Medicine and Health Sciences Commons^™

Pulsed-Dye Laser Efficacy In The Treatment Of Psoriasis In Adult Patients: An Evidence-Based Case Report, Made Ananda Krisna, Hanny Nilasari

Journal of General - Procedural Dermatology & Venereology Indonesia

Psoriasis is a chronic inflammatory skin disease known to be highly responsive to phototherapy. Narrow-band UVB (NBUVB) phototherapy has been one of the standard treatments for its moderate to severe form. However, its lack of efficacy in treating stable psoriatic plaques on extremities has lead researchers to find alternative treatments, one of which is pulsed-dye laser (PDL). Laser has been known to be effective in treating vascular lesions; in psoriasis, elongation of rete ridge along with tortuous dermal capillaries are one of the first pathologies identified early in the disease progression. Several in vivo and preliminary studies have found the …

Diagnosis And Treatment Of Acquired Hemophilia A (Aha) With Bullous Pemphigoid, Rasco Sandy Sihombing, Henry Ratno Diono Silalahi, Hamzah Shatri, Lugyanti Sukrisman, Ikhwan Rinaldi, Findy Prasetyawati, Endy Novianto, Em Yunir

Jurnal Penyakit Dalam Indonesia

No abstract provided.

Simplified Antibiotic Regimens For Treatment Of Clinical Severe Infection In The Outpatient Setting When Referral Is Not Possible For Young Infants In Pakistan (Simplified Antibiotic Therapy Trial [Satt]): A Randomised, Open-Label, Equivalence Trial, Fatima Mir, Imran Nisar, Shiyam S. Tikmani, Benazir Baloch, Sadia Shakoor, Fyezah Jehan, Imran Ahmed, Simon Cousens, Anita K M Zaidi

Department of Paediatrics and Child Health

Background: Parenteral antibiotic therapy for young infants (aged 0–59 days) with suspected sepsis is sometimes not available or feasible in countries with high neonatal mortality. Outpatient treatment could save lives in such settings. We aimed to assess the equivalence of two simplified antibiotic regimens, comprising fewer injections and oral rather than parenteral administration, compared with a reference treatment for young infants with clinical severe infection.
Methods: We undertook the Simplified Antibiotic Therapy Trial (SATT), a three-arm, randomised, open-label, equivalence trial in five communities in Karachi, Pakistan. We enrolled young infants (aged 0–59 days) who either presented at a primary health-care …

The Association Of Nurses’ Assessment And Certainty To Pain Management And Outcomes For Nursing Home Residents In Jordan, Mohammad Jamil Rababa

Theses and Dissertations

Despite advances in dementia care Pain in people with dementia is still under recognized, underestimated, and undertreated because of poor assessment, poor treatment, and factors relating to nurses’ critical thinking and decision-making skills. Unrelieved pain leads to many serious negative health outcomes in people with dementia. The purpose of the study was to examine temporally based relationships between change in behavior, the nurses’ level of certainty regarding pain, assessment scope and outcomes of pain and agitation. Relationship between severity of dementia, comorbid burden, ability to verbally self-report symptoms and patient outcomes of pain and agitation was also investigated.

A Convenient …

Availability Of Buprenorphine Treatment In Kentucky, Elijah T. Myers, Tyrone F. Borders

Institute for Rural Health Policy Reports

Drug overdose and substance use treatment admissions data indicate that opioid use is problematic in Kentucky, but little information exists about the geographic availability of buprenorphine treatment across the state. Furthermore, there is even less information about the characteristics of the physicians prescribing buprenorphine. This report describes the availability of buprenorphine treatment in Kentucky.

Using Survival Analysis To Identify Risk Factors For Treatment Interruption Among New And Retreatment Tuberculosis Patients In Kenya, Enos O. Masini, Omar Mansour, Clare E. Speer, Vittorio Addona, Christy L. Hanson, Joseph K. Sitienei, Hillary K. Kipruto, Martin Muhingo Githiomi, Brenda Nyambura Mungai

Vittorio Addona

" Despite high tuberculosis (TB) treatment success rate, treatment adherence is one of the major obstacles to tuberculosis control in Kenya. Our objective was to identify patient-related factors that were associated with time to TB treatment interruption and the geographic distribution of the risk of treatment interruption by county. Data of new and retreatment patients registered in TIBU, a Kenyan national case-based electronic data recording system, between 2013 and 2014 was obtained. Kaplan-Meier curves and log rank tests were used to assess the adherence patterns. Mixed-effects Cox proportional hazards modeling was used for multivariate analysis. Records from 90,170 patients were …

Methods For Diagnosing And Treating Alzheimer's Disease (Ad) Using The Molecules That Stabilize Intracellular Calcium (Ca2+) Release, Philip W. Landfield, John C. Gant, Eric M. Blalock, Kuey-Chu Chen, Olivier Thibault, Nada M. Porter

Pharmacology and Nutritional Sciences Faculty Patents

The subject technology relates, in part, to a method of treating Alzheimer's Disease (AD), early-stage AD, elevated risk of AD, mild cognitive impairment (MCI), or other forms of age-related cognitive decline in a subject in need thereof by administering to the subject a molecule that promotes calcium-release stabilization in ryanodine receptors (RyRs) and/or inosital triphosphate receptors (InsP3Rs) in brain cells. Diagnostic methods using calcium-release stabilizing immunophilins, junctophilins or calmodulin are also disclosed.

Using Survival Analysis To Identify Risk Factors For Treatment Interruption Among New And Retreatment Tuberculosis Patients In Kenya, Enos O. Masini, Omar Mansour, Clare E. Speer, Vittorio Addona, Christy L. Hanson, Joseph K. Sitienei, Hillary K. Kipruto, Martin Muhingo Githiomi, Brenda Nyambura Mungai

Faculty Publications

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Despite high tuberculosis (TB) treatment success rate, treatment adherence is one of the major obstacles to tuberculosis control in Kenya. Our objective was to identify patient-related factors that were associated with time to TB treatment interruption and the geographic distribution of the risk of treatment interruption by county. Data of new and retreatment patients registered in TIBU, a Kenyan national case-based electronic data recording system, between 2013 and 2014 was obtained. Kaplan-Meier curves and log rank tests were used to assess the adherence patterns. Mixed-effects Cox proportional hazards modeling was used for multivariate analysis. Records from 90,170 patients were …

Diagnostic And Treatment Problems Of Primary Sclerosingcholangitis, Rezky Aulia Nurleili, Intan Airlina F, Anna Mira Lubis

Jurnal Penyakit Dalam Indonesia

Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with high incidence reported in America (1/100.000 population), but there is still no data available in Indonesia. The best management of this disease is still not found. Thus, in this article author will discuss about the case of PSC in 49-years male patients hospitalized in Cipto Mangunkusumo hospital Jakarta and its treatment.

The Changing Landscape Of Biosimilars In Rheumatology, Thomas Dorner, Vibeke Strand, Paul Cornes, Joao Goncalves, Laszlo Gulacsi, Jonathan Kay, Tore K. Kvien, Josef S. Smolen, Yoshiya Tanaka, Gerd R. Burmester

Jonathan Kay

Biosimilars remain a hot topic in rheumatology, and some physicians are cautious about their application in the real world. With many products coming to market and a wealth of guidelines and recommendations concerning their use, there is a need to understand the changing landscape and the real clinical and health-economic potential offered by these agents. Notably, rheumatologists will be at the forefront of the use of biosimilar monoclonal antibodies/soluble receptors. Biosimilars offer cost savings and health gains for our patients and will play an important role in treating rheumatic diseases. We hope that these lower costs will compensate for inequities …

Putting Parity Into Practice – Integrating Opioid-Use Disorder Treatment Into The Hospital Setting, Laura Fanucchi, Michelle R. Lofwall

Center for Health Services Research Faculty Publications

No abstract provided.

Embodied Narratives: The Influence Of Dance/Movement Therapy On The Mood Of Hospitalized Children, Ashlea Palafox

Creative Arts Therapies Theses

The purpose of this qualitative collective case study was to understand how my Blanche Evan’s based dance/movement therapy treatment influenced mood for children on my case load in an inpatient general medical pediatrics unit. Patients participated in a minimum of one dance/movement therapy (DMT) session based on: availability, schedule of the subjects’ other medical treatments, and discharge date. Data collection methods included researcher journaling and audio recorded semi-structured interviews with participants and their caretakers following a one-hour dance/movement therapy session. Data was analyzed using thematic narrative analysis with a focus on the conversation between interview data and journal entries. Through …

Chronic Bronchitis, Dhwani Chotalia

Nursing Student Class Projects (Formerly MSN)

Overall incidence of chronic bronchitis is increasing in the community. Long-term side effects negatively affect quality of life of patients. This poster presentation attempts to provide more details on chronic bronchitis. Extensive details on the pathophysiology, signs & symptoms, nursing implications are provided to help the reader understand the disease process, management and prevention strategies of chronic bronchitis.

The Crisis Of Opiates In Appalachia, James B. Becker Md

James Becker

No abstract provided.

Gram-Negative Bacteria And Sepsis, Christine D. Ridge

Nursing Student Class Projects (Formerly MSN)

Today’s medical world encompasses an environment in which gram-negative bacteria that once were defeated with common antibiotics, have now become resistant. Gram-negative bacteria like Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterobacter, and Acinetobacter are pathogens that are an emerging threat causing sepsis due to multidrug-resistance (Pop-Vicas & Opal, 2014, p.189). The multidrug-resistance mechanisms of gram-negative bacteria coupled with a patient population commonly seen in hospital settings, that consist of immunocompromised adults due to advancing age, comorbidities (e.g. AIDS, history of transplants, diabetes, and chemotherapy), and immunotherapies, create an environment for advanced infection or sepsis to take place.

Complications of multidrug-resistant gram-negative bacteria …

Effects Of A Novel Right Brain Intervention On Stuttering Frequency In Unfamiliar Speech Tasks, Chelsea Beatrice Stewart

USF Tampa Graduate Theses and Dissertations

Developmental stuttering persists in approximately 1% of the United States population. Stuttering has been shown to impact overall quality of life. The present study examines the effects of a Novel Right Brain Intervention on two female participants with persistent developmental stuttering. The aim of the study was to determine whether encouraging greater activation of the right hemisphere, specifically the pre-SMA, via complex left-handed movements, prior to speech production, would lead to a reduced stuttering frequency and severity in people who stutter (PWS). It was hypothesized that each participant would reduce stuttering symptoms and behaviors following the intervention due to the …

Chlor-Amidine, A Novel Pad Inhibitor, As An Effective Drug For The Treatment Of Ulcerative Colitis And Prevention Of Colorectal Cancer, Erin Witalison

Theses and Dissertations

Ulcerative colitis (UC) is a chronic inflammatory bowel disease that affects the quality of life of millions of patients worldwide. This disease is associated with inflammation and ulceration of the colonic epithelium, leading to an increased risk for the development of UC-associated colorectal cancer (CRC). Current UC medications are designed to manage the symptoms and induce remission; however, several challenges are faced with current treatment options. 5-aminosalicyclic acid and corticosteroids have few side effects, but have limited efficacy and often the disease becomes refractory. Biologics are introduced after initial treatments fail, but serious side effects are often associated with these …

Effects Of A Novel Right Brain Intervention On Stuttering In Familiar And Structured Speech Tasks, Josalyn Elizabeth Perry

USF Tampa Graduate Theses and Dissertations

Over 3 million Americans are disfluent due to developmental stuttering. Current evidence-based treatments typically consist of a rigorous schedule of intensive therapy, followed by the need for maintenance of skills, placing high demands on self-monitoring of one’s speech at all times. Relapse after treatment is very common, at 84%. The demand for further research into treatment possibilities for stuttering is on the forefront. Previous research has connected neural activations in people who stutter (PWS) and people with chronic nonfluent aphasia. The aim of this study was to determine if a novel intervention, based on a treatment for anomia, would change …

“A Wound That Never Heals”: Health-Seeking Behaviors And Attitudes Towards Breast Cancer And Cancer In General Among Women In Nakirebe, Uganda, Ann Louise Tezak

USF Tampa Graduate Theses and Dissertations

The scale and severity of cancer, specifically breast cancer, remains significantly different across the spectrum of low-income to high-income countries. This study explores women’s beliefs about breast cancer and associated prevention and health-seeking behaviors in a rural area of Uganda. Through a critical medical anthropological perspective, the study examines the social, cultural, and economic factors that shape women’s understanding of cancer, and breast cancer specifically, and that influence their use of biomedical services. Data were collected over a three-month period through 35 in-depth interviews and two focus groups with 10 women older than 18 years in the rural setting of …

Effects Of Olanzapine And Betahistine Co-Treatment On Serotonin Transporter, 5-Ht2a And Dopamine D2 Receptor Binding Density, Jiamei Lian, Xu-Feng Huang, Nagesh Pai, Chao Deng

Xu-Feng Huang

Olanzapine is widely used in treating multiple domains of schizophrenia symptoms but induces serious metabolic side-effects. Recent evidence has showed that co-treatment of betahistine (a histaminergic H1 receptor agonist and H3 receptor antagonist) is effective for preventing olanzapine-induced weight gain/obesity, however it is not clear whether this co-treatment affects on the primary therapeutic receptor binding sites of olanzapine such as serotonergic 5-HT2A receptors (5-HT2AR) and dopaminergic D2 receptors (D2R). Therefore, this study investigated the effects of this co-treatment on 5-HT2AR, 5-HT transporter (5-HTT) and D2R bindings in various brain regions involved in antipsychotic efficacy. Female Sprague Dawley rats were administered …

How To Manage Knee Arthritis: Best Practices For Treatment Prior To Orthopaedic Referral, Ali Oliashirazi Md, Alex Caughran Md, Zain Quazi Md, Grant Buchanan Md, Akash Sharma, Franklin D. Shuler Md, Phd

Franklin D. Shuler

Osteoarthritis (OA) of the knee is a debilitating disease in which degeneration of the joint space cartilage can lead to life-altering pain and stiffness. The prevalence of OA has a strong correlation with age, with evidence of radiographic knee OA found in 37.4% of persons older than 60 years of age. According to the Agency for Healthcare Research and Quality’s (AHRQ) 2013 report, osteoarthritis was ranked the second most expensive condition for Medicare and private insurers, with over 90% of the hospitalizations for OA involving a knee or hip replacement. It is projected that by 2030 the number of primary …

How To Manage Knee Arthritis: Best Practices For Treatment Prior To Orthopaedic Referral, Ali Oliashirazi Md, Alex Caughran Md, Zain Quazi Md, Grant Buchanan Md, Akash Sharma, Franklin D. Shuler Md, Phd

Ali Oliashirazi

Osteoarthritis (OA) of the knee is a debilitating disease in which degeneration of the joint space cartilage can lead to life-altering pain and stiffness. The prevalence of OA has a strong correlation with age, with evidence of radiographic knee OA found in 37.4% of persons older than 60 years of age. According to the Agency for Healthcare Research and Quality’s (AHRQ) 2013 report, osteoarthritis was ranked the second most expensive condition for Medicare and private insurers, with over 90% of the hospitalizations for OA involving a knee or hip replacement. It is projected that by 2030 the number of primary …

Interventions For Problem Gamblers In The Correctional System, Nigel E. Turner Ph.D., Flora Matheson

International Conference on Gambling & Risk Taking

The prevalence rates of problem gambling in the adult correctional population are 5 to 10 times higher than those found in the general population. The purpose of this study is to examine the type of interventions used to deal with this population. We conducted a combination of literature review and key informant study to examine the state of programming for problem gambling for clients who experience incarceration. The published literature on this topic is remarkably sparse. In fact only two peer reviewed published studies were identified that formally evaluated a treatment program for problem gambling for clients in these settings. …

Meeting The Unique Treatment Needs Of Female Gamblers: A Workbook And Webinar Effectiveness Pilot Study, Roberta R. Boughton, Farah Jindani, Nigel Turner

International Conference on Gambling & Risk Taking

While past decades have seen a dramatic increase in the number of women who gamble and develop consequent problems, treatment services are being underutilized in Ontario, especially by women.

This pilot aimed to be responsive to this concern, circumventing barriers by inviting access to support through the use of two interventions. One was a mailed self-help workbook designed for women. The second utilized the workbook in a clinician facilitated group context using teleconferencing in conjunction with webinar technology. This small pragmatic pilot aimed to both get feedback on the helpfulness of the workbook and to explore the feasibility of using …

The Calgets Story: The Impact Of 5 Years Of State-Funded Treatment, Timothy W. Fong, Terri Sue Canale-Dalman, Michael Campos, Richard Rosenthal, Rory Reid, Brett Abarbanel

International Conference on Gambling & Risk Taking

This presentation will review the history, development and current state-funded treatment programs offered in California. Treatment outcome data from 5 years of operations will be reviewed highlighting the impact that treatment has had on gambling disorder and affected individuals. Clinical characteristics and predictors of treatment success and treatment failures from both residential treatment and outpatient treatment settings will be presented. This presentation will also describe the pitfalls, successes and lessons learned in creating a statewide treatment program that will help in inform and educate any policy maker, administrator, healthcare provider or legislator who is responsible for creating and delivering government-sponsored …

The Story Of Patrick’S: The First Center For Children With Autism In Nigeria, Dotun Akande, Alissa Briggs, Hatim A. Omar

Pediatrics Faculty Publications

Autism Spectrum Disorder (ASD) is one of the most common developmental disorders. However, there are still no epidemiological studies of ASD in African countries. In Nigeria, many children are diagnosed with ASD late or only if there are symptoms that severely inhibit their ability to function. Moreover, there are limited treatment options. This paper will describe the efforts of Patrick Speech and Languages Centre (Patrick’s), the first center in Nigeria specifically for children with ASD, which was set up to assess and treat autism.

"What's App?" Utilizing Evidence Based Medicine Apps In The Clinical Setting, Kathryn C. O'Donovan

BU Well

The medical community has utilized evidence-based medicine, or EBM, in practice for decades, and healthcare personnel are used to the idea of utilizing research and statistics to determine the treatment of patients. However, as technology advances, the use of electronics and EBM apps has increased in the clinical setting. While there are advantages to clinicians having resources at their fingertips as they talk with patients, there are also hurdles that could harm or offend patients. So as healthcare inevitably becomes more and more electronic, can providers strike the balance needed to effectively use EBM apps in practice to provide optimum …

Determining A Protocol: Rate Versus Rhythm Control In Atrial Fibrillation - A Quality Of Life Study., Samuel Dogbey, Marlea Lee

Physician Assistant Capstones, 2016 to 2019

In the United States alone, approximately 6 million people are estimated to have atrial fibrillation (AF)1. Those with AF are at a dangerously high risk for the development of stroke and/or death from emboli that form secondary to the deadly arrhythmia. Much controversy exists in the medical field surrounding the best way to treat AF to reduce both the associated morbidity and mortality. This study sought to bring clarity to the controversy by analyzing clinical trials comparing rhythm control vs. rate control of atrial fibrillation. Three studies were used to evaluate which method better increased quality of life for those …

Legal, Structural, And Ethical Barriers To Prevention And Treatment Of Hiv/Aids: A Review Of Malaysia And Kazakhstan, Amanda S. Volk

Public Health Undergraduate Program

The HIV/AIDS epidemic in nations that use Islamic scripture in law has faced several challenges. The conservative ethical and political approach to the epidemic has been ineffective in halting the spread of and treating the existence of HIV/AIDS. It is expected that there will be several structural barriers to obtaining care, treatment, and prevention services for HIV/AIDS in these nations particularly for vulnerable populations such as Men who have Sex with Men (MSM), People Who Inject Drugs (PWID), and sex workers. This research will investigate and analyze research, laws, politics, ethics, and structure in the nations of Malaysia and Kazakhstan …

Nurses' Knowledge Of Eating Disorders, Carly S. Price

Undergraduate Honors Theses

Eating Disorders are a range of disorders marked by abnormal eating habits. These habits can often have a detrimental effect on the body and have the potential to complicate acute medical problems if they are a pre-existing condition. Due to this, it is important that members of the healthcare team be aware of the nature of these disorders from both a physical and mental health perspective in order to provide the best, most holistic care. In this study, individuals with nursing experience in acute medical and acute psychiatric care were asked 11 questions concerning the assessment and knowledge of eating …