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Full-Text Articles in Other Mental and Social Health

Are Thyrotropin-Releasing Hormone (Trh) And Analog Taltirelin Viable Reversal Agents Of Opioid-Induced Respiratory Depression?, Marieke Hyke Algera, Joseph F Cotten, Monique Van Velzen, Marieke Niesters, Martijn Boon, Daniel S Shoham, Kaye E Dandrea, Rutger Van Der Schrier, Albert Dahan Jun 2022

Are Thyrotropin-Releasing Hormone (Trh) And Analog Taltirelin Viable Reversal Agents Of Opioid-Induced Respiratory Depression?, Marieke Hyke Algera, Joseph F Cotten, Monique Van Velzen, Marieke Niesters, Martijn Boon, Daniel S Shoham, Kaye E Dandrea, Rutger Van Der Schrier, Albert Dahan

Faculty and Staff Publications

Opioid-induced respiratory depression (OIRD) is a potentially life-threatening complication of opioid consumption. Apart from naloxone, an opioid antagonist that has various disadvantages, a possible reversal strategy is treatment of OIRD with the hypothalamic hormone and neuromodulator thyrotropin-releasing hormone (TRH). In this review, we performed a search in electronic databases and retrieved 52 papers on the effect of TRH and TRH-analogs on respiration and their efficacy in the reversal of OIRD in awake and anesthetized mammals, including humans. Animal studies show that TRH and its analog taltirelin stimulate breathing via an effect at the preBötzinger complex, an important respiratory rhythm generator …


The Impact Of Covid-19 On The Opioid Epidemic, Hailey Stewart May 2022

The Impact Of Covid-19 On The Opioid Epidemic, Hailey Stewart

Undergraduate Honors Theses

The COVID-19 pandemic adversely affected the lives of most Americans. People with Substance Use Disorder (SUD) were particularly vulnerable to the negative effects brought on by the pandemic. This study explored the increase in deaths due to opioid overdose during the pandemic exacerbated by factors such as increased stress, decrease in treatment options due to social distancing requirements and facility closures, social isolation, and an increase in spare time. Access to treatment for opioid use disorder (OUD) was interrupted by the measures meant to mitigate the spread of COVID-19. Through a systematic review of current literature, it was demonstrated that …


Pandemic And Substance Use: A Cross-Sectional Analysis, Vanessa E. Ermilio May 2022

Pandemic And Substance Use: A Cross-Sectional Analysis, Vanessa E. Ermilio

Electronic Theses, Projects, and Dissertations

Background: The COVID-19 Pandemic called individuals to stay at home which may have impacted individuals to become not only physically, but socially isolated as well. With social isolation, comes an increase in mental health complications which may lead to an increase in substance use. The purpose of this study was to evaluate the potential association between COVID-19 social isolation and substance use among college students.

Method: The present study’s data was collected from a public, four-year university located in Southern California. The survey was disseminated through instructors at the university and students were incentivized with extra course credit to participate. …


Dnp Final Report: Adolescent Support For Healthy Living, Kristin S. Hudson Apr 2022

Dnp Final Report: Adolescent Support For Healthy Living, Kristin S. Hudson

DNP Final Reports

Adolescents often make decisions that negatively impact their health and wellness. They do this for many reasons including impulsivity, underdeveloped communication and coping skills, feelings of invincibility, and a perceived lack of support. In adolescents, how does education and training related to risky behaviors compared to no education affect knowledge, skills, and understanding (KSU) of high-risk behaviors three months after instruction? Thirteen peer- reviewed articles were utilized in the body of evidence. A curriculum-based intervention was implemented. Outcomes include an overall increase in KSU in six key concepts including contraception, substances abuse, sexually transmitted diseases/infections, teen pregnancy, peer pressure, and …


Integrating Psychedelic Experiences Through Touch, James Salomons Mar 2022

Integrating Psychedelic Experiences Through Touch, James Salomons

Journal of Transformative Touch

No abstract provided.


Implementation Of Mental And Substance Misuse Screenings Into Routine Prep Therapy Encounters, Kieran Talkiewicz Jan 2022

Implementation Of Mental And Substance Misuse Screenings Into Routine Prep Therapy Encounters, Kieran Talkiewicz

Capstone Showcase

It has been well documented over the years that lesbian, gay, bisexual, transgender, queer/ questioning (LGBTQ+) populations are disproportionately affected by a higher burden of mental health illnesses, alcohol abuse, and illicit substance abuse when compared to heterosexual populations. This article will recommend utilizing routine Pre-Exposure Prophylaxis (PrEP) therapy encounters, a common point of contact for primary care for sexual minority populations, to perform screening for mental health and substance use. Due to men who have sex with men (MSM) being the highest utilizing population of this therapy, and disproportionately burdened by psychiatric and substance use disorders, this article will …


Influence Of Social Expectations On Muscle Dysmorphia In College-Age Males Studying Exercise Science, Quinten Garver Jan 2022

Influence Of Social Expectations On Muscle Dysmorphia In College-Age Males Studying Exercise Science, Quinten Garver

Williams Honors College, Honors Research Projects

PURPOSE: To investigate the correlation between the risk of an individual developing MD and the presence of unrealistic social expectations. The research question is “How do unrealistic social expectations influence the development of muscle dysmorphia in college-age males studying exercise science?”. METHODS: An electronic survey was distributed to all exercise science students at The University of Akron. This survey was targeted exclusively at male students; any responses received by females were not analyzed. The survey consisted of 20 questions that were aimed at determining the individual’s risk of developing muscle dysmorphia and determining how likely the individual is to have …


Mindfulness And Pain Regulation: The Role Of Acceptance And Commitment Therapy For Individuals With Chronic Pain, Ariana C. White Jan 2022

Mindfulness And Pain Regulation: The Role Of Acceptance And Commitment Therapy For Individuals With Chronic Pain, Ariana C. White

Honors Theses and Capstones

Chronic pain is a significant and widely prevalent health condition which requires comprehensive care to address the many facets contributing to symptomatology. In 2016, 20% of American adults (about 50 million) reported experiencing chronic pain, of which 7.4% indicated that chronic pain frequently limited their life and participation in activities within the past 3 months (CDC, 2018). As a result, many individuals with chronic pain turn to opioid-based medication for pain relief, but long-term use of opioids actually increases pain sensation (Tobin, 2019). Moreover, opioid medication is unable to target underlying mental health components which emerge as part of chronic …