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Derivation And Validation Of A General Predictive Model For Long Term Risks For Mortality And Invasive Cardiovascular Interventions In Congenital Heart Disease, David A. Danford
Derivation And Validation Of A General Predictive Model For Long Term Risks For Mortality And Invasive Cardiovascular Interventions In Congenital Heart Disease, David A. Danford
Capstone Experience
Introduction. Accurate assessment of prognosis is a key driver of clinical decision making in congenital heart disease (CHD), but is complicated because CHD represents such a diverse collection of conditions. The aim of this investigation is to derive, validate, and calibrate multivariable predictive models for time to surgical or catheter-mediated intervention (INT) in CHD and for time to death in CHD. Methods. 4108 unique subjects were prospectively and consecutively enrolled, and randomized to derivation and validation cohorts. Total follow up was 26,578 patient-years, with 102 deaths and 868 INTs. Accelerated failure time multivariable predictive models for the outcomes, based on …
Factors Affecting The Mortality Rate Of Older Patients With Covid-19 In Nebraska: A Retrospective Cohort Study, Erin Johnson
Factors Affecting The Mortality Rate Of Older Patients With Covid-19 In Nebraska: A Retrospective Cohort Study, Erin Johnson
Capstone Experience
The pandemic spread of COVID-19 is a continued global health emergency. The objectives of this paper were to examine Factors affecting the mortality rate of older patients with COVID-19 in Nebraska. A longitudinal analysis of data gathered from the Nebraska Electronic Disease Surveillance System (NEDSS) was performed. Included were 322 individuals who tested positive for COVID-19 in the month of October 2020. The Kaplan-Meier method was used to estimate the time to death of individuals over the age of 65 after a positive COVID-19 diagnosis and the probability of survival to any given time point. The effect of multiple risk …