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Full-Text Articles in Alternative and Complementary Medicine

Comparative Analysis Of Autologous Chondrocyte Implantation And Other Treatment Modalities: A Systematic Review, Sangeetha Naveen, Noorzurani Robson Associate Prof. Dr., Tunku Kamarul Apr 2011

Comparative Analysis Of Autologous Chondrocyte Implantation And Other Treatment Modalities: A Systematic Review, Sangeetha Naveen, Noorzurani Robson Associate Prof. Dr., Tunku Kamarul

Associate Prof. Dr. Noorzurani Robson

Abstract Purpose: The purpose of this systematic review was to analyze and determine the effectiveness of Autologous Chondrocyte Implantation (ACI) when compared with other treatment modalities which includes microfracture, mosaicplasty, abrasionplasty, bone marrow derived mesenchymal stem cell (BMSC) and matrix assisted autologous chondrocyte implantation (MACI). Methods: Literature search using online databases PubMed, Scopus, National Institute for Clinical Excellence (NICE) and Cochrane Controlled Trial Register regarding all cell based therapies and other interventions for chondral lesions was explored. Data on clinical outcome and repair quality were analyzed. Duplicates and irrelevant articles were omitted. Result: Seventeen (n=17) studies were included in this …


Hepatoprotective Effects Of Orthosiphon Stamineus Extract On Thioacetamide-Induced Liver Cirrhosis In Rats, Mohammed A. Alshawsh, Mahmood A. Abdulla, Ismail Salmah, Zahra A. Amin Jan 2011

Hepatoprotective Effects Of Orthosiphon Stamineus Extract On Thioacetamide-Induced Liver Cirrhosis In Rats, Mohammed A. Alshawsh, Mahmood A. Abdulla, Ismail Salmah, Zahra A. Amin

Mohammed A Alshawsh

Orthosiphon stamineus as medicinal plant is commonly used in Malaysia for treatment of hepatitis and jaundice; in this study, the ethanol extracts were applied to evaluate the hepatoprotective effects in a thioacetamide-induced hepatotoxic model in Sprague Dawley rats. Five groups of adult rats were arranged as follows:Group 1 (normal control group), Group 2 Thioacetamide (TAA) as positive control (hepatotoxic group), Group 3 Silymarin as a well-known standard drug (hepatoprotective group), and Groups 4 and 5 as high and low dose (treatment groups). After 60-day treatment, all rats were sacrificed. The hepatotoxic group showed a coarse granulation on the liver surface …