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Full-Text Articles in Nanotechnology
Synthesis And Characterization Of Cr-Znga2o4 And Eu-Ca3(Po4)2 Composite, Benjamin Hulme
Synthesis And Characterization Of Cr-Znga2o4 And Eu-Ca3(Po4)2 Composite, Benjamin Hulme
Undergraduate Student Research Internships Conference
No abstract provided.
Peptide Conjugation Of Branched Amphiphilic Peptide Capsules, Baltazar Claro-Martinez
Peptide Conjugation Of Branched Amphiphilic Peptide Capsules, Baltazar Claro-Martinez
Kansas State University Undergraduate Research Conference
In recent years, nanocarrier cellular therapy has been a rapidly growing area for research in the treatment of malignant and infectious diseases – most notably cancer. Conventional cancer treatment has consisted of highly toxic, highly insoluble, untargeted delivery of drugs that kill both cancerous and healthy cells. Research in the Tomich lab consists of the synthesis of Branched Amphiphilic Peptide Capsules (BAPCs), which are self-assembling peptide nanospheres composed of one or both of these branched peptide sequences: h5 and h9. These peptides possess similar molecular characteristics of phosphoglycerides but are synthesized chemically within the lab. Previous publications by the Tomich …
Engineering Fret Biosensors For Microrna Presence/Absence Analysis, Nicholas E. Larkey, Sean M. Burrows
Engineering Fret Biosensors For Microrna Presence/Absence Analysis, Nicholas E. Larkey, Sean M. Burrows
Biomedical Engineering Western Regional Conference
No abstract provided.
Nanobubbles Provide Theranostic Relief To Cancer Hypoxia, Christopher M. Long, Pushpak N. Bhandari, Joseph Irudayaraj
Nanobubbles Provide Theranostic Relief To Cancer Hypoxia, Christopher M. Long, Pushpak N. Bhandari, Joseph Irudayaraj
The Summer Undergraduate Research Fellowship (SURF) Symposium
Hypoxia is a common motif among tumors, contributing to metastasis, angiogenesis, cellular epigenetic abnormality, and resistance to cancer therapy. Hypoxia also plays a pivotal role in oncological studies, where it can be used as a principal target for new anti-cancer therapeutic methods. Oxygen nanobubbles were designed in an effort to target the hypoxic tumor regions, thus interrupting the hypoxia-inducible factor-1α (HIF-1α) regulatory pathway and inhibiting tumor progression. At less than 100nm, oxygen nanobubbles act as a vehicle for site-specific oxygen delivery, while also serving as an ultrasound contrast agent for advanced imaging purposes. Through in vitro and in vivo studies, …
Design And Development Of A Plasmid Vector For Protein Expression And Purification, Mahima Grover, Craig Sweet, David H. Thompson
Design And Development Of A Plasmid Vector For Protein Expression And Purification, Mahima Grover, Craig Sweet, David H. Thompson
The Summer Undergraduate Research Fellowship (SURF) Symposium
Production and isolation of proteins are difficult, costly and time-consuming processes. The aim of this project is for the development of plasmids, which allow for streamlined production and isolation of proteins. To allow for modular insertion of varying segments of DNA we are using ‘recursive directional ligation by plasmid reconstruction’. This technique uses type II restriction endonucleases, which cut downstream from their recognition site allowing multiple insertions without losing a restriction site. Using this process, we can ligate multiple DNA sequences together and express them to be able to construct a scar less fusion protein. In order to accomplish this, …