Medicine and Health Sciences Commons^™

Impact Of An Adaptive Worksite Diabetes Prevention Trial On Health Action Process Approach Outcomes Regarding Dietary Intake And Physical Activity, Danielle E. King, Carla K. Miller, Haikady N. Nagaraja, Kentaro Fujita, Jennifer S. Cheavens

Health Behavior Research

Weight loss, through a reduction in energy intake and increase in energy expenditure, can reduce diabetes risk in people with prediabetes. However, lifestyle change can be challenging even with positive intentions. The Health Action Process Approach (HAPA) theoretical framework bridges the intention-behavior gap by targeting planning behaviors and strengthening efficacious beliefs for behavioral change. In the current trial, an adaptive design was employed to examine differences in HAPA measures (i.e., planning and self-efficacy) regarding the target behaviors of dietary intake and physical activity (PA). Adults ≥ 21 years old with overweight or obesity and prediabetes (n = 185) received the …

Lap-Bands, A Complication, Peter Aziz, Micah Mabe

Tower Health Research Day

No abstract provided.

Action Apac: Understanding Perceptions, Attitudes And Behaviours In Obesity And Its Management Across South And Southeast Asia, Kwang Wei Tham, Asma Ahmed, Apussanee Boonyavarakul, Mariana Mercado Garcia, Miroslava Guajardo, Zubaidah Nor Hanipah, Tran Quang Nam, Nemencio A. Nicodemus, Faruque Pathan, Jack Garcia Uranga Romano, Sidartawan Soegonda, Edgardo L. Tolentino, Ambika Gopalakrishnan (A G) Unnikrishnan, Brian J. Oldfield

Ateneo School of Medicine and Public Health Publications

To identify perceptions and attitudes among people with obesity (PwO) and healthcare professionals (HCPs) toward obesity and its management in nine Asia-Pacific (APAC) countries, a cross-sectional online survey was conducted among adult PwO with self-reported body mass index of ≥25 kg/m2 (≥27 kg/m2, Singapore), and HCPs involved in direct patient care. In total, 10 429 PwO and 1901 HCPs completed the survey. Most PwO (68%) and HCPs (84%) agreed that obesity is a disease; however, a significant proportion of PwO (63%) and HCPs (41%) believed weight loss was the complete responsibility of PwO and only 43% of PwO discussed weight …

Incorporation Of Nutrition Education With Medication Inject To Sustain Weight Loss, Julia Calvelo

Nursing | Student Research Posters

Nationwide prevalence of obesity is related to comorbidities including heart disease, type 2 diabetes, and stroke. The United States spends nearly $173 billion annually for the medical cost of obesity, and obese adults have a difference of $1,861 of medical costs than those with healthy weight (CDC, 2022). Overweight individuals experience chronic health issues, resuling in a significant financial burden due to increased costs associated with medical treatment. Ozempic is a newly approved drug accepted by the FDA in 2017 to treat diabetes but is now gradually being implemented as a weight loss medication. It is used in conjunction with …

The Role Of Primary Care Providers In Maintaining Weight Loss By Preventing Behavioral Relapse, Hayden R. Blanchard

Capstone Showcase

Supporting patients in optimizing health by treating obesity remains a relevant goal for primary care providers. While weight loss is frequently achieved with behavioral modification, maintaining weight loss by avoiding behavioral relapse is much more difficult. Patient may lose weight by reducing overall energy intake, incorporating intensive behavior change programs, utilizing pharmacotherapy as needed and, in certain cases, undergoing bariatric surgery. With a focus on behavior change and maintenance, primary care providers can support patients by planning more frequent follow up appointments, at least every one to three months. In these visits, PCPs can: focus on reenforcing lifestyle change principles …

Ozempic (Semaglutide) Versus Nonpharmacologic Interventions For Weight Management In Overweight Individuals, Elena N. Jacey, Lily Jennings, Callie Gillmore, Emily Kane, Emma Digirolamo

Non-Thesis Student Work

Ozempic (semaglutide) is a medication prescribed for individuals managing Type 2 Diabetes Mellitus by mimicking the action of a hormone called GLP-1, helping to regulate glucose levels by stimulating insulin secretion and reducing glucagon secretion. Many patients with Type 2 Diabetes Mellitus rely on Ozempic (semaglutide) as a weight loss aid as opposed to implementing healthy lifestyle changes. This information proposes the question: in overweight individuals taking Ozempic (semaglutide), a medication prescribed for those with Type 2 Diabetes Mellitus, for the management of weight loss, does the use of Ozempic (semaglutide) compared to non-pharmacologic weight loss strategies exaggerate the occurrence …

The Effectiveness Of Jeffwlp For Weight Loss And General Nutritional Knowledge In Obese Patients, Scott Kozarsky, Ba, Olivia Ackley, Bs, Cynthia Cheng, Md, Phd

Alpha Omega Alpha Research Symposium Posters

PURPOSE: The increasing prevalence of obesity urgently requires effective management strategies. This study evaluates the effectiveness of Jefferson Weight Loss Program (JeffWLP), a trained medical student-delivered health education program in a predominantly African-American patient cohort.

METHODS: A randomized controlled trial was performed enrolling 30 patients with an average socioeconomic status of 5.8 (10 maximum). The intervention group (n=18) completed JeffWLP, a low-cost, 12-week health coaching program combining education sessions with graded step exercises. The control group (n=12) received usual care. Mean baseline age, BMI, and General Nutritional Knowledge Questionnaire (GNKQ) scores were: 46±13 years, 38±5, and 14.7±1.9 (maximum score=17) respectively. …

Incorporation Of Nutrition Education With Medication Injection To Sustain Weight Loss, Julia Calvelo

Nursing | Senior Theses

Background: Obesity is a widespread occurrence linked to comorbidities. Weight loss and maintenance is crucial to sustain existing health conditions and reduce risk of chronic diseases.

Lack of maintained weight loss is associated with poor education on nutrition, diet, and physical activity literacy. Objective: The purpose of this quantitative experimental study is to determine the efficacy of nutrition education among medication injection to sustain weight loss throughout treatment. It aims to promote comprehension of the aspects of nutrition, dietary habits, and physical education to not only sustain weight loss, but to understand the significance of how these elements contribute to …

Weight Loss In Obese Adults On The Ketogenic Diet, Abigail Velasquez

Master of Science in Nursing Family Nurse Practitioner

The ketogenic diet is a successful and sustainable diet for obese adults to lose weight. One aim of this project is to provide evidentiary support for the ketogenic diet. An additional aim is to disseminate up to date literature to primary care providers in order to offer the ketogenic diet as a sustainable option for weight loss, to reverse disease risk, and, essentially, regain optimal health.

The Potential Weight Loss Benefits Of Tirzepatide: A Double-Edged Sword?, Muhammad Taha Nasim, Ayesha Ali, Muhammad Tabish Nasim

Medical College Documents

No abstract provided.

The Ups And Downs Of Weight Cycling: How Fad Diets Can Negatively Affect Health, Catherine Jasper

BUHealth

It’s advice nearly every patient has heard at least once in their life: you need to lose weight. Often, this is prescribed as a combination of a healthy diet and exercise. However, ‘fad diets’, so-called due to their fluctuating popularity from societal trends, are seen as quick and easy diet modifications that produce weight loss quickly. For some, these diets are not sustainable and can lead to dangerous cycles of losing weight, easing restrictions, and re-gaining weight that was lost. Weight-cycling is a dangerous effect of fad diets, and the long-term physical and psychological effects of weight cycling can ultimately …

Topiramate (Topamax): Evolving Role In Weight Reduction Management: A Narrative Review, Irza Wajid, Alexis Vega, Katherine Thornhill, Jack Jenkins, Chandler Merriman, Debbie Chandler, Sahar Shekoohi, Elyse M. Cornett, Alan D. Kaye

School of Medicine Faculty Publications

Obesity has emerged as a widespread disease with epidemic proportions, necessitating effective management to enhance the overall health outcomes of patients. Medical intervention for weight loss becomes necessary when diet and exercise prove ineffective, and topiramate emerges as a potential treatment option for this global problem. Currently approved as an anti-epileptic and migraine prophylaxis medication, topiramate is frequently utilized as adjunctive therapy for patients with mood and eating disorders, as well as for alcohol use disorders. Its multifaceted mechanisms of action contribute to reducing neuronal excitation and enhancing neuronal inhibition. Given its variety of mechanisms, topiramate shows several off-label outcomes, …

Weight Cutting In Female Ufc Fighters, Cassandra Evans, Charles Stull, Gabriel Sanders, Anthony A. Ricci, Duncan French, Jose Antonio, Corey Peacock

HPD Articles

It is common practice for fight sport athletes to use a variety of weight manipulation strategies to compete in desired weight classes. Although numerous studies have highlighted rapid weight loss (RWL) strategies and the magnitude of weight loss, few have focused specifically on weight loss in female fighters. The purpose of this study was to provide descriptive information on professional UFC female fighters engaging in RWL in all women’s UFC weight divisions: strawweight (52.2 kg): flyweight (56.7 kg); bantamweight (61.2 kg); featherweight (65.8 kg).

Dietary Intake During A Pragmatic Cluster-Randomized Weight Loss Trial In An Underserved Population In Primary Care, John W. Apolzan, Corby K. Martin, Robert L. Newton, Candice A. Myers, Connie L. Arnold, Terry C. Davis, William D. Johnson, Dachuan Zhang, Christoph Höchsmann, Vivian A. Fonseca, Kara D. Denstel, Emily F. Mire, Benjamin F. Springgate, Carl J. Lavie, Peter T. Katzmarzyk, Phillip Brantley, Ronald Horswell, Tina K. Thethi, Jonathan Gugel, Eboni Price-Haywood, Kathleen B. Kennedy, Daniel F. Sarpong

School of Medicine Faculty Publications

Background: Currently there are limited data as to whether dietary intake can be improved during pragmatic weight loss interventions in primary care in underserved individuals. Methods: Patients with obesity were recruited into the PROPEL trial, which randomized 18 clinics to either an intensive lifestyle intervention (ILI) or usual care (UC). At baseline and months 6, 12, and 24, fruit and vegetable (F/V) intake and fat intake was determined. Outcomes were analyzed by repeated-measures linear mixed-effects multilevel models and regression models, which included random cluster (clinic) effects. Secondary analyses examined the effects of race, sex, age, and food security status. Results: …

Benchmark: Impact Of Weight Loss Education On Obese Patients, Tabitha A. Moorehead

MSN Capstone Projects

Objective: With an epidemic as severe as obesity, it is paramount that healthcare professionals be aware of the overarching negative effects the disease can contribute to the human body. If constructive dialogue can be achieved between patient and provider without suspicion of bias or judgment, we would potentially experience an elevated willingness of patients to follow treatment steps.

Background: According to the World Health Organization (WHO), worldwide obesity has nearly tripled since 1975. “Most of the world's population live in countries where overweight and obesity kills more people than underweight” (WHO, 2021). “More than 4 in 10 Americans are …

Liraglutide Versus Semaglutide: Long Term Weight Loss Management In Obese Individuals, Mckenzie Burke

Physician Assistant Scholarly Project Papers

Obesity has been a source of complications affecting multiple aspects from a physiological and psychological standpoint which has been steadily growing. There are a multitude of weight loss programs and medications with the idea of sustaining consistent weight loss to include use of the pharmaceuticals discussed within this review. The purpose of this literature review is to compare the efficacy and safety with use of liraglutide versus semaglutide (GLP-1 receptor agonists) in respect to long term weight loss management while in conjunction to lifestyle modifications within the obese population. Thorough research has been done with the aid of health science …

Cardiometabolic Risk Factors Efficacy Of Semaglutide In The Step Program, Anastassia Amaro, Neil S. Skolnik, Danny Sugimoto

Abington Jefferson Health Papers

People with overweight or obesity often suffer from associated cardiometabolic diseases and comorbidities. Current therapies for obesity include lifestyle intervention, bariatric surgery, and pharmacotherapy. The magnitude of weight loss achieved with these therapies can determine the level of improvement in various comorbidities. Once-weekly subcutaneous semaglutide 2.4 mg is a glucagon-like peptide-1 receptor agonist recently approved by the US Food and Drug Administration for the treatment of obesity. This article reviews data from the global phase 3 Semaglutide Treatment Effect in People with obesity (STEP) program, comparing the efficacy of once-weekly subcutaneous semaglutide 2.4 mg versus placebo for weight loss and …

The Experiences Of Middle-Aged Women In An Online Weight-Loss Community, Holly Fields

Walden Dissertations and Doctoral Studies

The obesity epidemic continues to be a public health crisis in the United States. The number of obese middle-aged women has risen dramatically over the past few decades. Despite multiple levels of support available, not all women are receiving the support they need to reduce overweight/obesity, as evidenced by the continuing rise in obesity. Using a qualitative phenomenological approach, this study examined middle-aged women's views on exercising, eating healthily, and social support in online weight-loss communities. For this study, the health belief model (HBM) and social learning theory (SLT) were used as conceptual frameworks to understand a person's behavioral intentions …

Pre–Post Intervention Exploring Cognitive Function And Relationships With Weight Loss, Intervention Adherence And Dropout, Amanda N. Szabo-Reed, Laura E. Martin, Cary R. Savage, Richard A. Washburn, Joseph E. Donnelley

Center for Brain, Biology, and Behavior: Faculty and Staff Publications

Objective: To evaluate the association between baseline cognitive function, intervention dropout, adherence and 3-month weight loss (WL) when controlling for confounding demographic variables.

Methods: 107 (Mage = 40.9 yrs.), BMI in the overweight and obese range (BMI = 35.6 kg/m2), men (N = 17) and women (N = 90) completed a 3-month WL intervention. Participants attended weekly behavioral sessions, comply with a reduced calorie diet, and complete 100 min of physical activity (PA)/wk. Cognitive function tasks at baseline included Flanker (attention), Stroop (executive control) and working memory, demographics, body weight and cardiovascular fitness were assessed at baseline. Session attendance, adherence …

A Healthier Diet For Weight Loss, Hannah White

Family Medicine Clerkship Student Projects

Many patients presenting to clinic have the goal of weight loss to improve their health as obesity has many comorbidities. Many patients have multiple health concerns like Diabetes Mellitus, Hypertension, Hyperlipidemia, PCOS, or joint pain. Part of the management of their conditions include weight loss, but many patients struggle, for years, to lose weight. A referral to the Metabolic Weight Loss clinic in Newtown, which will provide patients with nutritional information, evidence based diets, medications, exercises, and more, can take up to 1 year to get an appointment. The goal of this project is to provide information to patients in …

Weight Cutting In Female Ufc Fighters, Cassandra Evans, Charles Stull, Gabriel Sanders, Anthony Ricci, Duncan French, Jose Antonio, Corey A. Peacock

Research outputs 2022 to 2026

Background: It is common practice for fight sport athletes to use a variety of weight manipulation strategies to compete in desired weight classes. Although numerous studies have highlighted rapid weight loss (RWL) strategies and the magnitude of weight loss, few have focused specifically on weight loss in female fighters. The purpose of this study was to provide descriptive information on professional UFC female fighters engaging in RWL in all women’s UFC weight divisions: strawweight (52.2 kg): flyweight (56.7 kg); bantamweight (61.2 kg); featherweight (65.8 kg). Methods: All fighter’s weights were obtained at five separate time points: 72 hrs. pre-weigh-in, 48 …

Impact Of Dietary Walnuts, A Nutraceutical Option, On Circulating Markers Of Metabolic Dysregulation In A Rodent Cachectic Tumor Model, Lauri O. Byerley, Hsiao Man Chang, Brittany Lorenzen, Jessie Guidry, W. Elaine Hardman

School of Medicine Faculty Publications

Background: Nutraceutical foods, like walnuts which are rich in immunonutrients, can have medicinal benefits. Dietary walnuts have been shown to slow or prevent tumor growth in mice genetically programmed to grow breast or prostate tumors. This study investigated whether walnuts could exert the same preventable effect in a transplantable carcinoma rat model. Methods: Eighteen rats were randomly fed a diet containing walnuts (10% of food by weight), and 36 were fed a diet without walnuts (control) for 21 days. On day 22, 18 control diet rats were switched to the walnut diet. All other animals remained on their same diet. …

The Role Of Emotion Regulation In Long-Term Weight Loss Maintenance: A Cross-Sectional Study, Karyn M. Aiello

Graduate Masters Theses

While many weight loss interventions have resulted in significant weight loss, maintaining that weight loss long-term continues to be challenging for most, with long-term weight loss maintenance (LTWLM) rates as low as 20% among participants of clinical weight loss studies. Those who struggle with LTWLM exhibit many shared characteristics, including lower mental health composite scores; high levels of perceived stress; and lower rates of adherence to WLM behaviors. One explanation for this might be that emotion regulation (ER) skills are stronger among those who are successful at LTWLM, and therefore more successful at self-regulating for the goal of LTWLM.

The …

Lisdexamfetamine Is An Effective Monotherapy For Moderate To Severe Binge Eating Disorder, Benjamin Young

Clinical Research in Practice: The Journal of Team Hippocrates

A clinical decision report using

McElroy SL, Hudson J, Ferreira-Cornwell MC, Radewonuk J, Whitaker T, Gasior M. Lisdexamfetamine dimesylate for adults with moderate to severe binge eating disorder: Results of two pivotal phase 3 randomized controlled trials. Neuropsychopharmacology. 2016;41(5):1251-1260. https://doi.org/10.1038/npp.2015.275

for a young woman requesting a novel pharmacological intervention for a Binge Eating Disorder (BED).

Dietary Supplements In People With Metastatic Cancer Who Are Experiencing Malnutrition, Cachexia, Sarcopenia, And Frailty: A Scoping Review, Jolyn Johal, Chad Yixian Han, Ria Joseph, Zachary Munn, Oluwaseyifunmi Andi Agbejule, Fiona Crawford‐Williams, Matthew P. Wallen, Raymond J. Chan, Nicolas H. Hart

Research outputs 2022 to 2026

Cancer‐associated malnutrition, or cachexia, stemming from cancer or its treatments, is particularly prevalent in metastatic cancers, and is often interrelated with sarcopenia and frailty. Evidence suggests that dietary supplements play a role in managing these conditions. As metastatic cancer cells are associated with notable genomic and phenotypic alterations, response to dietary supplements may differ between metastatic and non‐metastatic cancers. However, research in this area is lacking. This scoping review aims to identify the dietary supplements that have been studied in patients with metastatic cancers and malnutrition‐related conditions, along with their proposed effects, mechanisms, outcome measures, and tools used. A systematic …

Diet, Exercise, Self-Monitoring, Technology, And Motivational Interviewing For Weight Loss In Adults, Ashleigh D. Warburton

Evidence-Based Practice Project Reports

Obesity, an epidemic in the United States (US), affected 42.4% of adults as of 2017-2018 (Hales, 2020). Comorbidities associated with obesity, such as cardiovascular disease, cancer, and diabetes (Orringer et al., 2020), are some of the leading causes of death in the US (Kochanek et al., 2020). The purpose of this evidence-based practice (EBP) project was to answer the following PICOT question: In adult patients aged 19 years or older who are considered overweight or obese as measured by body mass index (BMI) of ≥ 25 kg/m2 (P), how effective is diet and exercise combined with self-monitoring, a phone application, …

Health Equity & Obesity Management: An Improvement Project In A Federally Qualified Healthcare Center In Central Harlem, Brianna Bouchez

Doctor of Nursing Practice Scholarly Projects

Description of the problem: Obesity is a growing healthcare problem worldwide with extraordinary costs to the individual's health and the healthcare system. Individuals most affected by obesity include socioeconomically disadvantaged individuals, often with limited resources to seek specialized care.

Available knowledge: Various weight-loss interventions exist but access and success rates vary. Weight loss is often modest and additional factors such as social determinants of health, health literacy, and patient motivation are all factors important to the success of an intervention.

Specific Aims: The purpose of this quality improvement project was to improve self-regulatory weight loss behaviors and increase weight loss …

Dnp Final Report: Physical Activity In Bariatric Surgery Patients: An Evidence-Based Quality Improvement Project, Amber Buehler

DNP Final Reports

Background: Research evidence supports that increasing physical activity has been shown to reduce weight and prevent weight regain after bariatric surgery. There is currently no specific exercise recommendation or program at the Center for Metabolic and Weight Loss Surgery at Dallas.

Objective: To implement an evidence-based project surrounding physical activity to reduce weight regain in patients 12 months post bariatric surgery.

Methods: The 12-week program will consist of 3 times weekly 1 hour virtual exercise classes led by the Nurse Practitioner and/or Nurse. Patients will be screened for current physical activity via survey using the IPAQ at the beginning and …

Association Of Gut Metabolomic Biomarkers With Sleeve Gastrectomy Weight-Loss Outcomes, Pamela Spicer, Wendy Miller, Kathryn Ziegler, Stewart Graham

Posters

INTRODUCTION
Obesity is a prevalent health challenge with high morbidity and many associated chronic diseases. Sleeve gastrectomy is currently the predominant intervention for obesity. However, weight loss results are variable. The mechanisms and factors influencing this variability are not well understood. We evaluated the correlation of metabolomic biomarkers with weight-loss.

Efficacy Of Probiotic Supplementation For Weight Loss In Overweight And Obese Adults, Kelsie Tescher

Physician Assistant Scholarly Project Papers

The purpose of this literature review is to assess current studies investigating the efficacy of using probiotic supplementation to promote weight loss in the overweight and obese adult populations. Three databases were used including PubMed, ClinicalKey, and Embase with a time frame of 15 years. A total of 17 studies met the research criteria and were therefore reviewed. Body weight loss and decrease in BMI were used as measurements of efficacy. Studies used were peer reviewed, randomized-control trials, double-blind, and placebo-controlled. Current research shows insufficient evidence to support the use of a specific genus and/or species of probiotic to promote …