Open Access. Powered by Scholars. Published by Universities.®

Diagnosis

University of Rhode Island

Diagnosis

Articles 1 - 1 of 1

Full-Text Articles in Analytical, Diagnostic and Therapeutic Techniques and Equipment

Is Ca-125 The Leading Biomarker In Determining Early-Onset Ovarian Cancer Diagnosis In 2016?, Alexa Clark Apr 2016

Is Ca-125 The Leading Biomarker In Determining Early-Onset Ovarian Cancer Diagnosis In 2016?, Alexa Clark

Senior Honors Projects

Epithelial ovarian cancer is the most lethal gynecologic malignancy with very ineffective efforts at early detection and therapeutic methodologies to reduce mortality. The origin and pathogenicity of ovarian cancer is vastly unclear, which is why diagnosing the disease early on is difficult. CA-125 is a used as therapeutic tumor marker for ovarian cancer, but it is not diagnostic or specific. The role of CA-125 in the early detection of ovarian cancer is extremely controversial and has not been widely accepted for screening in women who do not show any symptoms. In order to enhance the sensitivity for early disease detection …