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A Study Of The Effect Of Mother Tincture Of Syzygium Jambolanum On Metabolic Disorders Of Streptozotocin Induced Diabetic Male Albino Rat, Soumyajit Maiti, Tushar Bera, Kausik Chatterjee, Debidas Ghosh

Indian Journal of Research in Homoeopathy

Background: Syzygium jambolanum is widely used in Homoeopathy for treating Diabetes mellitus and its complications. Objective: To explore the remedial effects of homoeopathic mother tincture Syzygium jambolanum on metabolic disorders of Streptozotocin induced diabetic male albino rat. Materials and Methods: Serum levels of insulin, urea, uric acid, creatinine, albumin and total protein were measured as per the standard methods using specific kits. Amount of glycogen in liver and skeletal muscles, activities of antioxidant enzymes as well as content of free radical bye products in liver and kidney tissues were assessed biochemically following the standard protocol. Results: The study indicated that …

Isolation And Characterization Of Natural Alpha-Glucosidase Inhibitors From Antioxidant Rich Red Wine Grapes (Vitis Vinifera), Hoda Chaouki Kadouh

Wayne State University Dissertations

Background: Diabetes is currently a global public health problem affecting people at all ages. Dietary antioxidants have been associated with a reduced risk of type 2 diabetes. Grape pomace contains considerable amounts of polyphenols and it has been reported to exhibit an inhibitory activity against alpha- glucosidases. Alpha-glucosidases, in turn, play a major role in controlling starch digestion and therefore postprandial blood glucose, a target for diabetes management.

Objective: This study aims to investigate the anti-diabetes potential of a selection of six grape pomaces and prepare and purify active components in the active variety that specifically inhibit intestinal alpha-glucosidases. The …