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Anatomy Commons™

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University of Louisville

Electronic Theses and Dissertations

2014

Articles 1 - 6 of 6

Full-Text Articles in Anatomy

Effects Of Step Training On The Kidneys Following Spinal Cord Injury In Rats., Pradeepa Poudyal Dec 2014

Effects Of Step Training On The Kidneys Following Spinal Cord Injury In Rats., Pradeepa Poudyal

Electronic Theses and Dissertations

Detrusor-sphincter dyssynergia after chronic spinal cord injury (SCI) leads to over-distention, high bladder pressures and vesico-ureteric reflux into the kidney, resulting in repeated infections and pyelonephritis. Given the importance/limited knowledge of SCI effects on the upper urinary tract, this study assessed expression of two proteins in the kidneys of contused (T9) male rats relative to controls that are indicative of tissue stress/damage (TGFβ, CD11b). The impact of two therapeutic rehabilitation strategies, 60 minutes of step training and general exercise, was then assessed on these protein levels relative to non-trained SCI controls, plus the effectiveness of a shorter training duration (30 …

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Boundary Contour Based Surface Representation., Yong Su Dec 2014

Boundary Contour Based Surface Representation., Yong Su

Electronic Theses and Dissertations

We receive most information about our surrounding space and objects through the eyes. To reconstruct the 3D space and objects in the visual system from the 2D retinal images, surface representation must be a critical intermediate stage in the visual processing stream. It is hypothesized in the dissertation that the visual system represents textured surface by a border-to-interior strategy: boundary contours would be encoded first and then border-ownership assignments would be resolved. This process would solve the related problems such as figure-ground segregation, surface depth relationship, occlusion, transparency, etc. As a result, the boundary contours of the surfaces would be …

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Signaling Mechanisms In Regenerative Myogenesis., Sajedah M. Hindi 1986- Dec 2014

Signaling Mechanisms In Regenerative Myogenesis., Sajedah M. Hindi 1986-

Electronic Theses and Dissertations

Skeletal muscle constitutes a highly plastic and malleable tissue that rapidly and profoundly adapts to various environmental and physiological stimuli. This response takes place by means of regulated signaling transduction which elicits changes in gene expression, biochemical, and metabolic properties. Adult muscle is composed by alignment of multinucleated, post mitotic muscle fibers formed during embryonic and neonatal development. Residing in the niche of mature muscle fibers is a small population of undifferentiated muscle progenitors termed satellite cells. Satellite cells are muscle stem cells that carry out regenerative response in adult myofibers. Coordinated signaling emitting from terminally differentiated muscle fibers and …

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Craniodental Anatomy Of A New Late Cretaceous Multituberculate Mammal From Udan Sayr, Mongolia., Amir Subhash Sheth Aug 2014

Craniodental Anatomy Of A New Late Cretaceous Multituberculate Mammal From Udan Sayr, Mongolia., Amir Subhash Sheth

Electronic Theses and Dissertations

Multituberculates were the longest-lived group of early mammals, with a nearly worldwide distribution, and a temporal range from the Middle Jurassic to the Late Eocene. Multituberculates are typically represented by isolated teeth and jaw fragments; however, several localities in Mongolia revealed abundant, well-preserved multituberculate skulls and partial skeletons from the Late Cretaceous. This study is centered on two specimens of a new multituberculate taxon from a locality in the Gobi desert, Udan Sayr. Included is a (1) bone-by-bone description of the cranial and mandibular elements, as well as the dental features of both specimens, PSS-MAE 141 (holotype) and PSS-MAE 142, …

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Effects Of Passive Immobilization On Locomotor Recovery After Spinal Cord Injury In Adult Rats., Kelsey Lee Stipp Aug 2014

Effects Of Passive Immobilization On Locomotor Recovery After Spinal Cord Injury In Adult Rats., Kelsey Lee Stipp

Electronic Theses and Dissertations

Background: Spontaneous locomotor recovery in spinal rats has been attributed to animals moving freely in-cage. Environmental enrichment has been shown to increase in-cage movement and functional recovery subsequently. Anxiety has been shown to decrease overnight activity in rats. Methods: Rats were double-housed in medium cages (MC) or single-housed in tiny sized cages (TC). Slotted dividers allowed for partial isolation in TC. Overnight activity was monitored bi-weekly. The open field test and BBB’s were taken weekly. Gait analysis was performed at weeks six and eight. Results: MC showed higher overnight activity and improved gait overtime. No differences were found in BBB …

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Functional Implications Of Demyelination And The Molecular Control Of Remyelination In The Adult Mouse., Nicholas John Kuypers May 2014

Functional Implications Of Demyelination And The Molecular Control Of Remyelination In The Adult Mouse., Nicholas John Kuypers

Electronic Theses and Dissertations

Oligodendrocyte (OL) loss contributes to the functional deficits underlying diseases with a demyelinating component (Gajjar et al., 1997; Miller et al., 2002). Remyelination can restore these deficits (Duncan et al., 2009). Chapter 1 is an introduction to de- and re-myelination thus providing the necessary background information for consideration in subsequent chapters. Ethidium bromide (EB) has been extensively used in the rat and cat as a model of spinal cord demyelination. However, this lesion has not been addressed in the adult mouse. Therefore, Chapters 2 and 3 characterize a model of chronic EB-induced spinal cord demyelination in the mouse which can …

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