Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 6 of 6
Full-Text Articles in Public Health
Molecular Mechanisms Lead To Sex-Specific Covid-19 Prognosis And Targeted Therapies, Thushara Galbadage, Brent M. Peterson, Jeffrey S. Wang, Avishka Jayasekara, Danny A. Ramirez, Joseph Awada, John P. Walsh, Richard S. Gunasekera
Molecular Mechanisms Lead To Sex-Specific Covid-19 Prognosis And Targeted Therapies, Thushara Galbadage, Brent M. Peterson, Jeffrey S. Wang, Avishka Jayasekara, Danny A. Ramirez, Joseph Awada, John P. Walsh, Richard S. Gunasekera
Faculty Articles & Research
Clinical and epidemiological studies have identified male sex as an important risk factor for COVID-19 clinical outcomes and mortality. This raises the question as to how this risk factor can be addressed in the prognosis, clinical management, and the treatment of patients with Coronavirus disease 2019 (COVID-19). Currently, there are no guidelines or protocols to help alter the course of sex-specific COVID-19 prognosis, especially in severe disease presentations. This is partly due to the lack of research studies characterizing the differences in male vs. female host response to the severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) infection and a lack of …
Delayed Interventions, Low Compliance, And Health Disparities Amplified The Early Spread Of Covid-19, Aliea M. Jalali, Sumaia G. Khoury, Jongwon See, Alexis M. Gulsvig, Brent M. Peterson, Richard S. Gunasekera, Gentian Buzi, Jason Wilson, Thushara Galbadage
Delayed Interventions, Low Compliance, And Health Disparities Amplified The Early Spread Of Covid-19, Aliea M. Jalali, Sumaia G. Khoury, Jongwon See, Alexis M. Gulsvig, Brent M. Peterson, Richard S. Gunasekera, Gentian Buzi, Jason Wilson, Thushara Galbadage
Faculty Articles & Research
The United States (US) public health interventions were rigorous and rapid, yet failed to arrest the spread of the Coronavirus Disease 2019 (COVID-19) pandemic as infections spread throughout the US. Many factors have contributed to the spread of COVID-19, and the success of public health interventions depends on the level of community adherence to preventative measures. Public health professionals must also understand regional demographic variation in health disparities and determinants to target interventions more effectively. In this study, a systematic evaluation of three significant interventions employed in the US, and their effectiveness in slowing the early spread of COVID-19 was …
Early Covid-19 Interventions Failed To Replicate St. Louis Vs. Philadelphia Outcomes In The United States, Aliea M. Jalali, Brent M. Peterson, Thushara Galbadage
Early Covid-19 Interventions Failed To Replicate St. Louis Vs. Philadelphia Outcomes In The United States, Aliea M. Jalali, Brent M. Peterson, Thushara Galbadage
Faculty Articles & Research
The Coronavirus disease 2019 (COVID-19) pandemic has elicited an abrupt pause in the United States in multiple sectors of commerce and social activity. As the US faces this health crisis, the magnitude, and rigor of their initial public health response was unprecedented. As a response, the entire nation shutdown at the state-level for the duration of approximately one to three months. These public health interventions, however, were not arbitrarily decided, but rather, implemented as a result of evidence-based practices. These practices were a result of lessons learned during the 1918 influenza pandemic and the city-level non-pharmaceutical interventions (NPIs) taken across …
Systematic Review And Meta-Analysis Of Sex-Specific Covid-19 Clinical Outcomes, Thushara Galbadage, Brent M. Peterson, Joseph Awada, Alison S. Buck, Danny A. Ramirez, Jason Wilson, Richard S. Gunasekera
Systematic Review And Meta-Analysis Of Sex-Specific Covid-19 Clinical Outcomes, Thushara Galbadage, Brent M. Peterson, Joseph Awada, Alison S. Buck, Danny A. Ramirez, Jason Wilson, Richard S. Gunasekera
Faculty Articles & Research
To successfully mitigate the extraordinary devastation caused by the Coronavirus disease 2019 (COVID-19) pandemic, it is crucial to identify important risk factors for this disease. One such neglected health determinant is the sex of the patient. This is an essential clinical characteristic, as it can factor into a patient’s clinical management and preventative measures. Some clinical studies have shown disparities in the proportion between males and females that have more severe clinical outcomes or, subsequently, die from this disease. However, this association has not been unequivocally established. Thus, the purpose of this investigation was to examine the association between male …
Does Covid-19 Spread Through Droplets Alone?, Thushara Galbadage, Brent M. Peterson, Richard S. Gunasekera
Does Covid-19 Spread Through Droplets Alone?, Thushara Galbadage, Brent M. Peterson, Richard S. Gunasekera
Faculty Articles & Research
The world has been in the midst of a swiftly unfolding public health crisis that has turned deadly. The novel coronavirus disease 2019 (COVID-19), has turned out to be a rapidly expanding pandemic affecting the nations of the world. Most governments and their public health authorities worldwide have taken drastic measures to strictly contain the spread of this coronavirus. However, despite the aggressive preventative measures in place, COVID-19 has propagated exponentially across the world. Currently, the accepted mode of disease transmission is by droplets containing the virus. Here we provide epidemiological data in conjunction with biochemical molecular mechanisms of this …
Epidemiological Study Of Covid-19 Modes Of Disease Transmission: With Molecular Basis For Sars-Cov-2 Virulence, Thushara Galbadage, Brent M. Peterson, Richard S. Gunasekera
Epidemiological Study Of Covid-19 Modes Of Disease Transmission: With Molecular Basis For Sars-Cov-2 Virulence, Thushara Galbadage, Brent M. Peterson, Richard S. Gunasekera
Faculty Articles & Research
The world has been embroiled in a deadly and volatile public health crisis. The novel coronavirus disease 2019 (COVID-19), as a pandemic, has been rapidly affecting nations throughout the world with such ferocity that governments and their public health authorities have been forced to take drastic measures to contain the spread. Yet, despite the aggressive preventative measures in place, COVID-19 has propagated exponentially throughout the world. In response, we conducted an epidemiological study evaluating cumulative incidence, incidence rate, and mortality rate of COVID-19 to better understand the potential modes of disease transmission.in select countries experiencing a high burden of the …