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Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons™
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- Auditory cortex (1)
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- Bariatric surgery (1)
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- FUS (1)
- Focused Ultrasound (1)
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Articles 1 - 6 of 6
Full-Text Articles in Analytical, Diagnostic and Therapeutic Techniques and Equipment
Neuromodulation Of Mouse Auditory Cortex Using Focused Ultrasound, Jacob Hehir
Neuromodulation Of Mouse Auditory Cortex Using Focused Ultrasound, Jacob Hehir
NYMC Student Theses and Dissertations
Neurological diseases impose a large health and financial burden for nations worldwide. Current treatments for many conditions are limited to pharmacological or invasive surgical approaches. Neuromodulation is an alternative therapy wherein electrical currents, magnetic fields, or electromagnetic waves are used to noninvasively modify brain function. Focused ultrasound (FUS) has been shown to alter neural activity, theoretically with much higher spatial resolution than other neuromodulation techniques. However, these predictions assume that neuromodulatory effects are constrained to the acoustic focus. Given that the architecture of neural circuitry in the cerebral cortex supports delicately balanced lateral processing on spatial scales that may exceed …
A Comparative Study Of Three Different Types Of Stem Cells For Treatment Of Rat Spinal Cord Injury, Jiri Ruzicka, L Machova-Urdzikova, John Gillick, T Amemori, N Romanyuk, K Karova, K Zaviskova, J Dubisova, S Kubinova, Raj Murali, E Sykova, Meena Jhanwar-Uniyal, P Jendelova
A Comparative Study Of Three Different Types Of Stem Cells For Treatment Of Rat Spinal Cord Injury, Jiri Ruzicka, L Machova-Urdzikova, John Gillick, T Amemori, N Romanyuk, K Karova, K Zaviskova, J Dubisova, S Kubinova, Raj Murali, E Sykova, Meena Jhanwar-Uniyal, P Jendelova
NYMC Faculty Publications
Three different sources of human stem cells-bone marrow-derived mesenchymal stem cells (BM-MSCs), neural progenitors (NPs) derived from immortalized spinal fetal cell line (SPC-01), and induced pluripotent stem cells (iPSCs)-were compared in the treatment of a balloon-induced spinal cord compression lesion in rats. One week after lesioning, the rats received either BM-MSCs (intrathecally) or NPs (SPC-01 cells or iPSC-NPs, both intraspinally), or saline. The rats were assessed for their locomotor skills (BBB, flat beam test, and rotarod). Morphometric analyses of spared white and gray matter, axonal sprouting, and glial scar formation, as well as qPCR and Luminex assay, were conducted to …
Is It Time To Start Using Mitochondrial Dna Copy Number As An Indicator Of Health And Diseases?, Vasudeva G. Kamath
Is It Time To Start Using Mitochondrial Dna Copy Number As An Indicator Of Health And Diseases?, Vasudeva G. Kamath
Touro College of Osteopathic Medicine (Middletown) Publications and Research
The author discusses whether the medical community should seriously investigate the numerical relation of mitochondrial DNA copy number as a health indicator.
Stability Of Metabolic Factor Before And After Bariatric Surgery, Brandon Davis, Joseph Indelicato
Stability Of Metabolic Factor Before And After Bariatric Surgery, Brandon Davis, Joseph Indelicato
The School of Health Sciences Publications and Research
No abstract provided.
Crispr/Cas9 As A Therapeutic Approach To Duchenne Muscular Dystrophy, Abraham Daniel Levitman
Crispr/Cas9 As A Therapeutic Approach To Duchenne Muscular Dystrophy, Abraham Daniel Levitman
The Science Journal of the Lander College of Arts and Sciences
Transhumanism, designer babies, gene therapy, and super-soldiers are founded upon the same concept—genetic engineering. Clustered Regularly-Interspersed Short Palindromic Repeats (CRISPR) is a natural bacterial immune response method that takes advantage of gene manipulation to prevent an infection from mobile genetic elements. Since Mojica et al. (2005) first suggested the relationship between the CRISPR/Cas system and prokaryotic immunity, significant advancements have been made in understanding the mechanism and subsequent applications of CRISPR. CRISPR, has three main subtypes based on unique proteins and interference pathways and serves as an accurate and effective method for gene editing. Its mechanism consists of spacer acquisition, …
Transposon Based Gene Therapy As A Treatment For Cancer, Jacob Stauber
Transposon Based Gene Therapy As A Treatment For Cancer, Jacob Stauber
The Science Journal of the Lander College of Arts and Sciences
Gene therapy is the use of genes to treat or prevent diseases. Diseases such as cancer, which are difficult to treat using conventional methods, can be treated using gene therapy. The transport of the therapeutic transgene can be accomplished using viral or non-viral methods. However, widespread use of viral vectors is limited due to its high cost of manufacture and safety concern. Non-viral vectors are limited in their effectiveness. The use of transposons such as the Sleeping Beauty transposon system can effectively deliver the transgene with less concern than viral vectors. This review discusses the various vectors and treatment strategies …