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Medical Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Virginia Commonwealth University

1987

Articles 1 - 2 of 2

Full-Text Articles in Medical Sciences

Nosocomial Respiratory Tract Infections Associated With The Use Of Ventilatory Support Systems: Epidemiological And Bacteriological Study Of The Effect Of Changing Breathing Circuits At 24 Or 48 Hours, Virginia Archer Lamb Jan 1987

Nosocomial Respiratory Tract Infections Associated With The Use Of Ventilatory Support Systems: Epidemiological And Bacteriological Study Of The Effect Of Changing Breathing Circuits At 24 Or 48 Hours, Virginia Archer Lamb

Theses and Dissertations

Nosocomial (hospital-acquired) pneumonia (HAP) continues to be an important cause of morbidity and mortality in the hospital. HAP is the third most common nosocomial infection after urinary tract and surgical wound infections. In addition, HAP is the nosocomial infection with the highest mortality rate. These infections are often difficult to treat, because most are caused by Gram-negative bacilli (GNB) that may be highly resistant to antimicrobial agents. HAPs frequently occur in intensive care patients with underlying lung and/or systemic diseases. Many patients are intubated and are on assisted ventilation. Several sources of infection associated with ventilators or respirators have been …


Comparison Of Virulent And Avirulent Legionella Pneumophila And Evaluation Of Fish As A Potential Environmental Reservoir/Experimental Model, Sandra Reading Sommer Jan 1987

Comparison Of Virulent And Avirulent Legionella Pneumophila And Evaluation Of Fish As A Potential Environmental Reservoir/Experimental Model, Sandra Reading Sommer

Theses and Dissertations

Legionella pneumophila was first recognized as a cause of human pneumonia in 1976 . Since then, much has been learned about the microbiology, pathophysiology and epidemiology of this organism. The features which permit one strain but not another to invade human lung tissue and produce disease remain incompletely understood. This study e valuated several attributes of a virulent and an avirulent strain of L. pneumophila in an attempt to identify characteristics which would distinguish the two. Evaluation of a new medium, buffered egg yolk agar, showed that virulence was maintained after 26 passages, which was the same as the buffered …