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Full-Text Articles in Diseases
Metastatic Breast Cancer Presenting As Painless Jaundice, Daniel S. Wilen Do, Donald J. Mcmahon Do, Brian J. Blair Do, Joanne Kaiser-Smith Do, Darshan B. Roy Md
Metastatic Breast Cancer Presenting As Painless Jaundice, Daniel S. Wilen Do, Donald J. Mcmahon Do, Brian J. Blair Do, Joanne Kaiser-Smith Do, Darshan B. Roy Md
Rowan-Virtua Research Day
Breast cancer is the most commonly diagnosed cancer in women in the United States. Treatment options are wide-‐ ranging based on a multitude of factors, including extent of disease and receptor positivity. Following treatment, a relapse-‐free interval ≥ 2 years carries a more favorable prognosis.
We present a case involving a female with history of breast cancer and relapse-free interval of 15 years who unfortunately presented with metastatic disease involving the liver, bone, and lymph nodes.
Development Of Novel Dual Inhibitor Of Chemokine Receptor 4 And Mcl-1 Against Multiple Myeloma, Kuntal Bhowmick, Kristy K. Patel, Suman Pathi, Subash Jonnalagadda, Tulin Budak-Alpdogan, Manoj K. Pandey
Development Of Novel Dual Inhibitor Of Chemokine Receptor 4 And Mcl-1 Against Multiple Myeloma, Kuntal Bhowmick, Kristy K. Patel, Suman Pathi, Subash Jonnalagadda, Tulin Budak-Alpdogan, Manoj K. Pandey
Rowan-Virtua Research Day
Multiple myeloma (MM) is a neoplastic plasma-cell disorder. This is characterized by clonal proliferation of malignant plasma cells in the bone-marrow (BM) microenvironment, monoclonal protein in blood or urine, and associated organ dysfunction. The treatment options approved by FDA are immune-modulatory agents, proteasome inhibitors, and autologous stem cell transplantation (ASCT). Unfortunately, MM remains uniformly fatal owing to intrinsic or acquired drug resistance and the median survival time is 3 to 5 years. Thus, there is a great need for novel strategies to combat MM.
The intimate relationship of myeloma cells to BM microenvironment is “hallmark of myeloma”. The homing of …
A Rare But Life Threatening Case Of Labile Blood Pressures In Pregnancy, Kelsey Carrio Md, Aarti Aggarwal Md, Susan Mcgroarty Phd
A Rare But Life Threatening Case Of Labile Blood Pressures In Pregnancy, Kelsey Carrio Md, Aarti Aggarwal Md, Susan Mcgroarty Phd
Rowan-Virtua Research Day
Pheochromocytoma is a rare but life threatening adrenal secreting tumor. The infrequency with which it is encountered makes pheochromocytoma, especially in pregnancy, a formidable diagnostic challenge.
Although a pheochromocytoma is rare, it is good to keep it in differential diagnosis as a possible cause of labile BP with headaches and significant orthostatic BP. It is critical to recognize this condition to institute an appropriate therapy & surgical intervention to prevent mortality.