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Exploring The Role Of Cannabidiol-Monoterpene Formulations In Modulating Anxiety Symptoms, Richard Leu

Electronic Thesis and Dissertation Repository

While cannabidiol (CBD) has been documented to elicit anxiolytic effects, only recently have studies been conducted demonstrating the anxiolytic efficacy of the aromatic monoterpene, linalool. Pa

While cannabidiol (CBD) has been documented to elicit anxiolytic effects, only recently have studies demonstrated the anxiolytic efficacy of the aromatic monoterpene, linalool. Past research involving phytocannabinoid-phytocannabinoid formulations has shown that CBD may yield superior anxiolytic efficacy when administered alongside other cannabis compounds, with this phenomenon termed the “Entourage Effect” (EE); however, this EE has not been investigated in phytocannabinoid-terpene formulations. Furthermore, investigations involving intra-cranial CBD administration have shown the nucleus accumbens shell, known …