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Full-Text Articles in Dentistry
Knowledge, Attitudes, Behavior, And Expectation Of Thai Patients Toward Dental Treatment During Covid-19 Pandemic: An Online Survey, Paratcha Pingsuthiwong
Knowledge, Attitudes, Behavior, And Expectation Of Thai Patients Toward Dental Treatment During Covid-19 Pandemic: An Online Survey, Paratcha Pingsuthiwong
Chulalongkorn University Theses and Dissertations (Chula ETD)
Aerosol-generating procedures with contaminated saliva may pose a risk of disease transmission during the COVID-19 pandemic. COVID-19 preventive measures in dental clinics have evolved in response to the pandemic situation. This research investigated the effect of this pandemic on Thai patients' knowledge, attitudes, and behavior toward dental treatment. The online survey was distributed in June 2022. There were 978 participants in the study. The results showed that most participants had accurate knowledge about the COVID-19 transmission route in dentistry. The mean and median level of concern in the following issues were: contracting COVID-19 in daily life (3.06 and 3.03), contracting …
Association Among Anterior Maxillary Dental Arch Form, Alveolar Bone Thickness And Sagittal Root Position Of Maxillary Central Incisor : A Cone Beam Computed Tomography Analysis, Suttikiat Somvasoontra
Association Among Anterior Maxillary Dental Arch Form, Alveolar Bone Thickness And Sagittal Root Position Of Maxillary Central Incisor : A Cone Beam Computed Tomography Analysis, Suttikiat Somvasoontra
Chulalongkorn University Theses and Dissertations (Chula ETD)
Purpose: This study evaluated the association among the dental arch form, age-sex groups, and sagittal root position regarding alveolar bone thickness in the maxillary central incisor using cone-beam computed tomography (CBCT) images. Materials and Methods: CBCT images of 280 patients were categorized based on the dental arch form and age-sex groups. Five hundred and sixty sagittal CBCT images of the maxillary central incisors were examined to measure the labial and palatal bone thickness at the root apex level, at the mid-root level and 3 mm apically from cemento-enamel junction, with SRP classification. Chi-square, Kruskal-Wallis test, and multiple linear regression were …
Oral Health Service Of Older Adults In Long-Term Care Facilities, Puntawee Barameepipat
Oral Health Service Of Older Adults In Long-Term Care Facilities, Puntawee Barameepipat
Chulalongkorn University Theses and Dissertations (Chula ETD)
To assess oral health service in long-term care facilities in Bangkok Methods: A cross-sectional study was conducted in 50 licensed long-term care facilities in Bangkok. Informed consent was obtained from all participants before conducting phone interviews and administering the questionnaire. The questionnaire covered various aspects, including demographics, health services, and oral health services provided within the long-term care facilities. Results: The study revealed variations in terms of operational years, service capacity, service expense per month, and provision of health services, including oral health services. It was found that the differences in service expenses impacted the provision of denture care for …
Factors Associated With Oral Health Status Among The Healthy Elderly In Phon Thong District, Roi Et Province, Thailand, Yaowapa Chantaraboot
Factors Associated With Oral Health Status Among The Healthy Elderly In Phon Thong District, Roi Et Province, Thailand, Yaowapa Chantaraboot
Chulalongkorn University Theses and Dissertations (Chula ETD)
Objective: This study aimed to identify factors related to the oral health status of healthy elderly people in Phon Thong District, Roi Et Province, Thailand. Materials and methods: This cross-sectional study was conducted between 1 May and 25 December 2020 in Phon Thong District, Roi Et Province. A total of 249 male and female elderly people participated in the study. Oral health information was collected by trained dental hygienists using the Thai version of the oral health assessment tool [OHAT]. Data analysis used Mann–Whitney U tests, Chi-Square tests, and Binary logistic regression. Results: There were statistically significant associations between oral …
Effect Of Normal Saline In Different Concentration On Soft Tissue Healing Of Extraction Wound: A Clinical Study, Walailuk Kunthikarn
Effect Of Normal Saline In Different Concentration On Soft Tissue Healing Of Extraction Wound: A Clinical Study, Walailuk Kunthikarn
Chulalongkorn University Theses and Dissertations (Chula ETD)
Sodium chloride solution (NaCl) is regarded as the most suitable and recommended medical irrigation, because of the nontoxic and isotonic properties. The previous in vitro study showed that NaCl solution induced migration and extracellular matrix excretion from human gingival fibroblast. However, there is no report concerning the effect of rinsing extraction wound with NaCl solution in clinical trial study. This research study is split mouth single-blind randomized controlled clinical trial to investigate if rinsing with 0.9% and 1.8% NaCl solution on extraction wound can promote soft tissue healing. The operation was performed in 60 socket sites. The patients, who had …
Expression Of Superoxide Dismutase 3 (Sod3) During Orthodontic Tooth Movement In Rats, Phanchanit Jindarojanakul
Expression Of Superoxide Dismutase 3 (Sod3) During Orthodontic Tooth Movement In Rats, Phanchanit Jindarojanakul
Chulalongkorn University Theses and Dissertations (Chula ETD)
Hypoxia induces reactive oxygen species (ROS) production in periodontal tissues. Superoxide dismutase 3 (SOD3) is an enzyme protecting cells from ROS. This study investigated SOD3 expression and function during rat orthodontic tooth movement (OTM) and in hypoxia-exposed rat PDL cells. OTM of right maxillary first molars were performed in Sprague-Dawley rats for 1 and 14 days (n = 6 per group). SOD3 and HIF-1α expression were evaluated by immunohistochemistry. SOD3 effects on cell viability and proliferation, ROS production, and mRNA expression of Hif-1α, Rankl, and Opg in PDL cells and osteoclast differentiation were investigated under normoxia and hypoxia. SOD3 expression …
Prediction Of Future Caries In Toddlers Via Salivary Microbiome: A 1-Year Longitudinal Study, Ratcha Raksakmanut
Prediction Of Future Caries In Toddlers Via Salivary Microbiome: A 1-Year Longitudinal Study, Ratcha Raksakmanut
Chulalongkorn University Theses and Dissertations (Chula ETD)
Dental caries in children is the most common chronic oral disease that could disturb their quality of life including their development. Early prevention is a key approach to reducing the prevalence of early childhood caries. However, a reliable caries predictor, as an essential tool for targeted prevention that is important to this approach, is still lacking for infants before caries onset. Therefore, we aimed to develop the caries risk prediction model based on the salivary microbiome of caries-free 1-year-old children to predict caries onset at 1-year follow-up. Using a nested case-control design within a prospective cohort study, 30 saliva samples, …
ความสัมพันธ์ระหว่างสภาวะสุขภาพช่องปากและผลของการฟื้นฟูสมรรถภาพของผู้ป่วยโรคหลอดเลือดสมอง, ปัทมาภรณ์ พุ่มเกาะ
ความสัมพันธ์ระหว่างสภาวะสุขภาพช่องปากและผลของการฟื้นฟูสมรรถภาพของผู้ป่วยโรคหลอดเลือดสมอง, ปัทมาภรณ์ พุ่มเกาะ
Chulalongkorn University Theses and Dissertations (Chula ETD)
วิทยานิพนธ์ฉบับมีวัตถุประสงค์เพื่อศึกษาความสัมพันธ์ระหว่างสภาวะสุขภาพช่องปากและผลของการฟื้นฟูสมรรถภาพของผู้ป่วยโรคหลอดเลือดสมองที่โรงพยาบาลจุฬาลงกรณ์ สภากาชาดไทย มีผู้ป่วยโรคหลอดเลือดสมองระยะฟื้นฟูที่กลับมาติดตามอาการในช่วง 3 เดือน ยินยอมเข้าร่วมโครงการวิจัยทั้งสิ้น 86 ราย ผู้ป่วยโรคหลอดเลือดสมองจะได้รับการตรวจสภาวะสุขภาพช่องปาก ทำการสัมภาษณ์ข้อมูลทั่วไป ร่วมกับการเก็บข้อมูลในเวชระเบียนของผู้ป่วย ใช้สถิติเชิงพรรณนาอธิบายลักษณะของผู้ป่วยโรคหลอดเลือดสมอง และใช้สถิติสหสัมพันธ์แบบเพียร์สันและสเปียร์แมนวิเคราะห์ความสัมพันธ์ระหว่างสภาวะสุขภาพช่องปากกับผลของการฟื้นฟูสมรรถภาพของผู้ป่วยโรคหลอดเลือดสมอง ที่ระดับนัยสำคัญ 0.05 สภาวะสุขภาพช่องปากประเมินจากจำนวนฟันธรรมชาติที่เหลืออยู่ จำนวนคู่สบฟันหลังและคะแนนแบบประเมินสภาวะสุขภาพช่องปากและฟันเทียมฉบับดัดแปลง ผลของการฟื้นฟูสมรรถภาพของผู้ป่วยโรคหลอดเลือดสมองจะประเมินจากการเปลี่ยนแปลงของคะแนนค่าความรุนแรงของโรคหลอดเลือดสมอง ผลการวิจัยพบว่าจำนวนฟันธรรมชาติที่เหลืออยู่และจำนวนคู่สบฟันหลังมีความสัมพันธ์อย่างมีนัยสำคัญทางสถิติกับผลของการฟื้นฟูสมรรถภาพของผู้ป่วยโรคหลอดเลือดสมองพบความสัมพันธ์เป็นแบบสหสัมพันธ์เชิงลบ สรุปผลการวิจัย จำนวนฟันธรรมชาติที่เหลืออยู่และจำนวนคู่สบฟันหลังมีความสัมพันธ์กับผลของการฟื้นฟูสมรรถภาพของผู้ป่วยโรคหลอดเลือดสมองโดยพบความสัมพันธ์มีทิศทางตรงกันข้าม ผู้ป่วยที่มีจำนวนฟันธรรมชาติและจำนวนคู่สบฟันหลังที่มากสัมพันธ์กับค่าความรุนแรงของโรคหลอดเลือดสมองตอนผู้ป่วยออกจากโรงพยาบาลที่มีค่าความรุนแรงน้อยกว่า ผู้ป่วยจึงมีอาการเริ่มต้นไม่รุนแรงส่งผลให้มีการเปลี่ยนแปลงความรุนแรงของโรคน้อยกว่า การดูแลสภาวะสุขภาพช่องปากให้อยู่ในสภาพดีและการเก็บรักษาฟันธรรมชาติสภาพดีไว้ให้ได้มากที่สุดอาจจะเป็นปัจจัยร่วมปัจจัยหนึ่งในการลดความเสี่ยงความรุนแรงของโรคหลอดเลือดสมอง
Influence Of Cad/Cam Materials On Damping Behavior Of Implant-Supported Crown, Charnikan Sukkasam
Influence Of Cad/Cam Materials On Damping Behavior Of Implant-Supported Crown, Charnikan Sukkasam
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study was to investigate the damping capacity of implant-supported crowns made from various computer-aided design and computer-aided manufacturing (CAD-CAM) restorative materials. A titanium implant fixture was embedded in epoxy resin. Crown specimens were divided into three groups: Zirconia (Z), Lithium disilicate (E), and Polymethyl methacrylate (P). Each crown was subdivided into Uncement (Un) and Adhesive resin cement (RC) subgroups (n=5). Specimens were loaded (0-200N). Strain gauges were attached to measure microstrains at crestal and apical levels. Damping capacity was determined based on load-time curves, microstrain-time curves, and time required to reach the maximum load. A two-way ANOVA with Tukey …
ความตรงและความเที่ยงของแบบประเมินผลกระทบของสุขภาพช่องปากสำหรับทีเอ็มดี ฉบับภาษาไทย, รลดา พรธิฤทธิ์
ความตรงและความเที่ยงของแบบประเมินผลกระทบของสุขภาพช่องปากสำหรับทีเอ็มดี ฉบับภาษาไทย, รลดา พรธิฤทธิ์
Chulalongkorn University Theses and Dissertations (Chula ETD)
งานวิจัยนี้มีวัตถุประสงค์เพื่อพัฒนาตัวชี้วัดที่ใช้ประเมินคุณภาพชีวิตในมิติสุขภาพช่องปากชนิด แบบประเมินผลกระทบของสุขภาพช่องปากสำหรับเท็มโพโรแมนดิบิวลาร์ดิสออเดอร์ ฉบับภาษาไทย และทดสอบคุณสมบัติการวัดทางจิตวิทยาของแบบประเมิน วิธีการวิจัยทำโดยการแปลแบบประเมินต้นฉบับภาษาอังกฤษเป็นภาษาไทยและดัดแปลงข้ามวัฒนธรรม รวมถึงทดสอบความตรงเชิงเนื้อหาด้วยการหาค่าดัชนีความเที่ยงตรงของเนื้อหา โดยทันตแพทย์ผู้เชี่ยวชาญด้านทันตกรรมบดเคี้ยวและความเจ็บปวดช่องปากใบหน้าจำนวน 5 ท่าน จากนั้นนำแบบประเมินไปทดสอบกับผู้ป่วยคนไทย แบ่งเป็นกลุ่มผู้ป่วยทีเอ็มดี 110 คน และกลุ่มผู้ป่วยที่ไม่มีภาวะทีเอ็มดีซึ่งเป็นกลุ่มควบคุม 110 คน การทดสอบความเที่ยงภายในใช้การคำนวณค่าสัมประสิทธิ์ครอนบาคแอลฟาจากคะแนน OHIP-TMDs ของกลุ่มผู้ป่วยทีเอ็มดี ทดสอบความตรงเชิงโครงสร้างด้วยวิธีการตรวจสอบจากกลุ่มที่แตกต่างกัน โดยประเมินความแตกต่างของคะแนนของ OHIP-TMDs ระหว่างผู้ป่วยทีเอ็มดีและกลุ่มควบคุม รวมถึงทดสอบความเที่ยงจากการทดสอบซ้ำโดยผู้ป่วยทีเอ็มดี 30 คน กำหนดระยะเวลาห่างกัน 2 วัน และใช้ค่าสัมประสิทธิ์สหสัมพันธ์ภายในชั้นในการคำนวณ การทดสอบทั้งหมดจะกำหนดการทดสอบทางสถิติที่ระดับความเชื่อมั่นร้อยละ 95 ผลการวิจัยพบว่าแบบประเมินผลกระทบของสุขภาพช่องปากสำหรับเท็มโพโรแมนดิบิวลาร์ดิสออเดอร์ ฉบับภาษาไทยที่ถูกพัฒนาขึ้นมีคุณสมบัติการวัดทางจิตวิทยาที่ดี โดยแบบประเมินมีความตรงและความเที่ยงเมื่อนำมาศึกษาในผู้ป่วยคนไทย ซึ่งคะแนนของ OHIP-TMDs ระหว่างกลุ่มผู้ป่วยทีเอ็มดีและกลุ่มควบคุมแตกต่างกันอย่างมีนัยสำคัญทางสถิติ แสดงถึงความตรงเชิงโครงสร้าง รวมถึงมีค่าดัชนีความเที่ยงตรงของเนื้อหาที่ระดับ 0.92 ค่าสัมประสิทธิ์ครอนบาคแอลฟาที่ระดับ 0.942 และค่าสัมประสิทธิ์สหสัมพันธ์ภายในชั้นที่ระดับ 0.808 ดังนั้นแบบประเมิน OHIP-TMDs จึงมีแนวโน้มที่จะนำไปใช้ทางคลินิกสำหรับการประเมินและการจัดการภาวะทีเอ็มดีในกลุ่มผู้ป่วยคนไทยได้
Development Of Patient-Centered Care Scales Of Dentists In Primary Health Care Of Thailand: A Multigroup Analysis, Yutthana Khamnil
Development Of Patient-Centered Care Scales Of Dentists In Primary Health Care Of Thailand: A Multigroup Analysis, Yutthana Khamnil
Chulalongkorn University Theses and Dissertations (Chula ETD)
Purposes: 1. to develop a conceptual construct of patient-centered dental care for primary care dentists in Thailand. 2. to create reliable and valid instruments to measure patient-centered care from both the patient's and dentist's perspectives. 3. to test the measurement invariance of the two scales 4. To examine the effect of personal attributes of patients and dentists on the level of patient-centered care. Materials and Methods: In Phase 1, preliminary questionnaires were developed through a comprehensive process involving a literature review, in-depth interviews, content validity tests, cognitive interviews, and pre-tests. Exploratory factor analysis (EFA) was used to identify the constructs. …
Comparison Of Volumetric Changes At Implant Connector Among Three Different Types Of Abutment After Cyclic Loading, Piyawan Jirayusakamol
Comparison Of Volumetric Changes At Implant Connector Among Three Different Types Of Abutment After Cyclic Loading, Piyawan Jirayusakamol
Chulalongkorn University Theses and Dissertations (Chula ETD)
The aim of this study was to compare the volumetric change of dental implant among three different types of abutments after cyclic loading.Thirty dental implants (4.1x10 mm., Straumann®) were used .All of them were inserted in acrylic resin block with usual surgical protocol to gain primary stability and be able to retrieve for volumetric measurement later. Ten of each dental implant connected with Titanium abutment (Group1: Variobase abutment Straumann®), Gold abutment (Group2: UCLA abutment Straumann®) and Zirconia abutment (Group 3: Care abutment Straumann®) consecutively. Then all specimen was submitted to cyclic loading (1x106 cycles, axial load, 100N, 15 Hz) at …
The Effects Of Decellularized Extracellular Matrix Derived From Jagged1-Treated Human Dental Pulp Stem Cells On Biological Responses Of Stem Cells Isolated From Apical Papilla, Suphalak Phothichailert
The Effects Of Decellularized Extracellular Matrix Derived From Jagged1-Treated Human Dental Pulp Stem Cells On Biological Responses Of Stem Cells Isolated From Apical Papilla, Suphalak Phothichailert
Chulalongkorn University Theses and Dissertations (Chula ETD)
Objective: Indirect Jagged1 immobilization efficiently activates canonical Notch signaling in hDPSCs. This study aimed to investigate the characteristic of the Jagged1-treated hDPSCs-derived dECM and its biological activity on odonto/osteogenic differentiation SCAPs. Methods: Bioinformatic database of Jagged1-treated hDPSCs was analyzed by NetworkAnalyst. hDPSCs seeded on Jagged1 immobilized surface were maintained with N or OM followed by decellularization procedure, dECM-N or dECM-OM, respectively. SCAPs were reseeded on each dECM with either normal medium or OM. Cell viability was determined by MTT assay. Characteristics of dECMs and SCAPs were evaluated by SEM, EDX, immunofluorescent staining and alcian blue staining. A Multipotential differentiation assay. …
Study Of Saliva Transcriptome And Proteome In Thai Patients With Dental Fluorosis, Patcharaporn Gavila
Study Of Saliva Transcriptome And Proteome In Thai Patients With Dental Fluorosis, Patcharaporn Gavila
Chulalongkorn University Theses and Dissertations (Chula ETD)
The purpose of this study was to examine the expression profiles of RNA and protein in Thai individuals with dental fluorosis and compare them with those without fluorosis. Additionally, the study aimed to establish a correlation between the severity of dental fluorosis, urinary fluoride levels, and water fluoride levels. Methods: Schoolchildren in areas endemic for fluoride in Lamphun and Ratchaburi provinces of Thailand were screened for dental fluorosis severity and then enrolled in the study. Fluoride concentration in 24-hour urine and drinking water samples was measured using an ion-selective fluoride electrode. Saliva samples were collected in sterile tubes and stored …
Intention To Obtain Silver Diamine Fluoride Treatment For Dental Caries Among Elderly, Ratchawipa Nakphu
Intention To Obtain Silver Diamine Fluoride Treatment For Dental Caries Among Elderly, Ratchawipa Nakphu
Chulalongkorn University Theses and Dissertations (Chula ETD)
Aims: To evaluate the intention of the elders to use the Silver Diamine Fluoride (SDF) treatment for stopping dental caries progression after being informed Materials and Methods: The elders aged 60-90 years old who are independent and can read Thai were recruited. A questionnaire-guided interview was performed to the elders after introduction of the SDF treatment. The questionnaire-guided interview was guided by the Theory of Reason Action (TRA) composed of 23 questions of 7 constructs including behavioral belief, evaluation of behavioral outcome, normative belief, motivation to comply, attitude towards behavior, subjective norm and intention. The intention to do the SDf …
Cranio-Oro-Facial Features And Masticatory Function In Patients With Craniosynostosis, Yanisa Wongbanthit
Cranio-Oro-Facial Features And Masticatory Function In Patients With Craniosynostosis, Yanisa Wongbanthit
Chulalongkorn University Theses and Dissertations (Chula ETD)
Objectives: The aim of this study was to evaluate cranio-oro-facial features and masticatory function in Thai subjects with craniosynostosis. Methods: Thirteen craniosynostosis (CS) patients aged between 6 - 17 years old who had treatment at the Princess Sirindhorn Craniofacial (PSC) Center, King Chulalongkorn memorial hospital and thirty age-matched non-CS subjects were recruited. Inform consents were obtained. Medical records were retrieved. Craniofacial and oral examination, radiographic evaluation, photograph, and masticatory function were recorded and compared with data of control subjects and that of Thai norms. Results: Among thirteen CS patients, four cases had cleft palate (30.8%), five had anterior openbite (38.5%), …
Awareness Of Medical Doctor On Medication-Related Osteonecrosis Of The Jaw In Osteoporosis Patients, Nachapol Supanumpar
Awareness Of Medical Doctor On Medication-Related Osteonecrosis Of The Jaw In Osteoporosis Patients, Nachapol Supanumpar
Chulalongkorn University Theses and Dissertations (Chula ETD)
Antiresorptive drugs are widely used to treat osteoporosis. A serious adverse effect of these drugs is medication-related osteonecrosis of the jaw (MRONJ). By informing and educating patients about MRONJ, providing proper dental referral, and monitoring the oral health of patients who receive antiresorptive agents, physicians can reduce the risk of MRONJ. We investigated the awareness and clinical practices of physicians in Thailand with regard to MRONJ. Physicians who prescribed antiresorptive drugs for osteoporosis filled out an online self-administered questionnaire about demographic characteristics, awareness, and practices related to MRONJ. Most respondents agreed that antiresorptive drugs may cause MRONJ (92.3%), that poor …
Effects Of The Orthodontic Miniscrew Geometric Design On The Bone Microdamage And Primary Stability, Panida Methawit
Effects Of The Orthodontic Miniscrew Geometric Design On The Bone Microdamage And Primary Stability, Panida Methawit
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study investigated the effects of the pitch (P) and thread shape on orthodontic miniscrew cortical bone microdamage. The relationship between microdamage and primary stability was examined. Ti6Al4V orthodontic miniscrews had custom-made thread heights (H) and pitch sizes and were classified into the following groups: HCPC (control); HCPN (with a narrower pitch); and HTPC (with a taller thread height) (HC = 0.12 mm; HT = 0.36 mm; PC = 0.60 mm; PN = 0.30 mm). The orthodontic miniscrews were inserted in the pilot hole of prepared 1.0-mm-thick tibia cortical bone, and the maximum insertion torque (MIT) and Periotest value (PTV) …
The Effect Of Nano-Silver Fluoride In Remineralization On Artificial Dentine Caries: An In Vitro Study, Peeraya Punpeng
The Effect Of Nano-Silver Fluoride In Remineralization On Artificial Dentine Caries: An In Vitro Study, Peeraya Punpeng
Chulalongkorn University Theses and Dissertations (Chula ETD)
The aim of this in vitro study was to compare the remineralization efficiency among Nano-silver fluoride 400 ppm (NSF400), 38% Silver diamine fluoride (38% SDF) and 5% Sodium fluoride (5% NaF) on artificial dentine caries in permanent molar or premolar teeth. The teeth were sectioned to obtain 120 specimens (3 x 3 x 2 mm3). After artificial caries were created, the lesion depth (LD) was measured using Micro-computed tomography (Micro-CT) (n=15 specimens/group), and the surface microhardness (SMH) was measured using a Knoop microhardness tester (n=15 specimens/group). Subsequently, all specimens were randomly assigned to four groups: Group 1) NSF400, Group 2) …
Evaluation Of Different Scaffolds For Bone Regeneration In Rat Calvarial Bone Defects, Jeerawit Sirakittiworapong
Evaluation Of Different Scaffolds For Bone Regeneration In Rat Calvarial Bone Defects, Jeerawit Sirakittiworapong
Chulalongkorn University Theses and Dissertations (Chula ETD)
Scaffold plays a key role in the context of tissue engineering. It not only provides a structural support for cells, but also creates an appropriate milieu for recruited cells, enhancing the therapeutic effects of cell-based treatments, and enabling the controlled release of biological cues such as growth factors. Collagen is widely used scaffold material in tissue engineering, particularly in periodontal and bone regeneration. Other natural polymers, however, have been developed and can be useful. Therefore, in this study, we aim to investigate the ability of four different natural polymers including collagen, chitosan, silk fibroin, and silk fibroin/gelatin hydrogel in promoting …
Protein Expression After Gingival Injection Of Messenger Rna Encoding Platelet-Derived Growth Factor-Bb In Ligature-Induced Rat Periodontitis, Pimphorn Meekhantong
Protein Expression After Gingival Injection Of Messenger Rna Encoding Platelet-Derived Growth Factor-Bb In Ligature-Induced Rat Periodontitis, Pimphorn Meekhantong
Chulalongkorn University Theses and Dissertations (Chula ETD)
As a new class of medicines, mRNA platform has proven to be safe and effective. The objective of this study was to investigate the effect of local inflammation on platelet derived growth factor-BB (PDGF-BB) expression after gingival injection of PDGF-BB mRNA in lipid nanoparticles (LNPs) in ligature-induced rat periodontitis and to examine the dose-dependent effect of gingival delivery of mRNA. 3-0 silk was placed around maxillary left second molar for two weeks and removed, while the corresponding molar on the right was non-ligated. Under stereomicroscope, a significant bone loss at ligature sites was observed as compared to the non-ligature sites, …
Comparison Of Compressive Strength Between Two Mini Implants :An In Vitro Study, Anchisa Weerasubpong
Comparison Of Compressive Strength Between Two Mini Implants :An In Vitro Study, Anchisa Weerasubpong
Chulalongkorn University Theses and Dissertations (Chula ETD)
Objective: To observe and evaluate the difference in static and dynamic loadings between two mini-implant systems (RetenDent and MS denture® system, OSSTEM). Materials and Methods: Fifty mini-implant from two companies were included in the study. The compressive force was applied to the mini-implants at 30 degrees from its vertical axis. Ten specimens from each group were subjected to static load tests. Subsequently, five cyclic loadings were calculated from static compressive strength. These loads include 320N, 275N, 230N, 185N, and 140N. Three specimens from each group were randomly selected and tested at each loading condition. The Independent T- test was utilized …
The Novel Cyanoacrylate Based Fluoride Varnish, Narongrit Larpbunphol
The Novel Cyanoacrylate Based Fluoride Varnish, Narongrit Larpbunphol
Chulalongkorn University Theses and Dissertations (Chula ETD)
The important factors contributing to the effectiveness of fluoride varnish are the amount of fluoride ion release and the retention time of the varnish on the tooth surface. Commercial fluoride varnishes are susceptible to mechanical removal; therefore, patients are informed to avoid eating for a few hours and refrain from tooth brushing for 12–24 h, which results in patient inconvenience. However, the novel cyanoacrylate based fluoride varnish would not have these disadvantages. This study compared the daily fluoride ion release, abrasion resistance to brushing, and toxicity to human gingival fibroblasts (hGFs) between a newly-developed cyanoacrylate based fluoride varnish and Duraphat …