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Impaired Cardiorespiratory Fitness Following Thoracic Radiotherapy, Justin M. Canada
Impaired Cardiorespiratory Fitness Following Thoracic Radiotherapy, Justin M. Canada
Theses and Dissertations
Cancer (CA) is the second leading cause of death in the United States preceded only by cardiovascular disease (CVD). Over the past 30 years, the 5-year survival rate for all cancers combined has increased by more than 20%. This improved survival rate is due to early diagnosis and advances in treatment involving a multimodality treatment approach that includes radiotherapy [RT] with about half of all CA patients receiving some type of RT sometime during the course of their treatment. Cardiotoxicity is one of the most important adverse reactions of RT and leads to a meaningful risk of CVD-related morbidity and …