Open Access. Powered by Scholars. Published by Universities.®

Public Health Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 9 of 9

Full-Text Articles in Public Health

Designing The Search Trial: Ph250b In Practice, Laura Balzer Sep 2013

Designing The Search Trial: Ph250b In Practice, Laura Balzer

Laura B. Balzer

No abstract provided.


Estimating Effects On Rare Outcomes: Knowledge Is Power, Laura B. Balzer, Mark J. Van Der Laan May 2013

Estimating Effects On Rare Outcomes: Knowledge Is Power, Laura B. Balzer, Mark J. Van Der Laan

Laura B. Balzer

Many of the secondary outcomes in observational studies and randomized trials are rare. Methods for estimating causal effects and associations with rare outcomes, however, are limited, and this represents a missed opportunity for investigation. In this article, we construct a new targeted minimum loss-based estimator (TMLE) for the effect of an exposure or treatment on a rare outcome. We focus on the causal risk difference and statistical models incorporating bounds on the conditional risk of the outcome, given the exposure and covariates. By construction, the proposed estimator constrains the predicted outcomes to respect this model knowledge. Theoretically, this bounding provides …


R Lab 5 - Tmle, Laura Balzer, Maya Petersen, Alexander Luedtke Dec 2012

R Lab 5 - Tmle, Laura Balzer, Maya Petersen, Alexander Luedtke

Laura B. Balzer

No abstract provided.


R Lab 1 - Causal Parameters & Intro R, Laura Balzer, Maya Petersen, Alex Luedtke Dec 2012

R Lab 1 - Causal Parameters & Intro R, Laura Balzer, Maya Petersen, Alex Luedtke

Laura B. Balzer

No abstract provided.


R Lab 3 - Superlearner (Data), Laura Balzer Dec 2012

R Lab 3 - Superlearner (Data), Laura Balzer

Laura B. Balzer

No abstract provided.


R Lab 4 - Iptw (Data), Laura Balzer Dec 2012

R Lab 4 - Iptw (Data), Laura Balzer

Laura B. Balzer

No abstract provided.


R Lab 5 - Tmle (Data), Laura Balzer Dec 2012

R Lab 5 - Tmle (Data), Laura Balzer

Laura B. Balzer

No abstract provided.


R Lab 1 - Intro R & Causal Parameters, Laura Balzer, Maya Petersen, Alex Luedtke Dec 2012

R Lab 1 - Intro R & Causal Parameters, Laura Balzer, Maya Petersen, Alex Luedtke

Laura B. Balzer

No abstract provided.


R Lab 6 - Inference (Data), Laura Balzer Dec 2012

R Lab 6 - Inference (Data), Laura Balzer

Laura B. Balzer

No abstract provided.