Medicine and Health Sciences Commons^™

Development Of In Vitro Denture Biofilm Models For Halitosis Related Bacteria And Their Application In Testing The Efficacy Of Antimicrobial Agents, Tingxi Wu, Xuesong He, David J. Bradshaw, Alyson Axe, Zvi G. Loewy, Honghu Liu, Renate Lux

Touro College of Pharmacy (New York) Publications and Research

Objective: Since dentures can serve as a reservoir for halitosis-causing oral bacteria, halitosis development is a concern for denture wearers. In this study, we surveyed the prevalence of four selected halitosis-related species (Fusobacterium nucleatum, Tannerella forsythia, Veillonella atypica and Klebsiella pneumoniae) in clinical denture plaque samples, and developed denture biofilm models for these species in vitro to facilitate assessment of antimicrobial treatment efficacy. Design: Denture plaque from ten healthy and ten denture stomatitis patients was screened for the presence of aforementioned four species by PCR. Biofilm formation by these halitosis-associated species on the surfaces of denture …

Exploring The Process, Models, And Outcomes Of Hospital-Public Health Partnerships, Danielle M. Varda, Jessica H. Retrum, Carrie Chapman

Frontiers in Public Health Services and Systems Research

Health care reform has resulted in changes throughout the health system, including the Affordable Care Act (ACA) requirement that hospitals conduct community health needs assessments, taking into greater consideration the public health of their respective communities. This has led to growing strategies to develop partnerships between hospitals and public health (PH) as a way to meet these needs¹. Meantime, there is a need for data on Hospital-PH partnerships, due to the growing emphasis that these types of partnerships get implemented in practice. In this paper we analyze a secondary data set to explore how hospitals and public health …

Jefferson Digital Commons Quarterly Report: October-December 2014, Daniel G. Kipnis, Msi, Kelsey Duinkerken, Msi

Jefferson Digital Commons Reports

This Jefferson Digital Commons quarterly report will cover the following:

• Assorted statistics
• New assets added to the JDC
• Historical Materials
• What people are saying about the JDC

Today - December 22, 2014, Loma Linda University Health

TODAY

Inside this issue:

-- Loma Linda University Health - San Bernardino launches with $10 million San Manuel gift
-- New dean will lean School of Nursing beginning January 1
-- Children's Hospital celebrates separate licensure
-- Save the date: Zipcar is coming to the campus of Loma Linda University Health
-- Radiothon raises more than $275,000 to battle pediatric cancer
-- Nursing research at LLUMC ends the year on positive note
-- Seeds of Hope event raises $91,000 in support of services provided by Loma Linda University Behavioral Medical Center
-- Annual Spiritual Life and Wholeness Conference to provide inspiration …

Consumer Assessment Of Healthcare Providers And Systems (Cahps) Surveys: Assessing Patient Experience, Lisa Sprague

National Health Policy Forum

This publication provides an overview of the Consumer Assessment of Healthcare Providers and Systems (CAHPS) family of surveys, which are widely used by both public and private health plans and providers to assess the patient's experience of health care. Included is information on survey contents, how surveys are tailored to different users, and how the resulting information is collected, reported, and used to help consumers make choices and providers carry out quality improvement, as well as its role in pay-for-performance reimbursement.

A Microrna-1280/Jag2 Network Comprises A Novel Biological Target In High-Risk Medulloblastoma, Fengfei Wang, Marc Remke, Tze-Chen Hsieh, Lizi Wu, Cynthia Hawkins, Joseph M. Wu, Erxi Wu

NYMC Faculty Publications

Over-expression of PDGF receptors (PDGFRs) has been previously implicated in high-risk medulloblastoma (MB) pathogenesis. However, the exact biological functions of PDGFRα and PDGFRβ signaling in MB biology remain poorly understood. Here, we report the subgroup specific expression of PDGFRα and PDGFRβ and their associated biological pathways in MB tumors. c-MYC, a downstream target of PDGFRβ but not PDGFRα, is involved in PDGFRβ signaling associated with cell proliferation, cell death, and invasion. Concurrent inhibition of PDGFRβ and c-MYC blocks MB cell proliferation and migration synergistically. Integrated analysis of miRNA and miRNA targets regulated by both PDGFRβ and c-MYC reveals that increased …

Periodontal Microorganisms, Obesity, Chronic Inflammation, And Type 1 Diabetes, Georges Joseph Nahhas

Theses and Dissertations

Periodontal disease is a low-grade chronic inflammation in the tissues surrounding the teeth caused by multiple, mostly gram-negative pathogens. It is associated with diabetes, obesity, and chronic inflammation. The specific roles that periodontal microorganism play in these conditions are not well-studied. Hereby, we explored how periodontal bacteria from sub gingival plaque clustered in youth with and without type 1 diabetes, and how such patterns related to body-mass-index percentile (BMI percentile), C-reactive protein (CRP) and adiponectin. Cross-sectional data were collected from 105 youth with type 1 diabetes and 71 without diabetes. Participants were between 12 and 19 years of age receiving …

Weight-Gain And Energy Balance, Benjamin Thomas Gordon

Theses and Dissertations

Energy balance is the result of a dynamic relationship between energy intake (EI), energy expenditure (EE) and energy storage (ES). These three components of energy balance have extremely complicated associations, and all three major components are consistently influenced by physiologic, psychological, and sociologic factors. Concerted changes between EE and EI result in alterations of the ES. Most often in clinical and research settings, bodyweight is used as marker of body composition (i.e., ES) changes. Traditional measurements of bodyweight do not give an accurate portrayal of ES change or the role it has in energy balance. This dissertation supplies new methods …

Mouse Models Of Intervertebral Disc Development, Degeneration And Mechanical Loading, Matthew R. Mccann

Electronic Thesis and Dissertation Repository

Intervertebral disc (IVD) degeneration is a complex and multi-factorial process that is influenced by aging, genetic predispositions and environmental influences, such as altered mechanical loading. While recent studies have begun to characterize changes in the IVD associated with degeneration, the underlying etiology remains elusive. It is thought that the loss of notochord cells from the nucleus pulposus (NP) is one initiating factor contributing to the cascade of disc degeneration. However, questions remain about the function of notochord cells within the disc, including their capacity as tissue specific progenitor cells for the nucleus pulposus. We have demonstrated, with the use of …

Colloidal And Biological Properties Of Triscationic Amphiphiles With One Or Two Tails, John N. Marafino

Masters Theses, 2010-2019

The decline in the development of novel antimicrobials, combined with the misusage and over prescription of antibiotics, has contributed to the increasing prevalence of antimicrobial-resistant infections. Thus development of effective novel disinfectants could reduce the transmission of pathogens and decrease the risk of infection by antibiotic resistant organisms. The antimicrobial activity of amphiphiles, compounds with hydrophobic and hydrophilic regions, was first reported in 1935, and has influenced the synthesis of amphiphiles with variations in structure. In this study, three series of amphiphiles were synthesized by two subsequent Menshutkin reactions. Each amphiphile contains one or two hydrocarbon tails ranging from 8 …

Implementation And Evaluation Of An Oral Hygiene Program In Long-Term Care, Lawrence P. Lemos

Doctor of Nursing Practice (DNP) Projects

A review of the literature focusing on oral care within long-term care (LTC) suggests positive resident care outcomes occur when standardized practices are employed. Studies of staff education programs, trained oral hygiene aides, and dental hygienists working within LTC, have linked regular oral hygiene practices to decreased pneumonia rates. While these studies make the connection between good oral hygiene and reducing risk for pneumonia, best practices focused on implementing and sustaining an oral hygiene program in LTC facilities are lacking. The aim of this quality improvement project was to ensure that dependent residents in LTC receive assistance with daily oral …

Specimen Labeling Improvement Project: Slip, Traci Hoiting

Doctor of Nursing Practice (DNP) Projects

Blood specimens are labeled at the time of acquisition in order to identify and match the specimen, label, and order to the patient. While the labeling process is not new, it is frequently laden with errors (Brown, Smith, & Sherfy, 2011). Wrong blood in tube (WBIT) poses significant risk. Multiple factors contribute to mislabeling errors, including lax policies, limited technological solutions, decentralized labeling processes, multi-tasking, distraction from the clinician, and insufficient education and training of staff. To reduce blood specimen labeling errors, a large academic medical center implemented an innovative technological solution for specimen labeling that integrates patient identification, physician …

Berkeley Youth Alternatives Fieldwork Summary Report: Assessing Social Determinants To Improve The Physical Health And Academic Development For Youth In Berkeley, California, Alane M. Cruz

Master's Projects and Capstones

The following paper summarizes the three hundred hour fieldwork experience at Berkeley Youth Alternatives (BYA), a non-profit community-based organization located in Southwest Berkeley that is committed to combating the social determinants that contribute to the prevalent health disparities within their community. The fieldwork internship is a major requirement in completing the Master’s of Public Health (MPH) program at the University of San Francisco (USF), and allows the education and experience gained over the duration of the program to be applied in a real public health setting.

The overall goal of the internship experience was to assess the social determinants of …

Improving Birth Outcomes: Women’S Oral Health Project, Dilem Polat

Master's Projects and Capstones

Improving Birth Outcomes: Women’s Oral Health Project is a new project housed within the Child Health and Disability Prevention, CHDP Program. The main goal of the project is to improve the birth outcomes of high-risk pregnant women and their children, by educating participants within the Maternal Child and Adolescent Health Section at the San Francisco Department of Public Health. The educational component will focus on the importance of oral health and the impact of oral disease on perinatal health. Following the educational component, referrals for appropriate dentists will be provided for participants to they may begin improving their oral health. …

Addressing Health Disparities In Refugees, Claire E. Lopez

Master's Projects and Capstones

I completed the required 300 hours of my fieldwork internship at the International Rescue Committee (IRC) in Oakland, CA. The International Rescue Committee (IRC) is a non-profit international organization that responds to the world’s worst humanitarian crises and aids displaced individuals in rebuilding their lives in new countries by providing support in health care, finance, education, infrastructure, and resettlement.

I worked as a Health Access/Intensive Case management Intern. As a Health Access Program Intern, it was my job to ensure that refugees coming to the United States had a place to seek medical care, advice, and preventative services. In order …

The Role Of An International Cross Cultural Interprofessional Healthcare Immersion Program In Doctor Of Physical Therapy Education: An Educational Case Report, Jayme Keith

Case Report Papers

Background and Purpose: Today’s healthcare team requires providers to be culturally sensitive and competent interprofessional collaborators. Interprofessional Education (IPE) helps to provide a collaborative foundation for healthcare providers. Cross-cultural immersion (CCI) educational programs foster cultural awareness. Service-learning (SL) programs create opportunities for students to have interprofessional and cross cultural experiences. The purpose of this educational case report is to describe an interprofessional international cross-cultural immersion healthcare program and to discuss the role of this program in the development of (DPT) students’ cultural competence, interprofessionalism, and social responsibility. Case Description: The Ghana Cross Cultural Healthcare Immersion (GCCHI) is a University based …

Evidence-Based Change In Practice: Development And Implementation Of Type Ii Diabetic Flow Sheet, Kathryn Grimleybaker

Doctor of Nursing Practice (DNP) Projects

Ten percent of the National Health Service annual budget goes to treat complications from diabetes (Lancet, 2010). The American Diabetes Association® (ADA, 2013) estimated that diabetics in the United States incur $176 billion annually in direct medical costs for treatment with hospitalization being the main component of the expenditures. California has the largest population of diabetics and the highest annual cost at $27.6 billion (ADA, 2013). The Healthcare Cost and Utilization Project (HCUP, 2008) found that the average cost of hospitalization in 2008 for a patient with diabetes was $10,937 in contrast to $8,746 for a patient without diabetes. The …

Ada News - 12/08/2014, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Careers In Quality Panel, Joseph M. Montella, Md, Ms, Cpe (Moderator And Panel Speaker), Lawrence D. Ward, Md, Mph, Facp, Robert M. Dressler, Md, Mba, Marina V. Zeltser, Md, Mba

Future Leaders in Quality and Safety

No abstract provided.

Interview With Ritsu Komaki, Ritsu Komaki Md, Facr, Fastro

Texas Medical Center - Women's History Project

An oral history interview with Ritsu Komaki.

An Assessment Of What Factors Affect The Average Number Of Caries Seen Per Visit Among Children Visiting A Mobile Dental Unit In South Central Kentucky, Breion Douglas

Mahurin Honors College Capstone Experience/Thesis Projects

Background: Dental caries is the single most common chronic childhood disease in Kentucky affecting 20% of preschoolers, 50% of second graders, and 75% of 15 year olds. Dental caries, also known as tooth decay, occurs when bacteria from salivary glands produce an acid to breakdown food. If this acid is not cleaned off the teeth, it can destroy the tooth enamel. Dental problems can be linked to the inability to pay for dental care (i.e. insurance), limited access to dental providers, and parental inability to take their children to dentists. To help address the issue with tooth decay seen among …

Regulation Of Crfr1 And 5-Ht2ar By Pdz Domain-Containing Proteins Sap97 And Psd-95, Henry A. Dunn

Electronic Thesis and Dissertation Repository

Previous studies identified a crosstalk mechanism whereby CRFR1 sensitized 5-HT_2AR-mediated signaling via interactions with PDZ domain-containing proteins: a mechanism that may underlie stress-induced anxiety and depression. This prompted an investigation into uncovering which PDZ domain-containing proteins could regulate the crosstalk between these two receptors, and how they could be regulated individually. In the current studies, a subset of PDZ domain-containing proteins were identified that may interact with CRFR1 and 5-HT_2AR. The focus narrowed to two candidates previously implicated in psychiatric disease: SAP97 and PSD-95. We confirmed SAP97 and PSD-95 as interacting partners of CRFR1 in adult …

The Relationship Between Pain Sensitivity And Motor Adaptations, Irina Fedulow, Katherine S. Rudolph

Research Report Papers

The purpose of this study is to investigate the relationships between measures of central sensitization and CPM and how they impact motor adaptations in individuals without chronic pain conditions. To conduct this research, we decided to incorporate the “broken escalator phenomenon,” which is the unusual feeling that occurs when an individual steps onto an escalator or moving walkway that is broken and therefore not moving. The body responds with an anticipatory response that includes increased trunk sway and increased forward speed. The body adapts to the stationary walkway by reducing trunk sway and speed. Following that period of adaptation, if …

Compulsory Water Fluoridation: Justifiable Public Health Benefit Or Human Experimental Research Without Informed Consent?, Rita Barnett-Rose

William & Mary Environmental Law and Policy Review

No abstract provided.

Nutrition-Related Conditions Among Children Of Migrant And Seasonal Farmworkers In The United States: Causes And Solutions, Rebecca Halvorson

Food Science and Nutrition

The purpose of this literature review is to determine the prevalence of nutrition-related conditions among children of migrant and seasonal farmworkers (MSFW) compared to national averages, as well as effectiveness of strategies for minimizing any health discrepancies. MSFW live under harsh conditions, engage in long hours of physically demanding labor, and receive insufficient income. Compounding demographic characteristics create insurmountable barriers to quality health care and nutrition education resulting in disproportionately unhealthy children within the MSFW population as compared to the greater US population. The prevalence of overweight, obesity, diabetes mellitus, cardiovascular disease, and numerous infections is higher among MSFW children. …

On The Symbolism Of The White Coat, David A. Nash

Oral Health Science Faculty Publications

The white coat ceremony has become an academic ritual in the health professions: a ceremony that signals a transformation of status from ordinary student to that of one studying to become a health professional. While donning the white coat is a sign of a changed role, the white coat is also a powerful symbol of transformation. White is a symbol of purity, and the white coat symbolizes the purity of purpose being affirmed in becoming a health professional. Dentistry is afforded the status of a learned profession as a result of the power dentists possess over patients seeking care; this …

Synthesis And Characterization Of Methacrylated Hyaluronan-Based Hydrogels For Tissue Engineering, Keegan Bradley Compton

Theses and Dissertations (ETD)

Polymers have revolutionized the field of tissue engineering due to the countless possibilities of scaffolds that can be constructed from such a material. Through conjugation of other functional groups onto a polymer backbone, the mechanical properties of polymers can be controlled and has the ability to span a wide range of strengths, allowing for application in multiple tissue environments. One such polymer, hyaluronic acid (HA), is a natural polysaccharide found most abundantly in the extracellular matrix (ECM) of connective tissues with structural, lubricating, and wound healing functions in the human body; for this reason, HA has great potential for utilization …

Designing A Mechanical Linkage Capable Of Decreasing Force Transfer From The Facemask To The Protective Helmet When Loading Occurs, Levi Hansen

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction

Sports that involve extensive personal contact have a high incidence of injury. The introduction of regulations mandating the use of personal protective equipment in these sports is the most common injury control strategy (Marshall et al., 2002). Negligible attention has been paid to the mechanical linkage between the facemask and helmet as a means of reducing force transfer from the facemask, through the helmet, and to the head and or neck of the athlete.

Methods

A novel prototype mechanical linkage of reasonable simplicity that provides 360° of freedom in motion capable of decreasing force transfer from the facemask to …

Induction Of Differentiation Of Dental Pulp-Derived Mesenchymal Stem Cells (Dpsc), Aubrey Young

UNLV Theses, Dissertations, Professional Papers, and Capstones

Mesenchymal stem cells are derived from a variety of human tissues and are being bioengineered and studied for possible uses in the advancement of medicine. Recent efforts are being focused on Dental Pulp Stem Cells (DPSC's) due to the accessibility of this tissue. Many factors influence DPSC quality and quantity, including the specific methods used to isolate, collect, concentrate, and store these isolates once they are removed. Ancillary factors, such as the choice of media, the selection of early versus late passage cells, and cryopreservation techniques may also influence the differentiation potential and proliferative capacity of DPSC isolates.

The objective …

Fluorescence-Controlled Er:Yag Laser For Caries Removal In Permanent Mandibular Molars, Douglas Nartker, Suzie Oh, Shefat Rabbi, Jonathan Schneider

Dental Medicine Student Research Posters

Poster presentation of research proposal addressing the question: Do fluorescence-controlled Er:YAG lasers more effectively remove dentinal carious hard tissue on permanent mandibular molars than conventional rotary burs?