Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 2 of 2

Full-Text Articles in Analytical, Diagnostic and Therapeutic Techniques and Equipment

Validation Of A 5k Age And Weight Run Handicap Model, Paul M. Vanderburgh, Lloyd L. Laubach Mar 2015

Validation Of A 5k Age And Weight Run Handicap Model, Paul M. Vanderburgh, Lloyd L. Laubach

Paul M. Vanderburgh

Though increasing age and body weight (BW) have been widely known to be associated with slower distance run times, the common convention in 5K road races is to categorize competitors by age and, sometimes, BW. This has the disadvantage of assigning only small numbers of competitors to age categories and giving advantage to runners close to the minimum age or BW values allowable. Using recent advances in the modeling of distance run performance by BW combined with empirical evidence quantifying the independent effect of age on cardiovascular endurance, we previously published the derivation of the 5K Handicap (5KH), an age …


Political Drive To Screen For Pre-Dementia: Not Evidence Based And Ignores The Harms Of Diagnosis, David Le Couteur, Jenny A. Doust, Helen Creasey, Carol Brayne Feb 2015

Political Drive To Screen For Pre-Dementia: Not Evidence Based And Ignores The Harms Of Diagnosis, David Le Couteur, Jenny A. Doust, Helen Creasey, Carol Brayne

Jenny Doust

Current policy in many countries is aimed at increasing the rates of diagnosis of dementia and cognitive impairment.1 2 3 This policy drive has been accompanied by research into early detection of dementia, including preclinical identification of underlying neurobiology that might later be associated with dementia.4 Although the clinical features of people with established dementia are unmistakable,5 6 the ability of these preclinical features to predict future disease is less clear. Nevertheless, the belief that there is value in screening for “pre-dementia” or mild cognitive impairment is creeping into clinical practice, with the resulting overdiagnosis having potential adverse consequences for …