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Full-Text Articles in Psychiatry and Psychology

Convergent Roles Of De Novo Mutations And Common Variants In Schizophrenia In Tissue-Specific And Spatiotemporal Co-Expression Network, Peilin Jia, Xiangning Chen, Ayman H. Fanous, Zhongming Zhao May 2018

Convergent Roles Of De Novo Mutations And Common Variants In Schizophrenia In Tissue-Specific And Spatiotemporal Co-Expression Network, Peilin Jia, Xiangning Chen, Ayman H. Fanous, Zhongming Zhao

Psychology Faculty Research

Genetic components susceptible to complex disease such as schizophrenia include a wide spectrum of variants, including common variants (CVs) and de novo mutations (DNMs). Although CVs and DNMs differ by origin, it remains elusive whether and how they interact at the gene, pathway, and network levels that leads to the disease. In this work, we characterized the genes harboring schizophrenia-associated CVs (CVgenes) and the genes harboring DNMs (DNMgenes) using measures from network, tissue-specific expression profile, and spatiotemporal brain expression profile. We developed an algorithm to link the DNMgenes and CVgenes in spatiotemporal brain co-expression networks. DNMgenes tended to have central …


The Effect Of Choice On Throwing Speed In Baseball Players, Brooke Andrea Boyd May 2018

The Effect Of Choice On Throwing Speed In Baseball Players, Brooke Andrea Boyd

UNLV Theses, Dissertations, Professional Papers, and Capstones

Incidental choices have been identified as one way to support the need for autonomy. The purpose of this study was to determine if choice in type and color of wrist tape would influence throwing speed in baseball players. Participants were experienced male baseball players from a local high school. All participants performed 10 throws under choice and no-choice conditions. Throwing speed did not differ as a function of choice versus no choice. Possible explanations and limitations of the present study are discussed.


Mate Preferences Among Single Mothers, Carol Yvette Franco May 2018

Mate Preferences Among Single Mothers, Carol Yvette Franco

UNLV Theses, Dissertations, Professional Papers, and Capstones

As individuals become parents, they shift time and energy towards parenting to ensure the survival and wellbeing of their offspring. However, it is not uncommon for a romantic partnership between parents to dissolve, which may lead a single mother to pursue a new partner in the future. But how does having a dependent child influence whom she will choose for her new partner? And how will resource availability and assistance from family influence the decisions she makes? A significant amount of research has been conducted on female mate preferences in the United States and elsewhere, yet little is specifically focused …


Nativity Differences In Stress Among Asian And Pacific Islander American Women, Brittany N. Morey, Gilbert C. Gee, Salma Shariff-Marco, Gem M. Le, Alison J. Canchola, Juan Yang, Laura Allen, Sandra Lee, Roxanna Bautista, Trish Quema La Chica, Winston Tseng, Pancho Chang, Scarlett Lin Gomez May 2018

Nativity Differences In Stress Among Asian And Pacific Islander American Women, Brittany N. Morey, Gilbert C. Gee, Salma Shariff-Marco, Gem M. Le, Alison J. Canchola, Juan Yang, Laura Allen, Sandra Lee, Roxanna Bautista, Trish Quema La Chica, Winston Tseng, Pancho Chang, Scarlett Lin Gomez

Journal of Health Disparities Research and Practice

According to the Stress Process Theory, people who are marginalized in society encounter more stress than those in more advantaged positions. Immigrants are one such marginalized group in the United States (US) who may experience greater psychological stress than their US-born counterparts due to (1) severing of social ties; (2) social disadvantage and marginalization; and (3) adaptation to a new environment. This study examines the disparity in stress by nativity, and how social factors contribute to this disparity for Asian and Pacific Islander (API) women. Data come from the Asian Community Health Initiative, which included a sample of 291 foreign-born …


Inflammation As A Central Mechanism In Alzheimer's Disease, Jefferson W. Kinney, Shane M. Bemiller, Andrew S. Murtishaw, Amanda M. Leisgang, Arnold M. Salazar, Bruce T. Lamb Jan 2018

Inflammation As A Central Mechanism In Alzheimer's Disease, Jefferson W. Kinney, Shane M. Bemiller, Andrew S. Murtishaw, Amanda M. Leisgang, Arnold M. Salazar, Bruce T. Lamb

Psychology Faculty Research

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is characterized by cognitive decline and the presence of two core pathologies, amyloid β plaques and neurofibrillary tangles. Over the last decade, the presence of a sustained immune response in the brain has emerged as a third core pathology in AD. The sustained activation of the brain's resident macrophages (microglia) and other immune cells has been demonstrated to exacerbate both amyloid and tau pathology and may serve as a link in the pathogenesis of the disorder. In the following review, we provide an overview of inflammation in AD and a detailed …