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Full-Text Articles in Alternative and Complementary Medicine

Ginseng Extract Treatment Influences On Preimplantation Development In Vitro, And Pregnancy And Post-Partum Development In The Mouse, Danyka D. Belanger Jun 2012

Ginseng Extract Treatment Influences On Preimplantation Development In Vitro, And Pregnancy And Post-Partum Development In The Mouse, Danyka D. Belanger

Electronic Thesis and Dissertation Repository

Ginseng is one of the most commonly consumed herbal medicines in the world. Consumption is highest in females, thus my purpose was to define the concentration responsive effects of North American alcoholic and aqueous ginseng extracts on preimplantation development in vitro and on pregnancy and post-partum development in the mouse. 2-cell embryos from female mice were cultured with 5 different concentrations of both extracts, ginsenosides Rb1, Rg1 and Re, a combinatorial ginsenoside solution and a polysaccharide fraction. Embryonic development and recovery from treatment was assessed. To investigate in vivo effects of ginseng extracts, females were gavaged with 50 mg/kg and …


Modulatory Effects Of North American Ginseng Extracts On Human Innate And Adaptive Immune Responses, Holly Rebecca Lemmon Feb 2012

Modulatory Effects Of North American Ginseng Extracts On Human Innate And Adaptive Immune Responses, Holly Rebecca Lemmon

Electronic Thesis and Dissertation Repository

Ginseng has played a vital role in traditional Chinese medicine for thousands of years. There are 22 variants of ginseng including North American ginseng (Panax quinquefolius) and Asian ginseng (Panax ginseng). The use of North American ginseng has increased dramatically and there is a strong need to understand its immunomodulatory effects. This is because the majority of current research focusing on the Asian ginseng variant. Human peripheral blood mononuclear cells (PBMC) were used to test the immunomodulatory properties of 3 North American ginseng extracts, COLD-FX® and deglycosylated individual ginsenosides. Microarray analysis of PBMC exposed to …