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Full-Text Articles in Medical Sciences

Pentylenetetrazol-Induced Seizures In Pigeons And The Effects Of Ethosuximide Thereon, James J. Jakubow Dec 1988

Pentylenetetrazol-Induced Seizures In Pigeons And The Effects Of Ethosuximide Thereon, James J. Jakubow

Masters Theses

Previous research has shown that ethosuximide in high enough doses will disrupt operant responding in pigeons. Whether or not these same doses will protect against seizure activity in this species has not been previously tested.

To test this question a system for scoring pentylenetetrazol-induced seizures in pigeons was developed and the effects of ethosuximide on such seizures were evaluated. In Experiment 1 pentylenetetrazol at 15, 27 and 47 mg/kg reliably induced seizures. In Experiment 2 non-behaviorally active and behaviorally active doses of ethosuximide were tested for their seizure controlling effectiveness.

Doses of 20, 40, 80, 160 and 320 mg/kg ethosuximide …


A Biomechanical Analysis Of The Effect Wear Patterns Of Running Shoes Have On Kinematic Variables Of The Lower Extremities, Audrey E. Randall Apr 1988

A Biomechanical Analysis Of The Effect Wear Patterns Of Running Shoes Have On Kinematic Variables Of The Lower Extremities, Audrey E. Randall

Masters Theses

The purpose of the study was to investigate the relationship between wear patterns of running shoes and selected kinematic variables of the lower extremities. Statistical analyses were completed by using a case study design for two male subjects. Subjects were filmed for ten strides on six different sessions over a three-month period. A two-way ANOVA design, with repeated measures, evaluated the dependent variables: (a) footstrike, (b) midstance and (c) toeoff phases. The degree of change was determined by digitizing ten points on the body. A University of California, Los Angeles, BMDP2V statistical package was used to determine differences between means. …