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Clinical Epidemiology

Western University

Electronic Thesis and Dissertation Repository

2014

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Provincially-Funded Insulin Pump Therapy And Glycaemic Control: Real-World Experience In London, Ontario, Selina L. Liu Mar 2014

Provincially-Funded Insulin Pump Therapy And Glycaemic Control: Real-World Experience In London, Ontario, Selina L. Liu

Electronic Thesis and Dissertation Repository

Background: Limited “real-world” evidence exists supporting insulin pump therapy (IPT) benefits in adults with type 1 diabetes mellitus (T1DM).

Methods: A retrospective matched cohort study compared the change in glycated hemoglobin (A1C) and incidence of adverse events before and after IPT start in adults with T1DM at St. Joseph’s Healthcare in London, Ontario started on IPT between September 2008 – August 2011 to those of a matched control cohort. Paired t-tests, McNemar’s test and negative binomial regression were used.

Results: 174 matched pairs were included. At 1 year, glycaemic control significantly improved in IPT users but not in controls—the …