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Full-Text Articles in Alternative and Complementary Medicine
Honokoil Treatment On Glioblastoma Cells, Julianne Weaver
Honokoil Treatment On Glioblastoma Cells, Julianne Weaver
Honors Theses
Glioblastoma is a malignant brain tumor without effective treatment options available because of its resistance to chemotherapy and radiation. This specific type of cancer is difficult to treat because the cancer stem cells that are not actively growing. These cells are dormant, which means they will not react to treatment because they are not dividing, and it is these cells that result in the high prevalence of relapse. Honokiol is a Chinese magnolia species that is known for its anti-inflammatory, anti-proliferative, and proapoptotic effects which make it an optimal candidate for glioma cell treatment. Honokiol was used in this experiment …
Effectiveness And Mechanism Of Action Of Modified Porphyrins For Photodynamic Therapy Of Triple Negative Breast Cancer Cells, Hannah Brandon
Effectiveness And Mechanism Of Action Of Modified Porphyrins For Photodynamic Therapy Of Triple Negative Breast Cancer Cells, Hannah Brandon
Honors Theses
Triple negative breast cancer (TNBC) is a particularly aggressive form of breast cancer that lacks the three molecules typically targeted for treatment. Standard treatment methods leave much to be desired--the rates of metastasis and recurrence are high and the prognosis for most patients with TNBC is poor. One potential treatment for TNBC is photodynamic therapy (PDT), which uses compounds called photosensitizers that are taken up by all tissues in the body. The tumor is exposed to light, activating the photosensitizer and creating reactive oxygen species that cause cell death. This method is relatively pain-free, effective, and does not harm cells …
Killing Breast Cancer One Porphyrin At A Time, Taylor C. Lymburner
Killing Breast Cancer One Porphyrin At A Time, Taylor C. Lymburner
Honors Theses
New treatments for cancer are continuously being developed and improved. One such treatment is Photodynamic Therapy, more commonly referred to as PDT. PDT is quickly becoming more popular due to its relative lack of side effects that are present in other treatments. In PDT, light-sensitive agents are required and are activated by light in the targeted cells. There are many types of PDT agents but the one focused on in this research is a four-pyrrole ring structure known as a porphyrin. The combination of H2 TPPC with 3- amino-oxetane-3-yl-methanol created the final product ofH2TPP-Oxo-MeOH. Once the porphyrin was formed, it …
An Assessment Of The Effects Of Medical Marijuana On The Quality Of Patient Life, Kori L. Bullard
An Assessment Of The Effects Of Medical Marijuana On The Quality Of Patient Life, Kori L. Bullard
Honors Theses
America is known as the land of opportunity. People attempting to better their lives tend to see America as an opportunity to do so. This statement remains true for the American medical field. Americans are known as advanced in treatment options for various diseases. With this being said, there are few diseases that still bring forth complete fear in the minds of the people of America. In spite of this, "You have been diagnosed with cancer" is a statement that generates this fear. Cancer is one of the leading causes of death worldwide. Current treatments for cancer are invasive, expensive, …
The Effect Of Cannabinoids On Triple Negative Breast Cancer Cells, Haley Dahl
The Effect Of Cannabinoids On Triple Negative Breast Cancer Cells, Haley Dahl
Honors Theses
Triple Negative Breast Cancer (TNBC) is a difficult type of cancer to treat because it is negative for progesterone, estrogen, and HER-2 receptors. Because TNBC is negative for these three receptors, it does not respond to normal hormonal therapies. The purpose of my experiment is to see if different cannabinoids, compounds from the cannabis plants, could be used as alternative treatment options. These experiments employed three different cannabinoids: ajulemic acid, cannabidiol, and hemp oil. Cell viability was measured after 72 hours of treatment using a MTT assay. The results showed that the three cannabinoids could be used to effectively destroy …