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Articles 1 - 8 of 8
Full-Text Articles in Dentistry
A Polymerase Chain Reaction Method For The Detection Of Selenomonas Noxia, Arthuro Mehretu
A Polymerase Chain Reaction Method For The Detection Of Selenomonas Noxia, Arthuro Mehretu
UNLV Theses, Dissertations, Professional Papers, and Capstones
In recent studies, periodontal health has been linked to being overweight and/or obese. Among common oral bacteria, Selenomonas noxia has been implicated in converting periodontal health to disease. Selenomonas spp. have also been found in gastric ulcers, and were misdiagnosed as Helicobacter -like organisms, but no further studies were conducted. The increasing clinical and epidemiological importance of S. noxia necessitates the development of a rapid detection method. In this study, a TaqMan 16S rRNA based real-time Polymerase Chain Reaction (PCR) method was developed, optimized and evaluated for the rapid and specific detection of S. noxia . The 16S PCR assay …
Retrospective Evaluation Of Microbial Presence In Existing Saliva Repository: A Pcr Based Molecular Survey Of Oral Microbial Populations From Existing Saliva Samples, Jay Ericksen Davis
Retrospective Evaluation Of Microbial Presence In Existing Saliva Repository: A Pcr Based Molecular Survey Of Oral Microbial Populations From Existing Saliva Samples, Jay Ericksen Davis
UNLV Theses, Dissertations, Professional Papers, and Capstones
The overall purpose of this research project is to explore the link between oral health and disease in the University of Nevada, Las Vegas - School of Dental Medicine (UNLV-SDM) clinic patient population. More specifically, the population of interest is the UNLV-SDM orthodontic clinic patient population, which is mostly composed of adults, females, and minorities. The University of Nevada, Las Vegas, School of Dental Medicine, with more than 70,000 active patients and a post-graduate specialty program in Orthodontics is uniquely positioned to perform this type of oral health epidemiology survey, as well as targeted oral microbial testing among populations within …
Presence Of Porphyromonas Gingivalis In Gingival Squamous Cell Carcinoma, J. Katz, M. Onate, Kaleb M. Pauley, I Bhattacharyya, S. Cha
Presence Of Porphyromonas Gingivalis In Gingival Squamous Cell Carcinoma, J. Katz, M. Onate, Kaleb M. Pauley, I Bhattacharyya, S. Cha
Science and Mathematics Faculty Publications
Periodontal disease has been recently linked to a variety of systemic conditions such as diabetes, cardiovascular disease, preterm delivery, and oral cancer. The most common bacteria associated with periodontal disease, Porphyromonas gingivalis (P. gingivalis) has not yet been studied in the malignant gingival tissues. The objective of this study was to investigate the presence of P. gingivalis in specimens from squamous cell carcinoma patients. We have performed immunohistochemical staining to investigate the presence of P. gingivalis and Streptococcus gordonii (S. gordonii), a non invasive oral bacteria, in paraffin embedded samples of gingival squamous cell carcinoma (n=10) and …
Crosstalk Between Wnt And Rho Pathways In Ameloblast-Lineage Cells, Kate Shusterman
Crosstalk Between Wnt And Rho Pathways In Ameloblast-Lineage Cells, Kate Shusterman
PCOM Biomedical Studies Student Scholarship
Exposure to high levels of fluoride during tooth development will lead to mineralization defects and a decrease in enamel strength, known as enamel fluorosis. It has been proposed that fluoride may alter the cytoskeleton of ameloblasts, cells that secrete enamel during tooth development. This change is carried out through the Rho pathway, more specifically through RhoA. RhoA is stimulated by Wnt3a, a part of the Wnt pathway involved in regulation of cell proliferation and differentiation. The main component of the Wnt pathway, β-catenin, is expressed in dental epithelium and acts by linking cadherins to the actin cytoskeleton in cell adhesion. …
13th Annual Pacific Research Day Abstracts, University Of The Pacific
13th Annual Pacific Research Day Abstracts, University Of The Pacific
Excellence Day
No abstract provided.
Novel Model For Multispecies Biofilms That Uses Rigid Gas-Permeable Lenses, Rebecca Peyyala, Sreenatha S. Kirakodu, Jeffrey L. Ebersole, Karen F. Novak
Novel Model For Multispecies Biofilms That Uses Rigid Gas-Permeable Lenses, Rebecca Peyyala, Sreenatha S. Kirakodu, Jeffrey L. Ebersole, Karen F. Novak
Center for Oral Health Research Faculty Publications
Oral biofilms comprise complex multispecies consortia aided by specific inter- and intraspecies interactions occurring among commensals and pathogenic bacterial species. Oral biofilms are primary initiating factors of periodontal disease, although complex multifactorial biological influences, including host cell responses, contribute to the individual outcome of the disease. To provide a system to study initial stages of interaction between oral biofilms and the host cells that contribute to the disease process, we developed a novel in vitro model system to grow biofilms on rigid gas-permeable contact lenses (RGPLs), which enable oxygen to permeate through the lens material. Bacterial species belonging to early- …
Fracture In Teeth—A Diagnostic For Inferring Bite Force And Tooth Function, Paul J. Constantino, Brian R. Lawn, James J.-W. Lee, Peter W. Lucas
Fracture In Teeth—A Diagnostic For Inferring Bite Force And Tooth Function, Paul J. Constantino, Brian R. Lawn, James J.-W. Lee, Peter W. Lucas
Biological Sciences Faculty Research
Teeth are brittle and highly susceptible to cracking. We propose that observations of such cracking can be used as a diagnostic tool for predicting bite force and inferring tooth function in living and fossil mammals. Laboratory tests on model tooth structures and extracted human teeth in simulated biting identify the principal fracture modes in enamel. Examination of museum specimens reveals the presence of similar fractures in a wide range of vertebrates, suggesting that cracks extended during ingestion or mastication. The use of ‘fracture mechanics’ from materials engineering provides elegant relations for quantifying critical bite forces in terms of characteristic tooth …
Hydrolysis Of Amelogenin By Matrix Metalloprotease-20 Accelerates Mineralization In Vitro, Vuk Uskoković, Feroz Khan, Haichuan Liu, Halina Ewa Witkowska, Li Zhu, Wu Li, Stefan Habelitz
Hydrolysis Of Amelogenin By Matrix Metalloprotease-20 Accelerates Mineralization In Vitro, Vuk Uskoković, Feroz Khan, Haichuan Liu, Halina Ewa Witkowska, Li Zhu, Wu Li, Stefan Habelitz
Pharmacy Faculty Articles and Research
In the following respects, tooth enamel is a unique tissue in the mammalian body: (a) it is the most mineralized and hardest tissue in it comprising up to 95 wt% of apatite; (b) its microstructure is dominated by parallel rods composed of bundles of 40 – 60 nm wide apatite crystals with aspect ratios reaching up to 1:10,000 and (c) not only does the protein matrix that gives rise to enamel guides the crystal growth, but it also conducts its own degradation and removal in parallel. Hence, when mimicking the process of amelogenesis in vitro, crystal growth has to …