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Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons™
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Full-Text Articles in Analytical, Diagnostic and Therapeutic Techniques and Equipment
Second Generation Phenyloxadiazolyl Methyl Sulfones For Thiol-Specific Bioconjugations, Guillaume Dewaele-Le Roi
Second Generation Phenyloxadiazolyl Methyl Sulfones For Thiol-Specific Bioconjugations, Guillaume Dewaele-Le Roi
Dissertations, Theses, and Capstone Projects
The role of antibody-based molecular agents for diagnosis and therapy of cancer has expanded significantly over the past decades. However, most of these constructs are synthesized using traditional bioconjugation methods based on the random ligations between the molecular cargo and lysine residues within the protein. These non-specific approaches can create poorly defined conjugates with suboptimal immunoreactivity and in vivo performance while Site-specific approaches to antibody bioconjugation based on ligations between maleimides and free cysteine residues have long stood as attractive alternatives. Yet the inherent instability of the thiol-maleimide linkage has fueled the search for new, more stable thiol-reactive prosthetic groups. …
Design And Development Of A Quartz Crystal Microbalance Immunosensor For Exosomes, Wesley Cox
Design And Development Of A Quartz Crystal Microbalance Immunosensor For Exosomes, Wesley Cox
Chancellor’s Honors Program Projects
No abstract provided.