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Altered Physiology Of Gastrointestinal Vagal Afferents Following Neurotrauma, Emily N. Blanke, Gregory M. Holmes, Emily M. Besecker
Altered Physiology Of Gastrointestinal Vagal Afferents Following Neurotrauma, Emily N. Blanke, Gregory M. Holmes, Emily M. Besecker
Health Sciences Faculty Publications
The adaptability of the central nervous system has been revealed in several model systems. Of particular interest to central nervous system-injured individuals is the ability for neural components to be modified for regain of function. In both types of neurotrauma, traumatic brain injury and spinal cord injury, the primary parasympathetic control to the gastrointestinal tract, the vagus nerve, remains anatomically intact. However, individuals with traumatic brain injury or spinal cord injury are highly susceptible to gastrointestinal dysfunctions. Such gastrointestinal dysfunctions attribute to higher morbidity and mortality following traumatic brain injury and spinal cord injury. While the vagal efferent output remains …