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Full-Text Articles in Medical Sciences

Fibrinogen Birmingham: A Heterozygous Dysfibrinogenemia (Aα 16 Arg → His) Containing Heterodimeric Molecules, Kevin R. Siebenlist, J. T. Prchal, Michael W. Mosesson Mar 1988

Fibrinogen Birmingham: A Heterozygous Dysfibrinogenemia (Aα 16 Arg → His) Containing Heterodimeric Molecules, Kevin R. Siebenlist, J. T. Prchal, Michael W. Mosesson

Biomedical Sciences Faculty Research and Publications

Fibrinogen was isolated from the plasma of a 25-year-old female with a history of mild bleeding and several recent moderate to severe hemorrhagic episodes. Coagulability with thrombin approached 100% and varied directly with the time of incubation with the enzyme. High- performance liquid chromatography analysis of thrombin-induced fibrinopeptide release demonstrated retarded fibrinopeptide A (FPA) and fibrinopeptide B (FPB) release and the presence of an abnormal A peptide (FPA) amounting to 50% of the total. The same biochemical abnormalities were found in her asymptomatic father. Amino acid analysis and carboxypeptidase digestion of FPA demonstrated the substitution of His for Arg at …


An Anatomical And Physiological Investigation Of Hippocampal Connections Involved In Cardiovascular Control, Kenneth Gary Ruit Jan 1988

An Anatomical And Physiological Investigation Of Hippocampal Connections Involved In Cardiovascular Control, Kenneth Gary Ruit

Dissertations

No abstract provided.


Asymmetrical Sensory And Motor Patterns In Individuals With Inverted And Noninverted Handwriting Postures, James Brian Pope Jan 1988

Asymmetrical Sensory And Motor Patterns In Individuals With Inverted And Noninverted Handwriting Postures, James Brian Pope

Dissertations, Theses, and Masters Projects

No abstract provided.