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Psychiatry and Psychology Commons

Open Access. Powered by Scholars. Published by Universities.®

Nursing

2015

University of Nebraska Medical Center

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Full-Text Articles in Psychiatry and Psychology

Identification Of Candidate Genes For Psychological Resilience To Develop An Additive Genetic Resilience Index: An Integrative Review, Kosuke Niitsu, Julia F. Houfek Apr 2015

Identification Of Candidate Genes For Psychological Resilience To Develop An Additive Genetic Resilience Index: An Integrative Review, Kosuke Niitsu, Julia F. Houfek

Posters and Presentations: College of Nursing

Problem: Most individuals experience at least one potentially traumatic event (PTE), such as tornado, in their lifetime. When exposed to PTEs, some individuals are more vulnerable to psychopathology, such as Posttraumatic Stress Disorder (PTSD). In contrast, other individuals are better able to cope with PTEs and maintain their psychological health. Such individuals are often described as psychologically resilient. Resilience is heritable, influenced by multiple genes including the Serotonin-Transporter-Linked Polymorphic Region (5-HTTLPR), the most studied candidate gene. Because resilience is polygenic, it is important to consider the influence of multiple genes in addition to 5-HTTLPR when studying the heritable component of …