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Alternative and Complementary Medicine Commons™
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Full-Text Articles in Alternative and Complementary Medicine
Measuring The Outcomes Of Therapeutic Listening In Children With Learning And Developmental Disabilities, Hannah Tashjian, Donielle Hair, Phoebe Taasan
Measuring The Outcomes Of Therapeutic Listening In Children With Learning And Developmental Disabilities, Hannah Tashjian, Donielle Hair, Phoebe Taasan
Dissertations, Masters Theses, Capstones, and Culminating Projects
Anecdotal reports of the Therapeutic Listening ®-Quickshifts (TL-Q) technique report positive effects on child behavior but the individualized approach requires further supporting evidence. TL-Q is an individualized sound-based program used to facilitate sensory processing skills and is believed to improve interpersonal, social, and cognitive skills (Frick & Hacker, 2001). This study examines the use of a standardized protocol to measure the specific outcomes of the TL-Q program using a practice-based evidence (PBE) approach for the purpose of aggregating data for clinical practice. The protocol was used to measure the outcomes of the TL-Q program in a convenience sample of 23 …
Identification Of Substrate-Selective Histone Deacetylases And Their Inhibitors That Mediate Her2 Transcript Stability, Mariah Alejo
Identification Of Substrate-Selective Histone Deacetylases And Their Inhibitors That Mediate Her2 Transcript Stability, Mariah Alejo
Dissertations, Masters Theses, Capstones, and Culminating Projects
Breast cancer is the most common malignancy diagnosed in women. 15-20% of these cancers overexpress the HER2 (ERRB2) oncoprotein. HER2-positive breast cancers are generally aggressive and are associated with poor prognosis. Unfortunately, only a mere 30% of HER2-positve patients respond to therapies when they are used as a single agent. Combining therapeutics can potentially lead to synergy and improved anticancer efficacy, and there is clearly a need for the development of new HER2-directed therapeutics. Newer approaches include the utilization of histone deacetylase (HDAC) inhibitors. It has been observed that HDAC inhibitors can induce the rapid decay of oncogenic transcripts such …