Psychiatry and Psychology Commons^™

Unique Posttraumatic Growth Expression Among Homeless Males Currently Enrolled In Chemical Dependency Treatment, Travis T. Mord

Theses and Graduate Projects

Posttraumatic growth (PTG) has gained considerable research and clinical attention for the past three decades. While the impact of PTG has been well-researched in relation to trauma exposure, medical ailments, or mood related conditions, there are still a number of mental health conditions requiring further analysis. The current study examined the relationship between PTG and key substance use significance indicators, including diagnostic severity of the use disorder and number of previous substance use treatment attempts, among a sample (N = 136) of adult men who were enrolled in a mental illness/chemical dependency (MICD) intensive outpatient program (IOP). This study also …

Neurobiology Of Ptsd In Adults And Children: The Impact Of Stress-Induced Brain Abnormalities Across The Lifespan, Catherine Clover

Undergraduate Honors Theses

In the scholarly community, there is disagreement about the effects of PTSD or chronic stress on the brain of adults and children. Though PTSD or chronic stress are known to negatively affect neurobiological structures, specifically due to prolonged glucocorticoid excess, volumetric discrepancies between traumatized and control groups are not unanimously confirmed. This review sought to address the common understandings in academia of the effects of PTSD on the brains of adults and children. Literature on this topic indicated that, in adults, the hippocampus, cingulate gyrus, and prefrontal cortex bilaterally appeared to decrease in gray matter volume and the corpus callosum …

Physiological Responses Regarding Stress And Trauma: The Freeze Response, Emma Arie Von Holten

UNF Graduate Theses and Dissertations

Fight-or-flight is a commonly known response to threatening situations, but the freeze response is another defensive mechanism that might arise in such situations. There is also evidence that exposure to trauma can impact physiological reactions when defensive mechanisms are not required, such as freezing in response to non-threatening situations. The current study aimed to replicate and expand upon a limited number of previous studies on the human freeze response by implementing measurements of postural sway, heart rate, and infrared thermography while valenced images were shown to participants. Ninety-two participants were recruited from the University of North Florida and participants were …

Treating Comorbid Ptsd And Bpd: A Dialectical Approach, Meredith Pescatello

Intuition: The BYU Undergraduate Journal of Psychology

According to the Biosocial Developmental Model for Borderline Personality Disorder (BPD), individuals with a biological vulnerability (i.e., heightened emotional sensitivity and impulsive tendencies), plus an invalidating environment may develop BPD (Crowell, Beauchaine, & Linehan, 2009). Individuals with BPD are especially difficult to treat, because of their “extreme emotional, behavioral, and cognitive dysregulation” (Crowell, Beauchaine, & Linehan, 2009). Though challenging to treat, BPD can be successfully treated using Dialectical Behavior Therapy (DBT) (Linehan, 1993; Linehan 2015). Similarly, Posttraumatic Stress Disorder (PTSD) is complex and often burnout inducing to treat, because of the intensity of the emotional content related to traumatic events …

Post-Traumatic Stress Disorder: Review Of Dsm Criteria And Functional Neuroanatomy, Cornelius W. Thomas

Marshall Journal of Medicine

The Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria for post-traumatic stress disorder (PTSD) consist of over twenty possible symptoms that can be divided into six broad categories. These categories correlate with specific brain networks that regulate emotions, behaviors, and autonomic function. Normal functioning of these networks depends on two key regions; the prefrontal cortex and the amygdala. The prefrontal cortex provides top-down executive control over amygdala, whereas the amygdala is critical for threat detection and activation of the ‘fight or flight’ response. Events that trigger extreme and/or prolonged fear can cause persisting dysregulation within the prefrontal-amygdala circuit; resulting …

Fear Conditioning And Reconsolidation-Blockade In The Treatment Of Post-Traumatic Stress Disorder In Emergency Responders, Mythili Ananthasayan

Senior Projects Spring 2015

Senior Project submitted to The Division of Social Studies of Bard College.

Prospective Investigation Of A Ptsd Personality Typology Among Individuals With Personality Disorders, Meghan E. Mcdevitt-Murphy, M. Tracie Shea, Shirley Yen, Carlos M. Grilo, Charles A. Sanislow, John C. Markowitz, Andrew E. Skodol

Charles A. Sanislow, Ph.D.

This study investigated the replicability of a previously proposed personality typology of posttraumatic stress disorder (PTSD, and explored stability of cluster membership over a 6-month period. Participants with current PTSD (n = 156) were drawn from the Collaborative Longitudinal Personality Disorders Study (CLPS). The CLPS project tracked a large sample of individuals who met criteria for 1 of 4 target diagnoses (borderline, schizotypal, avoidant, and obsessive-compulsive) and a contrast group of individuals who met criteria for depression but no personality disorder. A cluster analysis using scales from the Schedule of Nonadaptive and Adaptive Personality yielded 3 clusters: “internalizing,” “externalizing,” and …

The Association Of Personality Disorders With The Prospective 7-Year Course Of Anxiety Disorders, Emily B. Ansell, Anthony Pinto, Maria O. Edelen, John C. Markowitz, Charles A. Sanislow, Shirley Yen, Mary C. Zanarini, Andrew E. Skodol, M. Tracie Shea, Leslie C. Morey, John G. Gunderson, Thomas H. Mcglashan, Carlos M. Grilo

Charles A. Sanislow, Ph.D.

Background. This study prospectively examined the natural clinical course of six anxiety disorders over 7 years of follow-up in individuals with personality disorders (PDs) and/or major depressive disorder. Rates of remission, relapse, new episode onset and chronicity of anxiety disorders were examined for specific associations with PDs.

Method. Participants were 499 patients with anxiety disorders in the Collaborative Longitudinal Personality Disorders Study, who were assessed with structured interviews for psychiatric disorders at yearly intervals throughout 7 years of follow-up. These data were used to determine probabilities of changes in disorder status for social phobia (SP), generalized anxiety disorder (GAD), obsessive-compulsive …

Trajectories Of Ptsd And Substance Use Disorders In A Longitudinal Study Of Personality Disorders, Meghan E. Mcdevitt-Murphy, Gilbert R. Parra, M. Tracie Shea, Shirley Yen, Carlos M. Grilo, Charles A. Sanislow, Thomas H. Mcglashan, John G. Gunderson, Andrew E. Skodol, John C. Markowitz

Charles A. Sanislow, Ph.D.

The Effects Of Child Sexual Abuse And Posttraumatic Stress On Levels Of Self-Efficacy, Lary L. Anderson

Graduate Theses

Sexually abused children often develop posttraumatic stress disorder, a distressing and potentially debilitating condition that renders children to feelings of helplessness. Past studies have explored these effects in adults concerning sexual abuse, health issues, war, and natural disaster but not much research has been done for children. This study examined childhood sexual abuse, PTSD, and the relation that exists with self-efficacy. Thirty-nine children, 7 males and 32 females, participated in the study. The ages ranged from age eight through age eighteen, with a mean age of 12.5. Each participant was tested for levels of PTSD, using the Trauma Check list …

Psychophysiological Reactivity To Traumatic And Abandonment Scripts In Borderline Personality And Posttraumatic Stress Disorders: A Preliminary Report, Christian G. Schmahl, Bernet M. Elzinga, Ulrich W. Ebner, Timothy Simms, Charles A. Sanislow, Eric Vermetten, Thomas H. Mcglashan, J. Douglas Bremner

Charles A. Sanislow, Ph.D.

Borderline personality disorder (BPD) is a highly prevalent and disabling condition linked to early stressors including traumatic abuse and abandonment. While much work has addressed traumatic events in childhood, little is known about the biological sequelae of BPD including how this disorder may be differentiated from other stressrelated disorders such as posttraumatic stress disorder (PTSD). The purpose of this study was to investigate psychophysiological effects of different types of stressful reminders in BPD and in PTSD. Psychophysiological measures including heart rate, skin conductance responses, systolic and diastolic blood pressure in response to standardized neutral scripts, and personalized scripts of traumatic …

Amygdala Hyperreactivity In Borderline Personality Disorder: Implications For Emotional Dysregulation, Nelson H. Donegan, Charles A. Sanislow, Hilary P. Blumberg, Robert K. Fulbright, Cheryl Lacadie, Pawel Skudlarski, John C. Gore, Ingrid R. Olson, Thomas H. Mcglashan, Bruce E. Wexler

Charles A. Sanislow, Ph.D.

BACKGROUND: Disturbed interpersonal relations and emotional dysregulation are fundamental aspects of borderline personality disorder (BPD). The amygdala plays important roles in modulating vigilance and generating negative emotional states and is often abnormally reactive in disorders of mood and emotion. The aim of this study was to assess amygdala reactivity in BPD patients relative to normal control subjects. We hypothesized that amygdala hyperreactivity contributes to hypervigilance, emotional dysregulation, and disturbed interpersonal relations in BPD.

METHODS: Using functional magnetic resonance imaging, we examined neural responses to 20-sec blocks of neutral, happy, sad, and fearful facial expression (or a fixation point) in 15 …

Clinical Features And Impairment In Women With Borderline Personality Disorder (Bpd) With Post-Traumatic Stress Disorder (Ptsd), Bpd Without Ptsd, And Other Personality Disorders With Ptsd, Caron Zlotnick, Dawn M. Johnson, Shirley Yen, Cynthia Battle, Charles A. Sanislow, Andrew E. Skodol, Carlos M. Grilo, Thomas H. Mcglashan, John G. Gunderson, Donna S. Bender, Mary C. Zanarini, M. Tracie Shea

Charles A. Sanislow, Ph.D.

The aims of this study were to examine differences in clinical features, impairment, and types of childhood traumas among women with borderline personality disorder (BPD), women with BPD and posttraumatic stress disorder (PTSD), and those with other personality disorders and PTSD. Using baseline data from the Collaborative Longitudinal Study of Personality Disorders, 186 women were divided into 3 groups (BPD+PTSD, BPD, PTSD), based on structured diagnostic interviews for Axis I and Axis II disorders and compared on selected clinical variables. The additional diagnosis of PTSD in borderline women did not significantly increase the degree of borderline pathology and psychiatric morbidity …

Rape Survivors: The Effects Of Post-Traumatic Stress And Locus Of Control On The Hoping Process, David Lester Rhoads

Graduate Theses

The current study examined the relationship between hope. Post Traumatic Stress Disorder, and locus of control in a sample, of 18 rape survivors and 18 non-raped females over 18 years of age. Instruments utilized were Herth Hope Scale, Structured Interview for Post Traumatic Stress Disorder, Impact of Events, and Locus of Control Scales. It was hypothesized that rape survivors would exhibit a lower level of hope, higher levels of Post Traumatic Stress Disorder, and an external locus of control. Independent t-tests revealed that rape trauma impacts Post Traumatic Stress Disorder. Independent t-tests were inconclusive among the hope, impact of events, …

Posttraumatic Stress Disorder In Sexually Abused Children And Implications For Therapy, Robbie Jones

Graduate Theses

This study examined the symptoms of posttraumatic stress disorder (PTSD) in sexually abused children. Sixty-seven children volunteered to participate in this study. Of the 67 children, 33 (26 female and 7 male) were sexually abused and 34 (22 female and 12 male) were non-sexually abused. Several instruments were employed to assess the severity of the symptoms of PTSD including the Children's PTSD Inventory, the Child Behavior Checklist, and the Children's Depression Inventory, as well as others. The results of this study showed that sexually abused children have more symptoms of PTSD than non-sexually abused children. Early diagnosis and treatment of …