Public Health Commons^™

Dna Methylation And Its Association With Prenatal Exposures And Pregnancy Outcomes, Jennifer Straughen

USF Tampa Graduate Theses and Dissertations

Altered DNA methylation may lead to suboptimal fetal programming, increasing the risk of adverse pregnancy outcomes such as small for gestational age (SGA); however, few studies have examined the associations between DNA methylation, prenatal exposures, and fetal outcomes. Cross-sectional data from a larger, ongoing study were used to assess the impact of prenatal smoking on gene specific methylation of umbilical cord blood derived DNA and to investigate the association between gene-specific methylation and risk of SGA. The association between gene-specific DNA methylation and birthweight was also assessed. Maternal and infant covariates were abstracted from medical records, cigarette smoke exposure was …

Evaluation Of Common Inherited Variants In Mitochondrial-Related And Microrna-Related Genes As Novel Risk Factors For Ovarian Cancer, Jennifer Permuth Wey

USF Tampa Graduate Theses and Dissertations

Epithelial ovarian cancer (EOC) is a leading cause of morbidity and mortality among women in the United States, and the etiology is incompletely understood. Common, low penetrant genetic variants such as single nucleotide polymorphisms (SNPs) likely contribute to a significant proportion of EOC. We examined whether SNPs in two understudied yet biologically important types of genes, mitochondrial-related and miRNA-related genes, may contribute to EOC susceptibility using data from a large, homogeneous study population of 1,815 EOC cases and 1,900 controls (frequency-matched on age-group and race/ethnicity) genotyped through stage 1 of an ongoing genome-wide association study. Inter-individual variation in genes involved …

Epidemiological Study Of Contributing Factors In The Development Of Peptic Ulcer And Gastric Cancer Initiated By Helicobacter Pylori Infection In India, Rahul Suresh Mhaskar

USF Tampa Graduate Theses and Dissertations

Background: Helicobacter pylori (H. pylori) infection is a significant risk factor for peptic ulcer (PU) and gastric cancer (GC). Apart from the virulent CagA genotype of H. pylori environmental and dietary factors influence disease outcomes. There have been no studies addressing these factors in Western India. Hence, we conducted a case control study enrolling PU, GC patients and controls at Pune, India.

Methods: Risk factors for PU and H. pylori infection were assessed in participant interview. H. pylori status was assessed from stool by monoclonal antigen detection. To understand treatment effect, we followed 100 H. pylori positive patients.

Results: We …

The Influence Of Neurocognitive Impairment On Treatment Outcomes Among Drug-Involved People Living With Hiv/Aids, Ifeoma O. Ezeabogu

Master's Theses

Drug- and sex-related HIV risk behaviors and sub-optimal adherence to HIV medication regimens can jeopardize the health of HIV–infected injection drug users (IDUs) and threaten community health. Findings to date indicate that it is feasible to deliver a brief behavioral risk reduction/medication adherence group intervention to HIV-infected IDUs in a community-based setting. Being adherent to HAART or being able to successfully participate in behavioral interventions targeting adherence and harm reduction often requires a relatively high level of cognitive abilities. HIV infection and substance abuse are known to independently affect the central nervous system and this can result in neuro-cognitive impairment. …

Mathematical Modeling, Simulation, And Time Series Analysis Of Seasonal Epidemics., Eric Shu Numfor

Electronic Theses and Dissertations

Seasonal and non-seasonal Susceptible-Exposed-Infective-Recovered-Susceptible (SEIRS) models are formulated and analyzed. It is proved that the disease-free steady state of the non-seasonal model is locally asymptotically stable if R_v < 1, and disease invades if R_v > 1. For the seasonal SEIRS model, it is shown that the disease-free periodic solution is locally asymptotically stable when R̅_v < 1, and I(t) is persistent with sustained oscillations when R̅_v > 1. Numerical simulations indicate that the orbit representing I(t) decays when R̅_v < 1 < R_v. The seasonal SEIRS model with routine and pulse vaccination is simulated, and results depict an unsustained decrease …

Perceptions Of Maternal Stress And Neonatal Patient Outcomes In A Single Private Room Versus Open Room Neonatal Intensive Care Unit Environment., Lisa M. Smithgall

Electronic Theses and Dissertations

Limited clinical evidence exists regarding whether the single private room Neonatal Intensive Care Unit (NICU) environment of care delivery has a positive, negative, or neutral impact on health outcomes for the high risk neonate and on maternal stress as compared to the open room design. The study purpose was to examine whether a difference exists in health outcomes in the open room versus single private room NICU environment. The factors considered were weight gain, ventilator days, hospital length of stay, incidence and grade of intraventricular hemorrhage (IVH), the number of parental visits, and perceptions of maternal stress. Infants hospitalized in …

Cigar Crisis: The Need For Community Based Practices, Christopher D. Watson

Public Health Theses

Considerable evidence exists that little cigars and cigarillos are popular among young adults and that the prevalence is higher among African American young adults.1,2,4 Two brands of little cigars appear most appealing to young smokers - Swisher Sweets and Black and Mild.2,3 This cigar product have been designed by the tobacco industry to appeal specifically for African Americans. In a survey of tobacco use among freshman at a historically black university, there were high rates of little cigar use.4 Little cigar sales have also benefited from the high visibility offered by many celebrities quoted and photographed with cigars, and the …

Effectiveness Of A Pre-Release Planning Program For Hiv-Positive Offenders Exiting Georgia Prisons: A Qualitative Evaluation Approach, Claire A. Willeford

Public Health Theses

Background: Two-year nationwide prison recidivism rates stand at over 60%, and minorities and the poor are at greatest risk both of first-time incarceration and of offending repeatedly over time. Initiatives that may address prison inmates’ lack of resources and increase their success in their communities after release are now an important topic in the study of criminal justice policy. Over the course of the past two decades, the public health concern of HIV/AIDS has increasingly become a part of this discourse on re-entry, as the disease disproportionately affects minority communities both in and outside of prisons. Affected reentrants face not …

A Geographical Examination Of Social, Behavioral, And Demographic Determinants Association With Hepatitis C Viral Infection In The State Of Georgia, Terran A. Terrell

Public Health Theses

Background: Approximately 170 million persons are infected with the hepatitis C viral infection (HCV), globally. Of this number, 3.2 – 4 million persons in the U. S. are infected with HCV. Although previous research has indicated a decrease in the rates of Hepatitis C in the U.S. approximately 12,000 deaths occur annually from those who suffer from chronic liver disease, as a result of being chronic carriers of HCV. Being a recipient of blood transfusions prior to 1992, intravenous drug users (IDUs), or persons with multiple sex partners are associated with increased risk for HCV infection. IDUs constitute the largest …

Elevated Bmi-Associated Characteristics Of Patients With Invasive Mrsa Infection In The Atlanta, Georgia Metro Area, 2005-2008, Lauren R. Lorentzson

Public Health Theses

INTRODUCTION: National obesity rates are leading to higher rates of Type 2 Diabetes, increasing the number of people at risk of invasive infections with Methicillin Resistant Staphylococcus aureus (iMRSA) upon onset of ESRD and hemodialysis. However, an association between adiposity and risk of iMRSA has not been researched. AIM: The purpose of this study is to describe the epidemiological characteristics of an iMRSA cohort in the Atlanta metro area between 2005-2008; to examine BMI-related health outcomes within the cohort; and to compare proportions of BMI categories in this cohort to BRFSS data. METHODS: Surveillance data collected by the CDC EIP …

A Systematic Review Examining The Added Value Of Water, Sanitation, And Hygiene Interventions For Preventive Chemotherapy Programs On Reducing The Prevalence Of Trachoma, Anyess R. Travers

Public Health Theses

BACKGROUND: Trachoma is a leading cause of avoidable blindness. Currently, trachoma is endemic in 57 countries, infects approximately 84 million people globally, and continues to threaten over 10 % of the world’s population with the risk of blindness. Caused by the bacteria Chlamydia trachomatis, blindness due to trachoma is caused by repeated eye infection resulting in the inflammation of the upper eyelid eventually leading the upper lid to pull inward scratching and tearing the cornea causing it to become opaque resulting in loss of vision. The World Health Organization recommends eliminating trachoma as a public health problem using the SAFE …

A Proposal For Enhancing And Measuring Infant-Directed Maternal Utterances And Incidental Teaching Within The Safecare® Parent-Infant Interaction Module, Megan O. Smith

Public Health Theses

Child maltreatment is a serious and pervasive public health problem in the United States. In 2008, there were 772,000 children who were substantiated victims of maltreatment and 1,740 children died as a result of maltreatment. Approximately 33 percent of maltreatment victims were under the age of four. Among numerous other negative sequelae, children who have been maltreated have an elevated incidence of language delay and poor cognitive functioning, both strong predictors of literacy skills and later academic achievement. Further, maternal language input is critical to a child’s cognitive development and language acquisition. Maltreating mothers provide their children with far less …

A Spatial And Health Burden Analysis Of Census Tract 85: Implications For Prevention And Intervention, Allison C. Edwards

Public Health Theses

New regulations requiring not-for-profit hospitals to provide documented evidence of charitable care and community benefits provide a unique opportunity for strategic and targeted investment within the given community of the hospital. And with a growing number of uninsured and underserved in the US, the need for tactical community benefits is increasing exponentially. The purpose of this capstone is to pool together the relevant resources and data necessary to guide and inform the decision making process involved in creating prevention and intervention programs tailored specifically to census tract 85. Utilizing several different forms of demographic and health data including Census, Online …

Mammography Screening Practices And Health Beliefs Of Women In East Tennessee, Peggy A. Johnson

Doctoral Dissertations

Abstract One of every eight women in the United States will be diagnosed with breast cancer in her lifetime. Although early detection of breast cancer is the most effective method of assuring survival, many women throughout the country do not avail themselves of this advantage. This study examined mammography screening practices of women age 55 and older who attended senior citizen centers in rural, non-metro, and metro counties in the areas designated by the Tennessee Department of Health as the Eastern Grand Division of Tennessee. Data was collected from four hundred women from fourteen counties in East Tennessee using the …

The Parents' Role In Childhood Obesity, Heather M. Wintrup

Psychology and Child Development

This paper is an examination of the current childhood obesity crisis in the U.S. and how this epidemic is related to psychological issues. Specifically, the role of parental forces on children’s health attitudes and habits is addressed. The following chapters will define and explain the current situation of childhood obesity, investigate the role parents have in contributing to their children’s weight development, and cover methods of intervention for families dealing with this serious health issue.

The Development And Psychometric Testing Of A Hypertension Knowledge Instrument In A Vulnerable Population, Crescent Elayne Rowell

Theses and Dissertations (ETD)

The primary objective of the study was to assess the psychometric properties of a hypertension knowledge instrument in a vulnerable population. The secondary objective was to determine the association between hypertension knowledge and outcomes such as systolic and diastolic blood pressure and hemoglobin A1c.

A cross-sectional study was conducted using a convenience sample of 196 adults aged 18 years and older with hypertension. Item analysis was conducted to determine the reliability of the instrument. The factor structure was determined and confirmed using exploratory factor analysis and confirmatory factor analysis, respectively. Logistic regression analysis was used to determine the association between …

Effects Of Acculturation On Hiv/Aids Sexual Risk Behaviors Among Asian And Pacific Islander (Api) Women, Margaret Cabotage Salud

Loma Linda University Electronic Theses, Dissertations & Projects

Background. In the US women are the fastest growing group for sexually transmitted infections (STIs), including HIV and AIDS. In addition, the estimated AIDS cases among female adults and adolescents, aged 13-19, increased from 7% in 1985 to approximately 26% in 2002. Most infections occur by heterosexual transmission with 53% occurring through contact with a high-risk sexual partner. While overall HIV/AIDS rates in the Asian Pacific Islander (API) community remain low, they are rising and HIV testing rates, one of the major prevention strategies for HIV, are lower than that of other populations. Furthermore, very little is known about APIs …

Coronary Heart Disease Mortality And Long-Term Exposure To Ambient Particulate Air Pollutants In Elderly Nonsmoking California Residents, Lie Hong Chen

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study is to assess the effect of long-term concentrations of ambient PM on risks of all causes, cardiopulmonary, coronary heart disease (CHD), total cancer, and any mention of nonmalignant respiratory disease (NMRD) mortality.

The health effects of long-term ambient air pollution have been studied with up to 30 years of follow-up in the AHSMOG cohort, a cohort of 6,338 nonsmoking white California adults. Monthly concentrations of ambient air pollutants [particulate matter(PMio), Ozone (O3), sulfur dioxide (SO2), nitrogen dioxide (NO2) or particulate matter

In the AHSMOG cohort, each increment of 10 |ig/m3 in PMio in two-pollutant models …

Parental Attitudes And Perceptions Related To Their Children's Physical Activity And Eating Patterns, Megan Leatham Dubois

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Children's physical inactivity and poor eating patterns have received a great deal of attention in our country and worldwide. Studies have been conducted to identify determinates related to children's physical activity and eating patterns and to identify strategies for promoting positive behaviors. Parental support is a well-accepted determinate of children's physical activity and eating patterns. However, little qualitative research has been done to determine parental attitudes and perceptions related to this critical role.

First, the study sought to gain a greater understanding of parental perspectives on their children's physical activity and eating patterns. Second, the study examined parental attitudes and …

The Role Of Ambient Air Pollution In The Occurrence Of Emphysema, Shiva Metghalchi

Loma Linda University Electronic Theses, Dissertations & Projects

Emphysema is the most common cause of death from respiratory disease in the United States. Emphysema is most common among people aged 50 and older. Those with a genetic predisposition to emphysema may experience the onset as early as their thirties or forties. Men are more likely than women to develop emphysema, but female cases are increasing as the number of female smokers rises.

In the past few years, etiological and pathogenic research has been carried out in an attempt to determine the reason for an increase in deaths and other health problems associated with air pollution, and there have …

Vertical Transmission Of West Nile Virus In Culex Spp. Mosquitoes Of Clark County, Nevada, Vivek K. Raman

UNLV Theses, Dissertations, Professional Papers, and Capstones

West Nile Virus (WNV) is an RNA arbovirus that cycles between mosquitoes and birds, but also infects and causes disease in humans, horses and other vertebrate species. Although most infections are asymptomatic, WNV has emerged as the most common cause of epidemic meningoencephalitis in North America and the leading cause of arboviral encephalitis in the United States.

Mosquitoes of the genus Culex are the most active vectors of WNV in North America. Approximately 85% of human WNV infections in the United States occur in late summer with a peak number of cases in August and September. Vertical transmission is defined …

Effects Of Environmental Prompts On Stair Usage, Lori Andersen

UNLV Theses, Dissertations, Professional Papers, and Capstones

The objective of this study was to evaluate whether environmental prompts placed in two-story buildings on a university campus would increase stair usage. Three buildings were used. One served as a control, while the other two received an intervention. Participants of three buildings were observed taking the stairs and elevator for seven weeks. Baseline data was collected; signs were introduced, and then removed during this time period. Approximately 2700 observations were collected. Environmental prompts did not appear to increase stair usage. There were significant differences in the amount of stair users between buildings. The stair usage rates of this particular …

Youth Can! Grow Healthy!, Andrew Nils Carberry

Masters Theses

This study presents a formative evaluation of an afterschool program that combined youth development and school garden curricula. This program used a novel approach to teach elementary school children about fruits and vegetables and to engage them in advocacy for the physical activity and nutrition environments in their community. The youth development curriculum included sessions on team building, community pride, healthy eating and physical activity, and advocacy. Photovoice was used as a method to allow participants to assess their community and communicate findings with leaders. Participants selected community leaders to invite to their school and shared their findings via a …

The Determinants Of Colorectal Cancer Survival Disparities In Nevada, Lucas N. Wassira

UNLV Theses, Dissertations, Professional Papers, and Capstones

Different population groups across Nevada and throughout the United States suffer disproportionately from colorectal cancer and its after-effects. Overcoming cancer health disparities is important for lessening the burden of cancer. There has been an overall decline in the incidence of and mortality from colorectal cancer (CRC). This is likely due, in part, to the increasing use of screening procedures such as Fecal Occult Blood Test (FOBT) and/or endoscopy, which can reduce the risk of CRC mortality by fifty percent. Nevertheless, screening procedures are routinely used by only fifty percent of Americans aged fifty years and older. Despite overall mortality decreasing …

An Examination Of Known Tuberculosis Risk Factors And Their Correlation Across The United States, David Young

Public Health Theses

Background: Globally tuberculosis (TB) is one of the leading causes of mortality. There is scientific evidence of sociodemographic, behavioral and health risk factors associated with TB infection and TB disease. In the United States (US), there is a low endemicity of TB and a goal of TB elimination. Objective: The primary objective of the study was to examine the correlation of TB risk factors at the state level in the US to obtain insights specific to the state of TB in the US. The risk factors examined were diabetes rates, smoking rates, alcohol abuse rates, AIDS rates, foreign-born vs. US-born, …

Characteristics And Etiology Of Moderate-To-Severe Diarrhea Of Acute, Prolonged Acute, And Persistent Duration Among Children Less Than 5 Years Old In Rural Western Kenya, 2008-2010, Katharine A. Schilling

Public Health Theses

Worldwide, diarrheal disease is the second leading cause of death in children under 5 years old. Data on diarrhea of extended duration is limited. We described the characteristics associated with acute, prolonged acute and persistent diarrhea in Kenyan children less than 5 years of age participating in the Global Enterics Multicenter Study. Children presenting at a clinic were enrolled if they met the case definition for acute moderate-to-severe diarrhea defined as >3 loose stools in the last 24 hrs, within 7 days of illness onset, with >1 of the following: sunken eyes, skin tenting, dysentery, IV rehydration, or hospitalization. To …

The Health Of Ontario’S Transgender Communities: Prevalence Of And Risk Factors For Depression, "Do-It-Yourself" Transitions, And Health Effects Of Cross-Sex Hormones And Surgeries, Nooshin Khobzi

Electronic Thesis and Dissertation Repository

The purpose of this dissertation was to develop an understanding of, and draw attention to, the health and service access issues faced by trans (transgender, transsexual, or transitioned) Ontarians. This thesis is based on the Trans PULSE Project, a community-based research (CBR) initiative whose goal is to improve the health of trans people. Data collection was carried out between May 2009 and April 2010 using a quantitative survey. Trans participants were recruited through respondent-driven sampling (RDS), a network-based sampling method developed for the recruitment of hidden populations. Weighted prevalence estimates and 95% confidence intervals were calculated for all variables of …

A Survey Of Georgia Adult Protective Services Staff Regarding Elder Abuse Laws And Policies: Determining Training Needs, Judith Kerr

Public Health Theses

Abstract Background: The aging population is a rapidly growing demographic. Isolation and limited autonomy render many of the elderly vulnerable to abuse, neglect and exploitation. As the population grows, so does the need for Adult Protective Services (APS). This study was conducted to examine current knowledge of Georgia older adult protection laws and to identify training opportunities to better prepare the APS workforce in cases detection and intervention. Methods: A primary survey was developed in partnership with the Georgia Division of Aging Services’ leadership to identify key training priority issues APS caseworkers and investigators. A 47-item, electronic questionnaire was delivered …

An Analysis Of Household-Reported Health Status And Socio-Demographic Characteristics Associated With Adolescent Influenza Vaccination Rates In The United States: 2008 National Immunization Survey-Teen, Lindy Liu

Public Health Theses

Background: Influenza is a highly contagious but preventable acute respiratory illness associated with high morbidity. Seasonal influenza affects approximately 20% to 40% of children and adolescents. Annual influenza vaccination is an effective approach to prevent illness but recent studies suggests that adolescents are underutilizing important preventive health services and that influenza vaccination coverage in high risk adolescents is also suboptimal. The purpose of this study was to examine the association between household reported health status and socio-demographic characteristics of U.S. adolescents who reported receiving an influenza vaccination.

Methods: Data from the 2008 National Immunization Survey were assessed examining various demographic …

Delivery Of Asthma Management Services By A Federally Qualified Health Center In An Urban Setting, Tyra T. Buckley

Public Health Theses

As a chronic disease, asthma presents a significant public health challenge nationally and in Georgia. In 2007, over 22 million people, including over 9 million children, had asthma in the United States. In Georgia, 230,000, or 10% of children have asthma, which is more prevalent among children less than 18 years of age than among adults. While asthma affects people of all ages and socioeconomic status, low income and minority populations have the highest asthma morbidity. This has proven to be the case with residents of Neighborhood Planning Unit V (NPU-V), a low-income minority community located in southeast Atlanta. Children …