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Philadelphia College of Osteopathic Medicine

Children

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Is Rabeprazole A Safe Treatment For Gastroesophageal Reflux Disease In Children Ages 1-16 Years?, Sarah Applegarth Jan 2015

Is Rabeprazole A Safe Treatment For Gastroesophageal Reflux Disease In Children Ages 1-16 Years?, Sarah Applegarth

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of the selective EBM review is to determine whether or not Rabeprazole is a safe treatment for GERD in children less than sixteen years old.

Study Design: Review of three randomized controlled studies. All three studies were published in English between 2007-2013.

Data Sources: Three randomized, un-blinded, controlled studies found using Medline and PubMed

Outcomes Measured: Each trial measured the adverse events that occurred with the use of Rabeprazole for the treatment of GERD in children less than sixteen years of age. This was done by using subjective reporting of treatment-emergent adverse events (TEAE’s). Differences in the …