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Effects Of Passive Immobilization On Locomotor Recovery After Spinal Cord Injury In Adult Rats., Kelsey Lee Stipp
Effects Of Passive Immobilization On Locomotor Recovery After Spinal Cord Injury In Adult Rats., Kelsey Lee Stipp
Electronic Theses and Dissertations
Background: Spontaneous locomotor recovery in spinal rats has been attributed to animals moving freely in-cage. Environmental enrichment has been shown to increase in-cage movement and functional recovery subsequently. Anxiety has been shown to decrease overnight activity in rats. Methods: Rats were double-housed in medium cages (MC) or single-housed in tiny sized cages (TC). Slotted dividers allowed for partial isolation in TC. Overnight activity was monitored bi-weekly. The open field test and BBB’s were taken weekly. Gait analysis was performed at weeks six and eight. Results: MC showed higher overnight activity and improved gait overtime. No differences were found in BBB …