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Full-Text Articles in Nanotechnology
Development Of New Biological Nanopores And Their Application For Biosensing And Disease Detection, Shaoying Wang
Development Of New Biological Nanopores And Their Application For Biosensing And Disease Detection, Shaoying Wang
Theses and Dissertations--Pharmacy
Nanopore technology has recently emerged as a new real-time single molecule sensing method. The current dominant technologies, such as mass spectrometry and immunoassay, for protein analysis is still slow and complex, which can’t meet the urgent need and fields of use. Development of a highly simple, portable and sensitive detection system for pathogen detection, disease diagnosis, and environmental monitoring is in great need. Membrane embedded Phi29 connector nanopore, the first protein nanopore coming from bacteriophage, was mainly focusing on DNA and RNA translocation in previous studies. Here, Phi29 connector nanopore was first time established for antibody detection by engineering Epithelial …