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Arcadia University

Agitation

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The Efficacy And Safety Of Tetrahydrocannabinol (Thc) Compared To Traditional Pharmacotherapy In Treating Agitation And Aggression Associated With Dementia, Shane Kalette Jan 2021

The Efficacy And Safety Of Tetrahydrocannabinol (Thc) Compared To Traditional Pharmacotherapy In Treating Agitation And Aggression Associated With Dementia, Shane Kalette

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Introduction: Dementia is a disease that affects the brain and can cause serious deficits in the life of the patient and their family or caregivers.The current mainstay of treatment for agitation and aggression symptoms is atypical antipsychotics, and occasionally off-label SSRIs. Though these methods have shown good efficacy, the number and severity of adverse events that occur with these medications is concerning to patients, families, and providers. Due to the high side-effect profile, many clinicians are looking for an alternative approach with more safety and potentially more efficacy. Among the candidates is tetrahydrocannabinol (THC). This paper investigates the efficacy and …