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Full-Text Articles in Diseases
Prevention Of Obesity-Related Morbidity & Mortality In Adults, Rachelle Virgin
Prevention Of Obesity-Related Morbidity & Mortality In Adults, Rachelle Virgin
Masters Theses/Capstone Projects
Poster presentation on the prevention of obesity related morbidity and mortality in adults.
Methotrexate And Cardiovascular Events, Alpesh Shah
Methotrexate And Cardiovascular Events, Alpesh Shah
Electronic Thesis and Dissertation Repository
We conducted a systematic review and meta-analysis to assess the association of MTX with cardiovascular morbidity, cardiovascular mortality and all-cause mortality in patients with autoimmune disease. Our primary outcome was incident cardiovascular events. After screening 13,479 citations, we identified a total of 30 eligible studies. We synthesized adjusted risk estimates using a random effects model. MTX was significantly associated with a 25% reduction in cardiovascular events (pooled RR: 0.75, 95% CI: 0.65, 0.86, I2: 11%), a 55% reduction in cardiovascular mortality (0.45, 95% CI: 0.26, 0.80, I2: 33%) and a 40% reduction in all-cause mortality (0.60, …