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Clinical Epidemiology

Western University

Electronic Thesis and Dissertation Repository

Clinical Epidemiology

Publication Year

Articles 1 - 2 of 2

Full-Text Articles in Public Health

Association Of Post-Traumatic Stress Disorder Exposure And Treatment In Pregnancy With Pregnancy, Obstetric And Neonatal Outcomes, Natalie Zitoun Jun 2023

Association Of Post-Traumatic Stress Disorder Exposure And Treatment In Pregnancy With Pregnancy, Obstetric And Neonatal Outcomes, Natalie Zitoun

Electronic Thesis and Dissertation Repository

A particular condition for which there is a dearth of pregnancy information is Post-Traumatic Stress disorder (PTSD). This thesis aimed to evaluate PTSD exposure and treatment in pregnancy. Our first study was a systematic review, meta-analysis, and GRADE assessment that reported associations between maternal PTSD exposure with pregnancy, obstetric, and neonatal outcomes. Our second study was a prospective evaluation of pregnancy outcomes after prazosin exposure in the first trimester of pregnant patients who were counselled at the Fetal Risk Assessment from Maternal Exposures (FRAME) clinic. Our review and analysis found positive associations between PTSD in pregnancy and some adverse pregnancy …


Developing Artificial Intelligence And Machine Learning To Support Primary Care Research And Practice, Jacqueline K. Kueper Jul 2022

Developing Artificial Intelligence And Machine Learning To Support Primary Care Research And Practice, Jacqueline K. Kueper

Electronic Thesis and Dissertation Repository

This thesis was motivated by the potential to use "everyday data", especially that collected in electronic health records (EHRs) as part of healthcare delivery, to improve primary care for clients facing complex clinical and/or social situations. Artificial intelligence (AI) techniques can identify patterns or make predictions with these data, producing information to learn about and inform care delivery. Our first objective was to understand and critique the body of literature on AI and primary care. This was achieved through a scoping review wherein we found the field was at an early stage of maturity, primarily focused on clinical decision support …