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Full-Text Articles in Medicine and Health Sciences

A Baker's Dozen Of Top Antimicrobial Stewardship Intervention Publications In 2019, Kayla R Stover, Elias B Chahine, David Cluck, Sarah Green, Daniel B Chastain, Darrell Childress, Carmen Faulkner-Fennell, Katherine Lusardi, Edo-Abasi U. Mcgee, Michelle Turner, P Brandon Bookstaver, Christopher M Bland Oct 2020

A Baker's Dozen Of Top Antimicrobial Stewardship Intervention Publications In 2019, Kayla R Stover, Elias B Chahine, David Cluck, Sarah Green, Daniel B Chastain, Darrell Childress, Carmen Faulkner-Fennell, Katherine Lusardi, Edo-Abasi U. Mcgee, Michelle Turner, P Brandon Bookstaver, Christopher M Bland

PCOM Scholarly Papers

Staying current on literature related to antimicrobial stewardship can be challenging given the ever-increasing number of published articles. The Southeastern Research Group Endeavor (SERGE-45) identified antimicrobial stewardship-related peer-reviewed literature that detailed an actionable intervention for 2019. The top 13 publications were selected using a modified Delphi technique. These manuscripts were reviewed to highlight the actionable intervention used by antimicrobial stewardship programs to provide key stewardship literature for teaching and training and to identify potential intervention opportunities within one's institution.


Interleukin 1Β And Prostaglandin E2 Affect Expression Of Dna Methylating And Demethylating Enzymes In Human Gingival Fibroblasts, Sara Seutter, Jacquay Winfield, Alexis Esbitt, Samantha Snyder, Anastasia Magner, Kristine Kim, Craig Carcuffe, Jeremy Schmoyer, Payvand Kamrani, Jason Mercando, Seyed M Shamseddin, Kevan Green, Ruth C. Borghaei Jan 2020

Interleukin 1Β And Prostaglandin E2 Affect Expression Of Dna Methylating And Demethylating Enzymes In Human Gingival Fibroblasts, Sara Seutter, Jacquay Winfield, Alexis Esbitt, Samantha Snyder, Anastasia Magner, Kristine Kim, Craig Carcuffe, Jeremy Schmoyer, Payvand Kamrani, Jason Mercando, Seyed M Shamseddin, Kevan Green, Ruth C. Borghaei

PCOM Scholarly Papers

Periodontitis is a common chronic inflammatory condition that results in increased levels of inflammatory cytokines and inflammatory mediators. In addition to oral disease and tooth loss, it also causes low-grade systemic inflammation that contributes to development of systemic conditions including cardiovascular disease, pre-term birth, diabetes and cancer. Chronic inflammation is associated with epigenetic change, and it has been suggested that such changes can alter cell phenotypes in ways that contribute to both ongoing inflammation and development of associated pathologies. Here we show that exposure of human gingival fibroblasts to IL-1β increases expression of maintenance methyltransferase DNMT1 but decreases expression of …