Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons^™

Development Of A Patient Machine Time Model To Evaluate Dose Perturbation By Respiratory Tumor Motion In Pencil Beam Scanning Proton Radiation Therapy, Mark Artz

Doctoral Dissertations

The pencil beam scanning (PBS) modality for delivering intensity modulated proton radiation therapy is being adopted quickly. Drawing from the dosimetric advantages provided by the Bragg Peak, PBS proton therapy has been shown to produce dose distributions with improved healthy tissue sparing.

Although PBS proton therapy is very promising, lung cancer treatment is not without its challenges. Rapid tissue density changes and respiratory tumor motion present a particularly difficult treatment geometry. The tumor moves continuously within the lung as the patient breathes.

In this project, the dose perturbation of a PBS proton therapy lung plan is evaluated and time based …