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Articles 1 - 30 of 37
Full-Text Articles in Other Medicine and Health Sciences
Likely Community Transmission Of Covid-19 Infections Between Neighboring, Persistent Hotspots In Ontario, Canada, Ben C. Shirley, Eliseos J. Mucaki, Peter Rogan
Likely Community Transmission Of Covid-19 Infections Between Neighboring, Persistent Hotspots In Ontario, Canada, Ben C. Shirley, Eliseos J. Mucaki, Peter Rogan
Biochemistry Publications
Introduction: This study aimed to produce community-level geo-spatial mapping of confirmed COVID-19 cases in Ontario Canada in near real-time to support decision-making. This was accomplished by area-to-area geostatistical analysis, space-time integration, and spatial interpolation of COVID-19 positive individuals.
Methods: COVID-19 cases and locations were curated for geostatistical analyses from March 2020 through June 2021, corresponding to the first, second, and third waves of infections. Daily cases were aggregated according to designated forward sortation area (FSA), and postal codes (PC) in municipal regions Hamilton, Kitchener/Waterloo, London, Ottawa, Toronto, and Windsor/Essex county. Hotspots were identified with area-to-area tests including Getis-Ord Gi*, Global …
Are Polypills A Viable Option To Improve Health Outcomes In Those With Cardiovascular Disease?, Alexander Voytovich, Cara Mckee
Are Polypills A Viable Option To Improve Health Outcomes In Those With Cardiovascular Disease?, Alexander Voytovich, Cara Mckee
Physician Assistant Capstones, 2020-current
Objective: Does the use of polypill therapy improve systolic blood pressure and low-density lipoprotein cholesterol (LDL-C) levels more than usual care in adults with established cardiovascular disease (CVD) or with 10-year atherosclerotic cardiovascular disease risk >10%. Design: Systematic literature review. Methods: Searches were performed in PubMed and UpToDate using the following search terms polypill and cardiovascular. Other limits included: randomized control trials, adults, published in the last 10 years, LDL-C and systolic blood pressure. Results: Analysis of articles to ensure similar design, intervention and fit with the other inclusion/exclusion criteria yielded three studies: Labefer et al, Muñoz et al, and …
Quality Evaluation Of Consumer Health Information Websites Found On Google Using Discern, Craap, And Honcode, Ivan A. Portillo, Catherine V. Johnson, Scott Y. Johnson
Quality Evaluation Of Consumer Health Information Websites Found On Google Using Discern, Craap, And Honcode, Ivan A. Portillo, Catherine V. Johnson, Scott Y. Johnson
Library Articles and Research
Online health misinformation is a growing problem, and health information professionals and consumers would benefit from an evaluation of health websites for reliability and trustworthiness. Terms from the Google COVID-19 Search Trends dataset were searched on Google to determine the most frequently appearing consumer health information websites. The quality of the resulting top five websites was evaluated. The top five websites that appeared most frequently were WebMD, Mayo Clinic, Healthline, MedlinePlus, and Medical News Today, respectively. All websites, except Medline Plus, received HONcode certification. Based on DISCERN and CRAAP scores, MedlinePlus was found to be the most reliable health website.
Health Information Management Practice In Health Care Delivery System: A Case Study Of University Of Medical Sciences Teaching Hospital Complex, Ondo, Ondo State, Nigeria, Tajudeen Temitayo Adebayo Dr, Sunday Ayo Gbabe Mr
Health Information Management Practice In Health Care Delivery System: A Case Study Of University Of Medical Sciences Teaching Hospital Complex, Ondo, Ondo State, Nigeria, Tajudeen Temitayo Adebayo Dr, Sunday Ayo Gbabe Mr
Library Philosophy and Practice (e-journal)
The aim of this research work is to ascertain the relevance of health information management practice in health care delivery system. This research reviewed past and presents literature that of relevance to this research topic. Descriptive survey research design was adopted. Questionnaire was used to collect necessary information through probability sampling method and specifically the simple random sampling. Fifty (50) questionnaires were distributed to Health Information Practitioners at University of Medical Sciences Teaching Hospital Complex, Ondo and all the fifty questionnaires were retrieved for data analysis. It has been proved that HIM practice plays a very vital role in effective …
Clinical Coding And Indexing As Indispensable Tool In Health Care, Teaching And Research: A Case Study Of Obafemi Awolowo Teaching Hospital Complex (Oauthc) Ile-Ife, Osun State, Tajudeen Temitayo Adebayo Dr, Sadiq Anifat Afolabi Mrs, Soladayo Olabisi Fajuyigbe Mrs, Olayiwola Kayode Adepoju Dr, Michael Segun Omole Dr
Clinical Coding And Indexing As Indispensable Tool In Health Care, Teaching And Research: A Case Study Of Obafemi Awolowo Teaching Hospital Complex (Oauthc) Ile-Ife, Osun State, Tajudeen Temitayo Adebayo Dr, Sadiq Anifat Afolabi Mrs, Soladayo Olabisi Fajuyigbe Mrs, Olayiwola Kayode Adepoju Dr, Michael Segun Omole Dr
Library Philosophy and Practice (e-journal)
Clinical coding and indexing is the process by which medical procedure and diagnoses are represented and displayed by universal code number. It is a system that plays a key role in modern healthcare and also allow statistical analyses of diseases and treatment, diagnoses related group, reimbursement, easier observance and tracking of epidemic and production events. The study therefore aimed at examining coding and indexing as indispensable tool in healthcare, teaching and research; a case study of OAUTHC Ile-Ife, Osun State.
The target population was 152 health records officer in OAUTHC, Ile-Ife. A cross-sectional research method was adopted. Data was collected …
Scoping Review: The Empowerment Of Alzheimer’S Disease Caregivers With Mhealth Applications, Eunhee Kim, Andrius Baskys, Anandi V. Law, Moom R. Roosan, Yan Li, Don Roosan
Scoping Review: The Empowerment Of Alzheimer’S Disease Caregivers With Mhealth Applications, Eunhee Kim, Andrius Baskys, Anandi V. Law, Moom R. Roosan, Yan Li, Don Roosan
Pharmacy Faculty Articles and Research
Alzheimer’s Disease (AD) is one of the most prevalent neurodegenerative chronic diseases. As it progresses, patients become increasingly dependent, and their caregivers are burdened with the increasing demand for managing their care. Mobile health (mHealth) technology, such as smartphone applications, can support the need of these caregivers. This paper examines the published academic literature of mHealth applications that support the caregivers of AD patients. Following the PRISMA for scoping reviews, we searched published literature in five electronic databases between January 2014 and January 2021. Twelve articles were included in the final review. Six themes emerged based on the functionalities provided …
An Intersectional Approach To Time Poverty: A Pilot Study Of Time Poverty And Black Women’S Perceived Health Based On Semi-Structured Interviews, Lauriane Ngaya Fonkou
An Intersectional Approach To Time Poverty: A Pilot Study Of Time Poverty And Black Women’S Perceived Health Based On Semi-Structured Interviews, Lauriane Ngaya Fonkou
McNair Scholars Program
The term “time poor” describes people disproportionately burdened by responsibilities and inflexible work schedules resulting in little to no discretionary time. Time poverty was brought to my attention via the social media app TikTok where Black women creators expressed how time poverty affects them. Given that Black women are an especially vulnerable population in terms of health, I became curious about the relationship between time poverty and Black women’s health. However, the existing sociomedical science literature on time poverty does NOT adequately account for Black women’s subjectivity because the research considers mediators of class OR gender OR race but does …
Covid-19 Impact On Radiology Students’ Distance Learning (Summer 2021), Mary Lee, Jason Chan, Cheryann Jackson-Holmes, Renzo Marmolejo, Zoya Vinokur
Covid-19 Impact On Radiology Students’ Distance Learning (Summer 2021), Mary Lee, Jason Chan, Cheryann Jackson-Holmes, Renzo Marmolejo, Zoya Vinokur
Publications and Research
The Radiological Technology students have adjusted from the urgent distance learning that was enacted in the Spring of 2020, to the hybrid distance learning that is currently in place. This hybrid distance learning is the same way the incoming class of radiological technology students were taught. Both cohorts of students were tracked over the year by online anonymous surveys. We wanted to know how students were adapting to distance learning, if their focus and motivation varied over the course of the year due to changing pandemic conditions. For the students that were working, what impact did it have on their …
Developing A Practical Application Of The Isometric Squat And Surface Electromyography, David Phillips, Angelic Rose Del Vecchio, Kevin Carroll, Evan L. Matthews
Developing A Practical Application Of The Isometric Squat And Surface Electromyography, David Phillips, Angelic Rose Del Vecchio, Kevin Carroll, Evan L. Matthews
Department of Exercise Science and Physical Education Scholarship and Creative Works
Electromyography (EMG) is a research tool used in gait analysis, muscle coordination evaluation, clinical evaluation and sports techniques. Electromyography can provide an insight into neural adaptations, cross education effects, bilateral contraction deficiencies, and antagonist activity in exercise-related movements. While there are clear benefits to using EMG in exercise-related professions, accessibility, cost, and difficulty interpreting the data limit its use in strength and clinical settings. We propose a practical EMG assessment using the isometric squat to identify compensatory activation patterns and report early observations. Ten healthy participants were recruited. Participants performed a 2-min isometric handgrip protocol and an isometric squat protocol. …
Vegetarian Diets, Maybe Not As Healthy As You Think, Darryl Goh, Debbie Chan, Merson Hoo, Ian Wong
Vegetarian Diets, Maybe Not As Healthy As You Think, Darryl Goh, Debbie Chan, Merson Hoo, Ian Wong
Introduction to Research Methods RSCH 202
Many are approaching vegetarianism as a viable diet option in recent years, presuming that adopting a vegetarian diet would provide health benefits. This paper explores the possibilities of physical and mental effects that vegetarianism may have on humans and its extent by the use of regression analysis. To measure the possible impacts vegetarian diets may hold on both the physiology and physical aspects of humans, we have utilized the measures of life expectancy and prevalence of depression respectively. Cross-sectional data were examined from sources such as the World Health Organization, Our World In Data and the World Bank, with figures …
The Effects Of Mapk Signaling On The Development Of Cerebellar Granule Cells, Kerry Morgan
The Effects Of Mapk Signaling On The Development Of Cerebellar Granule Cells, Kerry Morgan
University Scholar Projects
The granule cells are the most abundant neuronal type in the human brain. Rapid proliferation of granule cell progenitors results in dramatic expansion and folding of the cerebellar cortex during postnatal development. Mis-regulation of this proliferation process causes medulloblastoma, the most prevalent childhood brain tumor. In the developing cerebellum, granule cells are derived from Atoh1-expressing cells, which arise from the upper rhombic lip (the interface between the roof plate and neuroepithelium). In addition to granule cells, the Atoh1 lineage also gives rise to different types of neurons including cerebellar nuclei neurons. In the current study, I have investigated the …
Headache And Its Association With Adhd/Add And Stimulant Medication, Claire Nitzsche
Headache And Its Association With Adhd/Add And Stimulant Medication, Claire Nitzsche
Honors Scholar Theses
Years of research has shown that headache (in terms of frequency, duration, and severity) is perpetuated by dysregulation of lifestyle behaviors such as sleep habits, eating habits, level of stress, physical activity etc. Our project aims to explore the potential combined and independent impacts that having ADHD/ADD and taking stimulant drugs have on disrupting one’s lifestyle and examine whether dysregulated lifestyle behaviors contribute to one’s headache experience. No research has investigated how both ADHD/ADD and stimulant drug use effect headache experience. In this cross-sectional study, 177 UConn undergraduate students completed a 10-minute survey regarding lifestyle behaviors and headache experience. Participants …
A Survey Of Slp Graduate Students Pre- And Post-Telepractice Training During The Covid-19 Pandemic, Kelly Allison Frost
A Survey Of Slp Graduate Students Pre- And Post-Telepractice Training During The Covid-19 Pandemic, Kelly Allison Frost
Masters Theses & Specialist Projects
Many university programs in speech-language pathology who offer clinical training as part of their graduate program, transitioned to a telepractice service delivery model in response to the COVID-19 pandemic. The purpose of the current research project was to survey graduate student opinions and perspectives on the telepractice service delivery model before and after training. Graduate students enrolled in a SLP distance program at WKU participated in a summer clinical internship and were asked to complete pre- and post-surveys about their remote clinical experience. Pre- and postsurveys were completed by 27 graduate students who were enrolled in the summer clinical internship …
Assistive Technology: A Consideration For Increased Engagement, Terri Grundy
Assistive Technology: A Consideration For Increased Engagement, Terri Grundy
Occupational Therapy Faculty Scholarship
Technology abounds. There is no doubt that it has made life easier in many ways, but when does technology become assistive technology (AT)? National legislation that has solidified this as an area of practice, but what processes can we use to help determine appropriate technology tools for our clients? How can we minimize AT abandonment? Review of these and other issues related to the use of assistive technology.
Employment-Student To Practitioner, Terri Grundy
Employment-Student To Practitioner, Terri Grundy
Occupational Therapy Faculty Scholarship
Many job openings generate dozens of candidates seeking employement. New practitioners need to be aware of how to navigate this process and things they can do to open doors for consideration. Topics for discussion include writing cover letters and resumes that get read, interviewing - actions to take and pitfalls to avoid, tips for networking and identifying mentors and using social media to your advantage, not disadvantage.
Surgical Patients’ Hospital Experience Scores: Neighborhood Context Conceptual Framework, Ashley Wendell Kranjac, Dinko Kranjac, Michelle A. Fortier, Pat Patton, Brad Giafaglione, Zeev N. Kain
Surgical Patients’ Hospital Experience Scores: Neighborhood Context Conceptual Framework, Ashley Wendell Kranjac, Dinko Kranjac, Michelle A. Fortier, Pat Patton, Brad Giafaglione, Zeev N. Kain
Sociology Faculty Articles and Research
Objective:
Through geocoding the physical residential address included in the electronic medical record to the census tract level, we present a novel model for concomitant examination of individual patient-related and residential context-related factors that are associated with patient-reported experience scores.
Summary Background Data:
When assessing patient experience in the surgical setting, researchers need to examine the potential influence of neighborhood-level characteristics on patient experience-of-care ratings.
Methods:
We geocoded the residential address included in the electronic medical record (EMR) from a tertiary care facility to the census tract level of Orange County, CA. We then linked each individual record to the …
The Feasibility Of Renewable Natural Gas In New Jersey, Anneliese Dyer, Amelia Christine Miller, Brianna Chandra, Juan Galindo Maza, Carley Tran, Justin Bates, Vicky Olivier, Amy Tuininga
The Feasibility Of Renewable Natural Gas In New Jersey, Anneliese Dyer, Amelia Christine Miller, Brianna Chandra, Juan Galindo Maza, Carley Tran, Justin Bates, Vicky Olivier, Amy Tuininga
Publications
With traditional natural gas being one of the top options for heating in the United States and the present threat of climate change, there is a demand for an alternative clean fuel source. A Renewable Natural Gas Implementation Decision-Making Conceptual Model was created to provide a framework for considering the feasibility of renewable natural gas (RNG) projects and applied to New Jersey, specifically investigating landfills and wastewater treatment plants (WWTPs). Data from the US EPA’s Landfill Methane Outreach Program and New Jersey’s Department of Environmental Protection Sewage Sludge databases were used to identify seven landfills and 22 WWTPs as possible …
Perceived Discrimination During The Childbirth Hospitalization And Postpartum Visit Attendance And Content: Evidence From The Listening To Mothers In California Survey, Laura B. Attanasio, Brittany L. Ranchoff, Kimberley H. Geissler
Perceived Discrimination During The Childbirth Hospitalization And Postpartum Visit Attendance And Content: Evidence From The Listening To Mothers In California Survey, Laura B. Attanasio, Brittany L. Ranchoff, Kimberley H. Geissler
Public Health Department Faculty Publication Series
Objective Postpartum visits are an important opportunity to address ongoing maternal health. Experiences of discrimination in healthcare can impact healthcare use, including postpartum visits. However, it is unknown whether discrimination is associated with postpartum visit content. This study aimed to examine the relationship between perceived discrimination during the childbirth hospitalization and postpartum visit attendance and content. Research design Data were from Listening to Mothers in California, a population-based survey of people with a singleton hospital birth in California in 2016. Adjusted logistic regression models estimated the association between perceived discrimination during the childbirth hospitalization and 1) postpartum visit attendance, and …
The Effect Of Remuneration Schedule On Data Completion And Retention In The Pregnancy Eating Attributes Study (Peas), Ndeah Terry, Leah M. Lipsky, Anna Maria Siega-Riz, Aiyi Liu, Tonja R. Nansel
The Effect Of Remuneration Schedule On Data Completion And Retention In The Pregnancy Eating Attributes Study (Peas), Ndeah Terry, Leah M. Lipsky, Anna Maria Siega-Riz, Aiyi Liu, Tonja R. Nansel
Public Health Department Faculty Publication Series
Maximizing data completion and study retention is essential in population research. This study examined the effect of remuneration schedule and data collection modality on data completion and retention in the Pregnancy Eating Attributes Study cohort. Participants (n = 458) completed online surveys and attended six in-person study visits. Initially, remuneration was a prespecified amount per visit, then was changed mid-study to be prorated based on the number of forms completed. Additionally, survey data collection modality was changed to in-person at the sixth study visit. In this secondary data analysis, there was no effect of remuneration schedule on withdrawal rates or …
Accelerated Clearing And Molecular Labeling Of Biological Tissues Using, Joseph Dwyer, M Desmond Ramirez, Paul S. Katz, Rolf O. Karlstrom, Joseph Bergan
Accelerated Clearing And Molecular Labeling Of Biological Tissues Using, Joseph Dwyer, M Desmond Ramirez, Paul S. Katz, Rolf O. Karlstrom, Joseph Bergan
Psychological and Brain Sciences Faculty Publication Series
Techniques used to clear biological tissue for fluorescence microscopy are essential to connect anatomical principles at levels ranging from subcellular to the whole animal. Here we report a simple and straightforward approach to efficiently render opaque tissue samples transparent and show that this approach can be modified to rapidly label intact tissue samples with antibodies for large volume fluorescence microscopy. This strategy applies a magnetohydrodynamic (MHD) force to accelerate the removal of lipids from tissue samples at least as large as an intact adult mouse brain. We also show that MHD force can be used to accelerate antibody penetration into …
Mothers' Sleep Deficits And Cognitive Performance: Moderation By Stress And Age, Kirby Deater-Deckard, Mamatha Chary, Maureen E. Mcquillan, Angela D. Staples, John E. Bates
Mothers' Sleep Deficits And Cognitive Performance: Moderation By Stress And Age, Kirby Deater-Deckard, Mamatha Chary, Maureen E. Mcquillan, Angela D. Staples, John E. Bates
Psychological and Brain Sciences Faculty Publication Series
There are well-known associations between stress, poor sleep, and cognitive deficits, but little is known about their interactive effects, which the present study explored in a sample of mothers of toddlers. Since certain types of cognitive decline start during the 20s and continue into later ages, we also explored whether mothers' age interacted with stress and sleep in the prediction of cognitive functioning. We hypothesized that poorer sleep [measured using one week of 24-hour wrist actigraphy data] and having more chronic stressors [e.g., life events, household chaos, work/family role conflict] would be linked with poorer cognitive performance [both executive function …
Association Between Household Air Pollution And Child Mortality In Myanmar Using A Multilevel Mixed-Effects Poisson Regression With Robust Variance, Juwel Rana, Rakibul M. Islam, Md Nuruzzaman Khan, Razia Aliani, Youssef Oulhote
Association Between Household Air Pollution And Child Mortality In Myanmar Using A Multilevel Mixed-Effects Poisson Regression With Robust Variance, Juwel Rana, Rakibul M. Islam, Md Nuruzzaman Khan, Razia Aliani, Youssef Oulhote
Biostatistics and Epidemiology Faculty Publications Series
Household air pollution (HAP) from solid fuel use (SFU) for cooking is a major public health threat for women and children in low and middle-income countries. This study investigated the associations between HAP and neonatal, infant, and under-five child mortality in Myanmar. The study consisted of 3249 sample of under-five children in the households from the first Myanmar Demographic and Health Survey 2016. Fuel types and levels of exposure to SFU (no, moderate and high) were proxies for HAP. We estimated covariate-adjusted relative risks (aRR) of neonatal, infant, and under-five child mortality with 95% confidence intervals, accounting for the survey …
The Global Viralization Of Policies To Contain The Spreading Of The Covid-19 Pandemic: Analyses Of School Closures And First Reported Cases, José Ignacio Nazif-Muñoz, Sebastián Peña, Youssef Oulhote
The Global Viralization Of Policies To Contain The Spreading Of The Covid-19 Pandemic: Analyses Of School Closures And First Reported Cases, José Ignacio Nazif-Muñoz, Sebastián Peña, Youssef Oulhote
Biostatistics and Epidemiology Faculty Publications Series
Background On January 30(th) 2020, the World Health Organization (WHO) declared a international health emergency due to the unprecedented phenomenon of COVID-19. After this declaration countries swiftly implemented a variety of health policies. In this work we examine how rapid countries responded to this pandemic using two events: the day in which the first case of COVID-19 was reported, and first day in which countries used school closure as one of the measures to avoid outbreaks. We also assessed how countries' health systems, globalization, economic development, political systems, and economic integration to China, Republic of Korea and Italy increased the …
Characteristics Of Hiv Seroconverters In The Setting Of Universal Test And Treat: Results From The Search Trial In Rural Uganda And Kenya, Marilyn N. Nyabuti, Maya L. Petersen, Elizabeth A. Bukusi, Moses R. Kamya, Florence Mwangwa, Jane Kabami, Norton Sang, Edwin D. Charlebois, Laura B. Balzer
Characteristics Of Hiv Seroconverters In The Setting Of Universal Test And Treat: Results From The Search Trial In Rural Uganda And Kenya, Marilyn N. Nyabuti, Maya L. Petersen, Elizabeth A. Bukusi, Moses R. Kamya, Florence Mwangwa, Jane Kabami, Norton Sang, Edwin D. Charlebois, Laura B. Balzer
Biostatistics and Epidemiology Faculty Publications Series
Background Additional progress towards HIV epidemic control requires understanding who remains at risk of HIV infection in the context of high uptake of universal testing and treatment (UTT). We sought to characterize seroconverters and risk factors in the SEARCH UTT trial (NCT01864603), which achieved high uptake of universal HIV testing and ART coverage in 32 communities of adults (>= 15 years) in rural Uganda and Kenya. Methods In a pooled cohort of 117,114 individuals with baseline HIV negative test results, we described those who seroconverted within 3 years, calculated gender-specific HIV incidence rates, evaluated adjusted risk ratios (aRR) for …
Racial And Geographic Variation In Effects Of Maternal Education And Neighborhood-Level Measures Of Socioeconomic Status On Gestational Age At Birth: Findings From The Echo Cohorts, Anne L. Dunlop, Alicynne Glazier Essalmi, Lyndsay Alvalos, Carrie Breton, Carlos A. Camargo, Whitney J. Cowell, Dana Dabelea, Stephen R. Dager, Cristiane Duarte, Ken Kleinman
Racial And Geographic Variation In Effects Of Maternal Education And Neighborhood-Level Measures Of Socioeconomic Status On Gestational Age At Birth: Findings From The Echo Cohorts, Anne L. Dunlop, Alicynne Glazier Essalmi, Lyndsay Alvalos, Carrie Breton, Carlos A. Camargo, Whitney J. Cowell, Dana Dabelea, Stephen R. Dager, Cristiane Duarte, Ken Kleinman
Biostatistics and Epidemiology Faculty Publications Series
Preterm birth occurs at excessively high and disparate rates in the United States. In 2016, the National Institutes of Health (NIH) launched the Environmental influences on Child Health Outcomes (ECHO) program to investigate the influence of early life exposures on child health. Extant data from the ECHO cohorts provides the opportunity to examine racial and geographic variation in effects of individual- and neighborhood-level markers of socioeconomic status (SES) on gestational age at birth. The objective of this study was to examine the association between individual-level (maternal education) and neighborhood-level markers of SES and gestational age at birth, stratifying by maternal …
Altered Physiology Of Gastrointestinal Vagal Afferents Following Neurotrauma, Emily N. Blanke, Gregory M. Holmes, Emily M. Besecker
Altered Physiology Of Gastrointestinal Vagal Afferents Following Neurotrauma, Emily N. Blanke, Gregory M. Holmes, Emily M. Besecker
Health Sciences Faculty Publications
The adaptability of the central nervous system has been revealed in several model systems. Of particular interest to central nervous system-injured individuals is the ability for neural components to be modified for regain of function. In both types of neurotrauma, traumatic brain injury and spinal cord injury, the primary parasympathetic control to the gastrointestinal tract, the vagus nerve, remains anatomically intact. However, individuals with traumatic brain injury or spinal cord injury are highly susceptible to gastrointestinal dysfunctions. Such gastrointestinal dysfunctions attribute to higher morbidity and mortality following traumatic brain injury and spinal cord injury. While the vagal efferent output remains …
Sperm Dna Methylation Mediates The Association Of Male Age On Reproductive Outcomes Among Couples Undergoing Infertility Treatment, Oladele A. Oluwayiose, Haotian Wu, Hachem Saddiki, Brian W. Whitcomb, Laura B. Balzer, Nicole Brandon, Alexander Suvorov, Rahil Tayyab, Cynthia K. Sites, Lisa Hill, Chelsea Marcho, J. Richard Pilsner
Sperm Dna Methylation Mediates The Association Of Male Age On Reproductive Outcomes Among Couples Undergoing Infertility Treatment, Oladele A. Oluwayiose, Haotian Wu, Hachem Saddiki, Brian W. Whitcomb, Laura B. Balzer, Nicole Brandon, Alexander Suvorov, Rahil Tayyab, Cynthia K. Sites, Lisa Hill, Chelsea Marcho, J. Richard Pilsner
Environmental Health Sciences Faculty Publication Series
Parental age at time of offspring conception is increasing in developed countries. Advanced male age is associated with decreased reproductive success and increased risk of adverse neurodevelopmental outcomes in offspring. Mechanisms for these male age effects remain unclear, but changes in sperm DNA methylation over time is one potential explanation. We assessed genome-wide methylation of sperm DNA from 47 semen samples collected from male participants of couples seeking infertility treatment. We report that higher male age was associated with lower likelihood of fertilization and live birth, and poor embryo development (p < 0.05). Furthermore, our multivariable linear models showed male age was associated with alterations in sperm methylation at 1698 CpGs and 1146 regions (q < 0.05), which were associated with > 750 genes enriched in embryonic development, behavior and neurodevelopment …
Developmental Exposures To Perfluorooctanesulfonic Acid (Pfos) Impact Embryonic Nutrition, Pancreatic Morphology, And Adiposity In The Zebrafish, Danio Rerio, Karilyn E. Sant, Kate Annunziato, Sarah Conlin, Gregory Teicher, Phoebe Chen, Olivia Venezia, Gerald B. Downes, Yeonhwa Park, Alicia R. Timme-Laragy
Developmental Exposures To Perfluorooctanesulfonic Acid (Pfos) Impact Embryonic Nutrition, Pancreatic Morphology, And Adiposity In The Zebrafish, Danio Rerio, Karilyn E. Sant, Kate Annunziato, Sarah Conlin, Gregory Teicher, Phoebe Chen, Olivia Venezia, Gerald B. Downes, Yeonhwa Park, Alicia R. Timme-Laragy
Environmental Health Sciences Faculty Publication Series
Perfluorooctanesulfonic acid (PFOS) is a persistent environmental contaminant previously found in consumer surfactants and industrial fire-fighting foams. PFOS has been widely implicated in metabolic dysfunction across the lifespan, including diabetes and obesity. However, the contributions of the embryonic environment to metabolic disease remain uncharacterized. This study seeks to identify perturbations in embryonic metabolism, pancreas development, and adiposity due to developmental and subchronic PFOS exposures and their persistence into later larval and juvenile periods. Zebrafish embryos were exposed to 16 or 32 μM PFOS developmentally (1–5 days post fertilization; dpf) or subchronically (1–15 dpf). Embryonic fatty acid and macronutrient concentrations and …
Space-Time Characterization Of Community Noise And Sound Sources In Accra, Ghana, Sierra N. Clark, Abosede S. Alli, Ricky Nathvani, Allison Hughes, Majid Ezzati, Michael Brauer, Mireille B. Toledano, Jill Baumgartner, James E. Bennett, James Nimo
Space-Time Characterization Of Community Noise And Sound Sources In Accra, Ghana, Sierra N. Clark, Abosede S. Alli, Ricky Nathvani, Allison Hughes, Majid Ezzati, Michael Brauer, Mireille B. Toledano, Jill Baumgartner, James E. Bennett, James Nimo
Environmental Health Sciences Faculty Publication Series
Urban noise pollution is an emerging public health concern in growing cities in sub-Saharan Africa (SSA), but the sound environment in SSA cities is understudied. We leveraged a large-scale measurement campaign to characterize the spatial and temporal patterns of measured sound levels and sound sources in Accra, Ghana. We measured sound levels and recorded audio clips at 146 representative locations, involving 7-days (136 locations) and 1-year measurements between 2019 and 2020. We calculated metrics of noise levels and intermittency and analyzed audio recordings using a pre-trained neural network to identify sources. Commercial, business, and industrial areas and areas near major …
Three Roles Of Narratives In The Treatment Of Chronic Pain, Nina Atanasova
Three Roles Of Narratives In The Treatment Of Chronic Pain, Nina Atanasova
Philosophy and Religious Studies Department Faculty Publications
In this paper, I discuss the roles narratives play in the diagnostics, treatment, and recovery of chronic pain patients. I show that the successes of this narrative approach to the treatment of chronic pain support the biopsychosocial model of disease. The central example of narrative interventions discussed in the paper is pain neuroscience education. This is an intervention which aims at helping chronic pain patients reconceptualize their pain experiences so as to align them with neuroscientific knowledge of pain. Multiple clinical trials have established the success of these interventions in pain reduction. This shows that neuroscience pain education is in …