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Antimicrobial Resistance And Neisseria Gonorrhoeae Multiantigen Sequence Typing (Ng-Mast) Genotypes In N. Gonorrhoeae During 2012-2014 In Karachi, Pakistan, Kausar Jabeen, Bhawan Mal P, Khan E, Chandio S, Jacobsson S, Unemo M
Antimicrobial Resistance And Neisseria Gonorrhoeae Multiantigen Sequence Typing (Ng-Mast) Genotypes In N. Gonorrhoeae During 2012-2014 In Karachi, Pakistan, Kausar Jabeen, Bhawan Mal P, Khan E, Chandio S, Jacobsson S, Unemo M
Department of Pathology and Laboratory Medicine
Background: Globally, increasing antimicrobial resistance (AMR) in Neisseria gonorrhoea has led to decreased treatment options for gonorrhoea. Continuous monitoring of resistance is crucial to determine evolving resistance trends in Neisseria gonorrhoea and to suggest treatment recommendations. Quality assured gonococcal AMR data from Pakistan are mainly lacking. This study was performed to determine prevalence and trends of gonococcal AMR and molecular epidemiology of local strains during 2012-2014 in Karachi, Pakistan.
Methods: Gonococcal isolates (n = 100) were obtained from urogenital specimens submitted to the Aga Khan University Laboratory, Karachi, Pakistan. Antimicrobial susceptibility was determined using Etest and molecular epidemiology was …