Open Access. Powered by Scholars. Published by Universities.®
Congenital, Hereditary, and Neonatal Diseases and Abnormalities Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Animal Experimentation and Research (1)
- Cardiology (1)
- Cardiovascular Diseases (1)
- Cell and Developmental Biology (1)
- Cellular and Molecular Physiology (1)
-
- Chemicals and Drugs (1)
- Cognitive Neuroscience (1)
- Development Studies (1)
- Developmental Biology (1)
- Developmental Neuroscience (1)
- Medical Sciences (1)
- Neurology (1)
- Neuroscience and Neurobiology (1)
- Neurosciences (1)
- Organic Chemicals (1)
- Other Cell and Developmental Biology (1)
- Other Physiology (1)
- Pediatrics (1)
- Pharmacology (1)
- Pharmacology, Toxicology and Environmental Health (1)
- Physiology (1)
- Research Methods in Life Sciences (1)
- Social and Behavioral Sciences (1)
Articles 1 - 2 of 2
Full-Text Articles in Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Neurodevelopmental Outcomes Of Infantile Hydrocephalus: An Fmri Case Study, Ikhlas Ahmed Hashi
Neurodevelopmental Outcomes Of Infantile Hydrocephalus: An Fmri Case Study, Ikhlas Ahmed Hashi
Electronic Thesis and Dissertation Repository
Ventricle dilatation caused by infantile hydrocephalus may result in extensive damage of the posterior cortex (parietal and occipital lobes). We hypothesize that pathological changes in the development of the posterior cortex can be linked to non-verbal learning disabilities in children with previous infantile hydrocephalus. This case study will investigate the neurodevelopmental outcomes of 3 treated hydrocephalus patients, when compared to a group of healthy control children (n = 12). Within the hydrocephalus group, patients displayed differences in non-verbal test performance as well as parietal brain activation during an fMRI number comparison task. We associated these differences with clinical variables such …
Maternal Nicotine Exposure Induces Congenital Heart Defects In The Offspring Of Mice, Elizabeth Greco
Maternal Nicotine Exposure Induces Congenital Heart Defects In The Offspring Of Mice, Elizabeth Greco
Electronic Thesis and Dissertation Repository
Congenital heart defects are the most prevalent birth defect, and maternal cigarette smoking is a known risk factor. Nicotine replacement therapies are recommended to pregnant women who smoke to aid in smoking cessation, as this alternative is thought to be much safer compared to cigarette smoking. However, these products contain nicotine, and the safety of nicotine on the developing heart is not well known. In this thesis, a mouse model was used to test the hypothesis that maternal nicotine exposure (MNE) during pregnancy leads to congenital heart defects and coronary artery defects in the offspring of mice. MNE resulted in …