K. Dariotis, J Anderson, S Finocchario-Kessler

Manuscripts, Articles, Book Chapters and Other Papers

Younger, low-income, black women are disproportionately affected by the HIV/AIDS epidemic in the U.S. Using thematic analysis of 20 semi-structured interviews with young women receiving HIV care in an urban east coast setting, this study provides insights on how living with HIV influences these women’s future aspirations including economic independence, intimate relationships, and family formation in the context of their socio-cultural and economic environment. One major emergent theme expressed by participants was the desire to be considered normal while seeking to meet the developmental benchmarks of emerging adulthood. Gaining economic independence through education and career opportunities was important, as was …


Growing Up With Hiv In Kisumu, Kenya: Participatory Action Research With Young People Living With Hiv, Zoe Alexis Hobbs Marinkovich Jan 2014

Growing Up With Hiv In Kisumu, Kenya: Participatory Action Research With Young People Living With Hiv, Zoe Alexis Hobbs Marinkovich

Doctoral Dissertations

Forty-one percent of new HIV infections are in young people between the ages of 15-24 (Masquillier, et al., 2012). In addition to new infections, advances in medications are now making it possible for children born with HIV to survive into adolescence and adulthood (Bland, 2011; Gray, 2010). Due to the growing population of youth living with HIV, there is an increased need for adolescent-appropriate care and intervention. While many studies have examined the role of education in preventing HIV transmission for HIV-negative youth in the Sub-Saharan context, few have focused on the education and experiences of young people living with …


Medication Use And Patients Co-Infected With Human Immunodeficiency Virus And Hepatitis C Virus : Quantifying The Prevalence And Identifying The Predictors Of Clinically Significant Drug-Drug Interactions Associated With Therapy Containing First Generation Non-Structural 3a Serine Protease Inhibitors, Nimish Patel Jan 2014

Medication Use And Patients Co-Infected With Human Immunodeficiency Virus And Hepatitis C Virus : Quantifying The Prevalence And Identifying The Predictors Of Clinically Significant Drug-Drug Interactions Associated With Therapy Containing First Generation Non-Structural 3a Serine Protease Inhibitors, Nimish Patel

Legacy Theses & Dissertations (2009 - 2024)

This dissertation enhances our understanding of clinically significant drug-drug interactions (CSDDIs) and contraindicated drug interactions among patients with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) coinfection before and after the addition of HCV therapy including first generation non-structural (NS) 3A serine protease inhibitors. This is important to understand because the clinical sequelae of untreated chronic HCV infection are devastating yet drug-drug interactions greatly complicate treatment for these patients. The HIV/HCV coinfected population is a population that is particularly vulnerable because they are using a high volume of medications. Specifically, the standard of care for patients with HIV infection …