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Alternative and Complementary Medicine Commons™
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Full-Text Articles in Alternative and Complementary Medicine
Characterizing The Anxiolytic Potential And Synergistic Efficacy Of Cannabidiol And D-Limonene, Nathashi Jayawardena
Characterizing The Anxiolytic Potential And Synergistic Efficacy Of Cannabidiol And D-Limonene, Nathashi Jayawardena
Electronic Thesis and Dissertation Repository
Emerging evidence has elucidated the anxiolytic properties of the cannabis-derived phytochemicals cannabidiol (CBD) and d-limonene and the ‘Entourage Effect’ wherein, multiple components of cannabis synergize to produce stronger effects than their pure counterparts. However, no studies have yet explored this effect in combinations of CBD and limonene. Thus, the present thesis investigated the anxiolytic and synergistic potential of concurrently administered intra-nucleus accumbens shell CBD (1 ng/0.5 μl or 5 ng/0.5 μl) and inhaled limonene (200 μl or 2000 μl). Additionally, the role of the 5-HT1A receptor in mediating these effects was examined by co-application of the antagonist NAD299 and by …
Investing Into Domestic Manufacturing Of Critical Medication And Vaccines For The Federal Government, Sharon Low
Investing Into Domestic Manufacturing Of Critical Medication And Vaccines For The Federal Government, Sharon Low
All Reports
While the federal government has made numerous public announcements regarding their stimulus plan and promises to increase the domestic capacity to produce personal protective equipment, vaccines, and medical equipment, a critical aspect that has been neglected is the serious and ongoing shortages of critical medication. The government has promised to provide 4.28 billion to expand testing and contact tracing capacities, 7.5 billion towards PPE, and 500 million to the provinces and territories for “critical health care system needs and support for mitigation effects.” While these efforts as part of Trudeau’s Safe Restart Agreement are a good place to begin reducing …