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Indian Journal of Research in Homoeopathy

Homoeopathic pathogenetic trial

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Full-Text Articles in Alternative and Complementary Medicine

Homoeopathic Drug Proving Researches (1996–2018): A Scoping Review, Raj Manchanda, Anil Khurana, Peter Fisher, Bhopal Arya, Pritha Mehra, Subhranil Saha, Munmun Koley, Meenakshi Bhatia Mar 2020

Homoeopathic Drug Proving Researches (1996–2018): A Scoping Review, Raj Manchanda, Anil Khurana, Peter Fisher, Bhopal Arya, Pritha Mehra, Subhranil Saha, Munmun Koley, Meenakshi Bhatia

Indian Journal of Research in Homoeopathy

Background: A systematic review on homoeopathic pathogenetic trials (HPTs) from 1945 to 1995 was published in 2007, and the basic question whether the effect produced by homoeopathic drugs in healthy human volunteers is equivalent to placebo or otherwise remained unanswered. There is a need to take up another review of HPTs conducted in the last two decades, to assess the changes in the methodologies adapted and to assess whether the effects produced in apparently healthy volunteers is due to homoeopathic medicines in high dilutions or not. Objective: To seek, collect, review and describe HPTs published during 1996–2018. Materials and Methods: …


Homoeopathic Drug Proving Of Mangolia Grandiflora: A Randomised Double Blind Placebo-Controlled Trial, Goutam Rakshit, Vichitra A, Rajpal Singh, Amulya Sahoo, Sujata Choudhury, Vinay Singh Mar 2019

Homoeopathic Drug Proving Of Mangolia Grandiflora: A Randomised Double Blind Placebo-Controlled Trial, Goutam Rakshit, Vichitra A, Rajpal Singh, Amulya Sahoo, Sujata Choudhury, Vinay Singh

Indian Journal of Research in Homoeopathy

Objective: This study was carried out to elicit the pathogenetic response of the drug Magnolia grandiflora in homoeopathic potencies on apparently healthy human beings. Materials and Methods: Drug Magnolia grandiflora was proved by the Central Council for Research in Homoeopathy (CCRH) through a double-blind placebo-controlled method. The study was conducted at three centres. The drug was proved in two potencies (6C and 30C) on 48 apparently healthy volunteers who were selected after conducting pre-trial medical examinations by the medical specialists and routine laboratory investigations. In the first phase, volunteers were given 56 doses (4 doses per day for 14 days) …


Homoeopathic Pathogenetic Trial Of Withania Somnifera: A Multicentric, Double-Blind, Randomised, Placebo-Controlled Trial, Pritha Mehra, Anil Khurana, Renu Mittal, Bhopal Arya, Rajpal Rajpal, Raj Manchanda, Karuna Singh, Anil Vichitra, Goutam Rakshit Jun 2017

Homoeopathic Pathogenetic Trial Of Withania Somnifera: A Multicentric, Double-Blind, Randomised, Placebo-Controlled Trial, Pritha Mehra, Anil Khurana, Renu Mittal, Bhopal Arya, Rajpal Rajpal, Raj Manchanda, Karuna Singh, Anil Vichitra, Goutam Rakshit

Indian Journal of Research in Homoeopathy

Background: Homoeopathic drug proving being the first step in finding the pathogenetic powers of a drug is an integral part of Homoeopathic system of medicine. Objective: To elicit the pathogenetic response of Withania somnifera in homoeopathic potencies on healthy human provers. Materials and Methods: A multicentre, randomised, double-blind, placebo-controlled trial was conducted at four centres under Central Council for Research in Homoeopathy. Proving was conducted on 63 relatively healthy provers. All the provers were given 12 doses of placebo divided into 4 doses/day for 3 days during the first phase of the trial. After randomisation, 43 provers in the intervention …


A Multicentric, Double-Blind Randomized, Homoeopathic Pathogenetic Trial Of Allium Sativum, Raj Manchanda, Anil Khurana, Raj Pal, Bhopal Arya, Anil Vichitra, P Mohanan, Pritha Mehra, Shilpa Sharma Mar 2016

A Multicentric, Double-Blind Randomized, Homoeopathic Pathogenetic Trial Of Allium Sativum, Raj Manchanda, Anil Khurana, Raj Pal, Bhopal Arya, Anil Vichitra, P Mohanan, Pritha Mehra, Shilpa Sharma

Indian Journal of Research in Homoeopathy

Background: Homoeopathic drug proving is an integral part of Homoeopathic System of Medicine. It is the first step in finding out the pathogenetic powers of a drug. Objective: To elicit the pathogenetic response to Allium sativum in homoeopathic potencies on healthy human provers. Materials and Methods: A multi-center randomized, placebo-controlled, double-blind trial was conducted at two centers of the Central Council for Research in Homoeopathy (CCRH). Proving was conducted on 33 healthy provers after the pretrial medical examination. All the provers were given 12 doses of placebo divided in 4 doses/day for 3 days during the first phase of the …


A Double-Blind, Placebo-Controlled Homoeopathic Pathogenetic Trial Of Nanocurcumin 6x, Niranjan Mohanty, Sujata Choudhury, Santosh Jena Sep 2015

A Double-Blind, Placebo-Controlled Homoeopathic Pathogenetic Trial Of Nanocurcumin 6x, Niranjan Mohanty, Sujata Choudhury, Santosh Jena

Indian Journal of Research in Homoeopathy

Background: A double-blind, randomized, placebo-controlled Homoeopathic Pathogenetic Trial (HPT) of Nanocurcumin was conducted using the accepted guidelines, Ethical Committee approval, and scientific documentation. The standardized potentization method was adopted to enhance the quality of the pathogenetic trial. Various statistical calculations were used for evaluation of the symptoms. Aim: The aim of the study was to conduct an HPT of Nanocurcumin 6X, a nano-substance in dilution. Materials and Methods: The drug Nanocurcumin 6X was proved through double-blind, placebo-controlled method. The trial was done in 6X potency on 30 healthy  provers who were screened by their pretrial medical examinations and routine laboratory …


A Multi-Centric Double Blind Homoeopathic Pathogenetic Trial Of Hygrophila Spinosa, G Rakshit, A Vichitra, P Chandra, Rajpal Rajpal, Vinay Singh, S Choudhury Mar 2014

A Multi-Centric Double Blind Homoeopathic Pathogenetic Trial Of Hygrophila Spinosa, G Rakshit, A Vichitra, P Chandra, Rajpal Rajpal, Vinay Singh, S Choudhury

Indian Journal of Research in Homoeopathy

Objective: The study was conducted to elicit the pathogenetic response of Hygrophila spinosa in homoeopathic potencies on healthy human volunteers. Methodology: The drug Hygrophila spinosa was proved by the Central Council for Research in Homoeopathy (CCRH) through randomized, double-blind, placebo-controlled method. The proving was conducted at three centres viz. Central Research Institute (H), [CRI (H)] Noida, Drug Proving Unit [DPU], Bhubaneswar and Regional Research Institute (H) [RRI (H)], Kolkata. The drug was proved in two potencies (6C and 30C) on 48 apparently healthy volunteers who were selected after conducting pre-trial medical examinations by the medical specialists and routine laboratory investigations. …


Proceedings Of Interactive Meet On Harmonisation Of Drug Proving Programme, Raj Manchanda, Anil Khurana, Divya Taneja Mar 2014

Proceedings Of Interactive Meet On Harmonisation Of Drug Proving Programme, Raj Manchanda, Anil Khurana, Divya Taneja

Indian Journal of Research in Homoeopathy

An interactive meet for harmonisation of drug proving programme of the CCRH was held on 17 September 2013 with an objective to exchange information on standards and methods of proving in the USA, Europe and India and promote international collaboration and harmonisation of drug proving protocol. The Council is in the process of revising its drug proving protocol based on the deliberations of the meet.


Hydroquinone: Homoeopathic Pathogenetic Trial, Rajesh Shah Jun 2013

Hydroquinone: Homoeopathic Pathogenetic Trial, Rajesh Shah

Indian Journal of Research in Homoeopathy

Background: A double-blind, randomized, placebo-controlled Homoeopathic Pathogenetic Trial (HPT/Drug Proving) of Hydroquinone was conducted, using the accepted guidelines, ethical approval and scientific documentation The potentization method was standardized. Toward enhancing the quality of HPT, the investigator proposed and evaluated the data using the Quantitative Pathogenetic Index and Qualitative Pathogenetic Index. Usable symptoms were derived from the study. The medicine was suggested for the treatment of vitiligo, based on its known toxicological effects. HPT of a new medicinal substance, using the established parameters, to evaluate symptoms in healthy volunteers was carried out using a controlled experiment. Aims: The aim of the …


A Multi-Centric Double-Blind Randomized Homoeopathic Pathogenetic Trial Of Gymnema Sylvestre, Goutam Rakshit, J Singh, S Pathak, Ch Banoth, P Chandra, Rajpal Rajpal, Sujata Choudhury, Vinay Singh Mar 2013

A Multi-Centric Double-Blind Randomized Homoeopathic Pathogenetic Trial Of Gymnema Sylvestre, Goutam Rakshit, J Singh, S Pathak, Ch Banoth, P Chandra, Rajpal Rajpal, Sujata Choudhury, Vinay Singh

Indian Journal of Research in Homoeopathy

Objective: To elicit the pathogenetic response of Gymnema sylvestre in homoeopathic potencies on apparently healthy human volunteers. Methodology: Gymnema sylvestre was proved by the Central Council for Research in Homoeopathy through double-blind placebo-controlled method. The study was carried out at four centers. The drug was proved in two potencies (6C and 30C) on 63 apparently healthy volunteers who were selected after conducting pre-trial medical examination by the medical specialists and routine laboratory investigations. In the first phase volunteers were given 56 doses (04 doses per day for 14 days) of placebo. In the next two phases 56 doses (04 doses …