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Myocardial Infarction In The Wisconsin Longitudinal Study: The Interaction Among Environmental, Health, Social, Behavioural And Genetic Factors, Tina K. Gonzales, James A. Yonker, Vicky Chang, Carol L. Roan, Pamela Herd, Craig S. Atwood
Myocardial Infarction In The Wisconsin Longitudinal Study: The Interaction Among Environmental, Health, Social, Behavioural And Genetic Factors, Tina K. Gonzales, James A. Yonker, Vicky Chang, Carol L. Roan, Pamela Herd, Craig S. Atwood
Research outputs 2014 to 2021
Objectives:
This study examined how environmental, health, social, behavioural and genetic factors interact to contribute to myocardial infarction (MI) risk.
Design:
Survey data collected by Wisconsin Longitudinal Study (WLS), USA, from 1957 to 2011, including 235 environmental, health, social and behavioural factors, and 77 single- nucleotide polymorphisms were analysed for association with MI. To identify associations with MI we utilized recursive partitioning and random forest prior to logistic regression and chi-squared analyses.
Participants:
6198 WLS participants (2938 men; 3260 women) who (1) had a MI before 72 years and (2) had a MI between 65 and 72 years. …