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Skeletal muscle

Health and Exercise Physiology Honors Papers

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The Comparison Of Endothelial Permeability At 48 Hours Post Skeletal Muscle Injury In Male And Female Mice At Various Ages, Sabrina Tusavitz May 2020

The Comparison Of Endothelial Permeability At 48 Hours Post Skeletal Muscle Injury In Male And Female Mice At Various Ages, Sabrina Tusavitz

Health and Exercise Physiology Honors Papers

We compared endothelial permeability at 48 hours post skeletal muscle injury in male and female mice at 1 month, 2 months, 3, 6 and 12 months of age. We hypothesized that the female mice would show more permeability at 48 hours post injury than the male mice at all ages. Our findings were more complicated as permeability following injury trends down with age in females, and up with age in males. These findings could be beneficial for medical professionals to tailor an injured athlete’s treatment to their age and sex since there are permeability and therefore possibly inflammation differences.


Examining Permeability And Contractility Of Skeletal Muscle In Castrated Male Mice, Evan Scott Apr 2020

Examining Permeability And Contractility Of Skeletal Muscle In Castrated Male Mice, Evan Scott

Health and Exercise Physiology Honors Papers

A common method of treating skeletal muscle injury is temperature therapy. Temperature affects one of the initial aspects of skeletal muscle healing, the increasing of vascular permeability. Previous data accumulated from the Ursinus College Skeletal Muscle Lab suggests that vascular permeability following temperature therapy is different between the anatomically intact male and female mice. However, there have not been any studies to date that are able determine the cause of these permeability differences following temperature treatment. In addition, it is currently unclear how increased vascular permeability affects skeletal muscle healing. A possible cause for these differences is the increased presence …